Clinical trials: Lasers
Photodamage
Laser 360iQ: Optimal Light-laser Combination Therapy
To assess the safety and efficacy of light-laser combination therapy for the improvement of skin color, tone, texture and laxity
- Trial name
- NCT04519723
- Testing
- Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Achilles Tendinopathy
Comparative Effects of Laser and Extracorpeal Shock Wave in Patients With Achilles Tendinopathy.
Achilles tendinopathy is a prevalent condition characterized by pain, swelling, and impaired function of the Achilles tendon, commonly affecting athletes and active individuals.
- Trial name
- NCT06986759
- Testing
- Laser, Extracorporeal shock wave therapy protocol
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Myopic Astigmatism
A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm study evaluating the safety and effectiveness of the Technolas® TENEO 317 Model 2 (version 1.28 US software) Excimer Laser when used in LASIK surgery…
- Trial name
- NCT07377474
- Testing
- TENEO 317 Model 2 (1.28 US) Excimer Laser
- Volunteers
- 32 people
- Sponsor
- Bausch & Lomb Incorporated
Central Retinal Vein Occlusion With Macular Edema
Evaluation of the "Treat-and-extend" Scheme in Patients With Retinal Vein Occlusion (RVO) With and Without LASER Treatment of Ischaemic Retinal Areas
The purpose of this study is to determine if additional panretinal photocoagulation of ischemic areas following retinal vein occlusion (RVO) may reduce the rate of recurrence and allow longer treatment intervals in anti-Vascular…
- Trial name
- PEARL (NCT02522897)
- Testing
- Ranibizumab, Laser
- Volunteers
- 60 people
- Sponsor
- PD. Dr. med. Armin Wolf
Proiriftrative Diabetic Retinopathy
Comparison of Two Laser Therapy Methods for PDR
Proliferative diabetic retinopathy (PDR) is treated with conventional pan retinal photocoagulation (PRP) which can improve the visual prognosis in this complication significantly.
- Trial name
- PDR (NCT01232179)
- Testing
- conventional prp, targeted prp
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Gastric Subepithelial Tumors
Endoscopic Ultrasound-guided Needle-based Confocal Laser Endomicroscopy for Diagnosis of Gastric Subepithelial Tumors
The differential diagnosis of gastric subepithelial tumors by endoscopic ultrasound is currently suboptimal. Needle-based confocal laser endomicroscopy (nCLE) is a novel endoscopic technique, which is compatible with the 19-gauge…
- Trial name
- NCT02936986
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Shandong University
Laser, Muscle; Fatigue, Heart
Photobiomodulation, Cryotherapy Combined With Compression, and Massage for Recovery
Skeletal muscle fatigue is an inevitable phenomenon in the training and competition routine for many crossfit athletes, which can impair their physical performance and predispose them to musculoskeletal injuries.
- Conditions
- Laser, Muscle; Fatigue, Heart, Muscle Damage
- Trial name
- NCT05627141
- Testing
- Photobiomodulation; Cryotherapy, Massage
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Anhanguera
Lateral Epicondylitis (Tennis Elbow)
Comparison of Extracorporeal Shock Wave Therapy and Low-Level Laser Therapy in Patients With Lateral Epicondylitis
Background: Lateral epicondylitis is a common musculoskeletal condition characterized by pain and functional impairment of the elbow, often associated with degenerative changes in the common extensor tendon.
- Trial name
- NCT07564713
- Testing
- ESWT Group, LLLT Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hitit University
Temporomandibular Joint Disorders
Low Level Laser Therapy in the Treatment of Temporomandibular Joint Disorders (TMJDs) Related Pain
The Low Level Laser Therapy (LLLT) has been recently introduced with success in the management of the pain associated to this condition.
- Trial name
- NCT03119324
- Testing
- B-Cure® diode laser, Nimesulide Ratiopharm® and Flexiban®
- Volunteers
- 90 people
- Sponsor
- University of Roma La Sapienza
Peri-implantitis
Evaluation of Fractalkine and Its Receptor in Peri-implantitis
In this study, mechanical debridement group, Er:YAG laser group and diode laser group will be compared in terms of reducing peri-implant sulcus depth in the treatment of peri-implantitis.
- Trial name
- NCT06685523
- Testing
- Subgingival debridement, Er:YAG laser decontamination, Diyot laser decontamination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kubilay BARIŞ
Peri-Implantitis
Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study
The American Association of Oral and Maxillofacial Surgeons estimated that 69% of adults ages 35 to 44 have lost at least one permanent tooth.
- Trial name
- NCT03100435
- Testing
- Er:YAG Laser, Carbon Fiber Curette
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Tufts University
Kidney Stones, Nephrolithiasis
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney stones are a common health problem and may recur frequently, which can affect quality of life and kidney function. Retrograde intrarenal surgery (RIRS) is a minimally invasive treatment used for renal stones, but treatment…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07516535
- Testing
- Direct In-Scope Suction, Flexible and Navigable Suction Ureteric Access Sheath
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Diabetic Retinopathy
HORNBILL: A Study to Test Different Doses of BI 764524 in Patients Who Have Had Laser Treatment for a Type of Diabetic Eye Disease Called Diabetic Retinopathy With Diabetic Macular Ischemia
This is a study in people with a type of diabetic eye disease called diabetic retinopathy with diabetic macular ischemia. People who have had laser treatment for their diabetic retinopathy can participate in the study.
- Trial name
- HORNBILL (NCT04424290)
- Testing
- BI 764524
- Where
- 19 sites in United States, United Kingdom
- Volunteers
- 45 people
- Sponsor
- Boehringer Ingelheim
Arterial Disease of Legs, Atherosclerosis of Artery
Safety and Efficacy of Cold Laser Plaque Ablation for Lower Limb Arterial Stenosis and Occlusive Lesions
This study is a prospective, multi-center, randomized controlled study, which evaluates the effectiveness and safety of cold laser plaque ablation for lower limb arterial stenosis and occlusive lesions from intermittent…
- Trial name
- NCT06211127
- Testing
- Cold laser plaque ablation, The excimer laser
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xuanwu Hospital, Beijing
Spinal Fusion, Chronic Lower Back Pain
Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery
After spinal fusion and decompression surgery there is a possible risk of developing chronic back pain. After surgery there is typically inflammation around the operation site and this inflammation can be painful and debilitating…
- Trial name
- NCT06282770
- Testing
- Laser Diode Brace
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Fibrous Hyperplasia on Oral Mucosa
Comparison of ER:YAG Laser, CO2 Laser and Scalpel Excision of Fibrous Hyperplasia on the Buccal Mucosa
The aim of the RCT is to analyse clinical and histopathological particularities for excisional biopsies of fibrous hyperplasia in the buccal mucosa performed with Er:YAG laser, CO2 laser and scalpel.
- Trial name
- NCT03001791
- Testing
- Excisional biopsy with Er:YAG laser, Excisional biopsy with CO2 laser, Excisional biopsy with scalpel
- Where
- Switzerland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Bern
Presbyopia
Safety & Efficacy of the Laser Scleral Microporation Procedure (Taiwan)
A new minimally invasive procedure for treating presbyopia is being evaluated to determine if there is improvement in near and intermediate vision after treatment.
- Trial name
- NCT04151446
- Testing
- Laser Scleral Microporation
- Where
- 2 sites in Taiwan
- Volunteers
- 11 people
- Sponsor
- ACE Vision Group, Inc.
Chronic Apical Periodontitis
Effects of Irrigation Activation Methods on Periapical Healing in Chronic Apical Periodontitis
This study aims to evaluate the effects of different irrigation activation methods on periapical healing in teeth with chronic apical periodontitis.
- Trial name
- NCT07850895
- Testing
- Sonic Irrigation Activation, Passive Ultrasonic Irrigation, Laser-Activated Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Recep Tayyip Erdogan University
Nipple Lesions
Low-Level Laser Therapy (LLLT) Treatment for Breast-Feeding Women With Painful Nipple Lesions
Around 30 to 90 percent of all breastfeeding women suffer from painful and sore nipple lesions. Reasons for these lesions are still not completely clarified.
- Trial name
- NCT04259619
- Testing
- Low-Level Laser Therapy
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- University of Zurich
IBS, Food Intolerance
Confocal Laser Endomicroscopy in IBS Patients
This study will assess dynamic effects of two major antigens on the duodenal mucosa by confocal laser endomicroscopy (CLE). Patients will be blinded to the antigens used (wheat, yeast).
- Trial name
- NCT02313207
- Testing
- FODMAP
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
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