Clinical trials: Lasers
Prostate Cancer
Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal)
This is a multicenter observational study of patients undergoing focal therapy for prostate cancer in Asia
- Trial name
- ProAMFocal (NCT06491056)
- Testing
- Focal Therapy for Prostate Cancer
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore General Hospital
Diabetic Retinopathy
Pilot Study of Laser Photocoagulation Therapy for Diabetic Macular Edema
This study will compare the side effects of two laser treatments for diabetic macular edema, a common condition in patients with diabetes.
- Trial name
- NCT00069056
- Testing
- Laser Treatment
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- National Eye Institute (NEI)
Prostate Cancer, Prostatic Neoplasms
MR Image Guided Therapy in Prostate Cancer
Background: One way to treat prostate cancer is to use a laser to direct extreme heat to a small area of the prostate. The heat destroys tumor cells but does not affect healthy tissue.
- Trial name
- NCT01377753
- Testing
- Visualase Thermal Therapy System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Cancer Institute (NCI)
Open-angle Glaucoma (OAG), Ocular Hypertension (OHT)
Direct vs Standard SLT for Glaucoma: A Noninferiority Trial
This study compares two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower eye pressure and prevent vision loss.
- Trial name
- NCT07408154
- Testing
- Direct Selective laser Trabeculoplasty
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Medical University of South Carolina
Irritable Bowel Syndrome
ConfocAl endomicroSCopy bAsed Diet Trial in IBS
After a thorough baseline evaluation, IBS patients will be exposed to nutrients while undergoing confocal laser endomicroscopy (CLE).
- Trial name
- CASCADE (NCT05097872)
- Testing
- Diet
- Where
- Belgium
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Wounds and Injuries
Laser Speckle Imaging for Wound Perfusion Monitoring (WoundImager)
The purpose of this study is to investigate the efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- NCT01675583
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CW Optics, Inc.
Plantar Fasciitis
High Intensity Laser VS High Power Pain Threshold Ultrasound in Treatment of Plantar Fasciitis
The purpose of the study is to 1. Investigate the Effect of High-intensity laser therapy versus High power pain threshold ultrasound on pain level in patients with plantar fasciitis. 2.
- Trial name
- HILT - HPPTUS (NCT07462169)
- Testing
- High intensity laser therapy, High power pain threshold ultrasound, Conventional treatment
- Where
- 2 sites in Egypt
- Volunteers
- 51 people
- Sponsor
- Cairo University
Diabetic Nephropathies
Effect of High-intensity Laser Exercise Versus Moderate-intensity Aerobic Exercise on Diabetic Polyneuropathy Patients
Diabetic poly neuropathy (DPN) is a length-dependent, symmetrical sensorimotor poly neuropathy and is among the most prevalent and challenging consequences of diabetes4.
- Trial name
- NCT06884462
- Testing
- High-intensity laser (HIL), moderate-intensity aerobic exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Deraya University
Striae; Albicantes
Stretch Marks on Abdomen
The primary objective of this study is to determine the effect of Stratacel® wound dressing on cosmetic outcomes following 1064/532nm picosecond laser (Picoway®, Syneron Candela Corp, Wayland, MA, USA) treatment of abdominal…
- Trial name
- NCT03750422
- Testing
- Picoway, Stratacel, Aquasonic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Weiss Ring
Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters
The goal of this clinical trial is to compare in the efficacy and safety of Nd:YAG laser vitreolysis for symptomatic vitreous floaters.
- Trial name
- VVF (NCT05800353)
- Testing
- YAG vitreolysis
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Dongyang People's Hospital
Chronic Shoulder Pain
The Effect of High-intensity Laser Therapy in Patients With Chronic Shoulder Pain
The aim of this study was to investigate the effects of biostimulating, analgesic and noninvasive high intensity laser therapy on pain, functionality and quality of life in patients with chronic shoulder pain.
- Trial name
- NCT05062941
- Testing
- Conventional physiotherapy, High-intensity laser therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Marmara University
Malocclusion, Angle Class II
Efficacy of Minimally Invasive Surgical Technique in Accelerating Orthodontic Treatment
Thirty six patients needs therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines will be divided randomly into two groups : piezocision group and the ER:yttrium aluminum garnet…
- Trial name
- NCT02606331
- Testing
- Piezosurgery, ER:YAG laser
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Chronic Heart Failure, Coronary Disease
Role of Endothelial Function, Muscular Fitness and Metabolism in Functional Activity in Patients With Chronic Heart Failure (CHF)
Shortness of breath, fatigue, and exercise intolerance are clinical symptoms of chronic heart failure (CHF). Recent studies suggested that peripheral impairment was the major cause of clinical symptoms, and mechanism may be…
- Conditions
- Chronic Heart Failure, Coronary Disease, Dilated Cardiomyopathy
- Trial name
- NCT01139086
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Burn Scar Patients
Fractional Nonablative 1540 nm Laser Resurfacing for Burn Scars- A Randomised Controlled Trial
The objective was to evaluate the efficacy of 1540 nm fractional laser treatment of mature burn scars.
- Trial name
- NCT00689650
- Testing
- 1540 nm fractional laser
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Epiretinal Membrane
Topical Use of Corticosteroid to Prevent Epiretinal Membrane Following Retinal Tear
In this prospective randomized controlled double blind pilot clinical study, we aim to assess whether administration of a topical corticosteroid would attenuate epiretinal membrane formation following development of retinal tears…
- Trial name
- NCT02412059
- Testing
- Prednisolone acetate
- Volunteers
- 200 people
- Sponsor
- Unity Health Toronto
Orthodontic Tooth Movement, Low Level Laser Therapy
Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined
Orthodontic treatment is often prolonged, requiring years to achieve desirable outcomes. The prolonged duration of treatment increases the risk of complications such as root resorption, periodontal damage, and patient…
- Conditions
- Orthodontic Tooth Movement, Low Level Laser Therapy, Canine Retraction
- Trial name
- NCT07626580
- Testing
- Micro-osteoperforation, Low Level Laser Therapy and Micro-osteoperforations Combined
- Where
- Pakistan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Acne, Scar
Comparison of Treatments for Atrophic Acne Scars
Acne scars have high prevalence, significant impact on quality of life and are a therapeutic challenge for dermatologists. Previous studies have shown promising results for the treatment of acne scars with non-ablative fractional…
- Trial name
- NCT02025088
- Testing
- Laser, Microneedling
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- Thaís Hofmann Cachafeiro
Cataracts
Laser Cataract Surgery With the Femtosecond Laser Technology
The purpose of this study is to prove the efficacy and safety of the Femtosecond laser to create a clear corneal incision during cataract surgery.
- Trial name
- NCT01382823
- Testing
- Femtosecond Laser
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Innovative Medical
Astigmatism, Cataract
Astigmatism Management With Iris-registration Guided Corneal Relaxing Incisions or Toric IOLs During Cataract Surgery
Most of the patients presenting for cataract surgery also have pre-existing corneal astigmatism which if left uncorrected can adversely affect visual and refractive outcomes after cataract surgery.
- Trial name
- NCT05561296
- Testing
- Femtosecond laser assisted cataract surgery with astigmatism management
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kenneth J Rosenthal
Central Serous Chorioretinopathy
Navigated Microsecond Laser for Chronic Central Serous Chorioretinopathy: MICROPULSE
MICROPULSE study aims to evaluate the efficacy of navigated microsecond laser (nMSL) for chronic central serous chorioretinopathy (CSCR).
- Trial name
- MICROPULSE (NCT05679180)
- Testing
- micropulse laser
- Sponsor
- University Hospital, Bordeaux
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