Clinical trials: Lasers
Hypertrichosis
Comparison of Efficacy, Safety and Tolerability of Two Different 810 nm Diode Lasers for Hair Reduction
The purpose of this research study is to compare two different 810 diode laser systems (Soprano XL (SHR Mode)and Light Sheer Duet) for laser hair removal.
- Trial name
- NCT01212172
- Testing
- Soprano/SHR, LightSheer
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Facial Dermatoses, Seborrheic Keratoses
Dermatosis Papulosa Nigra
DPN is a disorder among darkly pigmented patients, manifested by small, benign, variants of seborrheic keratoses, predominantly on the face.
- Trial name
- DPN (NCT00710203)
- Testing
- Pulsed dye laser, Curettage, Electrodesiccation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Davis
Dental Caries
Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
The objective of this clinical study is to evaluate whether the use of the new CO2 - 9.3μm short-pulsed laser increases the caries resistance of occlusal pit and fissure surfaces in patients in addition to fluoride therapy.
- Trial name
- LaserFissure (NCT02357979)
- Testing
- Laser, Fluoride
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Precancerous/Nonmalignant Condition
Photodynamic Therapy Using Topical Aminolevulinic Acid in Treating Patients With Actinic Keratosis
RATIONALE: Photodynamic therapy uses a drug that becomes active when it is exposed to a certain kind of light. When the drug is active, abnormal cells are killed.
- Trial name
- NCT00524485
- Testing
- aminolevulinic acid, laser therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Roswell Park Cancer Institute
Glaucoma
Steroids After Laser Trabeculoplasty for Glaucoma
The purpose of this study is to determine whether the choice of post-operative eye drop administered after selective laser trabeculoplasty (SLT) for glaucoma affects the efficacy in lowering intraocular pressure (IOP).
- Trial name
- SALT (NCT00981435)
- Testing
- Prednisolone 1%, Ketorolac, Artificial Tears
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Stanford University
Lung Carcinoma
Needle-Based Confocal Laser Endomicroscopy for Diagnosis of Lung Cancer in Patients With Peripheral Pulmonary Nodules
This clinical trial compares the addition of needle-based confocal laser endomicroscopy (nCLE) and fluorescein to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS TBNA) with EBUS TBNA alone for the diagnosis…
- Trial name
- NCT05556525
- Testing
- Fluorescein, Image-Guided Needle Confocal Laser Endomicroscopy, Ultrasound-Guided Transbronchial Needle Aspiration
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Localized Lipodystrophy
Evaluation of the Candela 1064nm:Nd:YAG Laser for Skin Tightening
The purpose of this research study is to evaluate effectiveness of a non-ablative (does not remove skin) treatment for cellulite (dimpled fat) in conjunction with skin tightening using the Candela GentleYAG laser.
- Trial name
- IH062905 (NCT00585715)
- Testing
- 1064 nm Nd:YAG laser
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of California, Irvine
Tattoo Removal
Pilot Study of Multi-wavelength Laser for Tattoo Removal
To evaluate the safety and efficacy of an investigational version of the Cutera enLighten laser that offers muliple wavelengths for tattoo removal.
- Trial name
- NCT03290547
- Testing
- Cutera enLighten laser
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Ureteral Stone
Temperature Profiles During Laser Activation in Ureteroscopic Lithotripsy
The primary aim of this study is to investigate the temperature profiles in the renal pelvis during ureteroscopic Thulium Fiber Laser activation using different settings.
- Trial name
- NCT05677425
- Testing
- Temperature measurement
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Haukeland University Hospital
Barrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia
Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)
This is a prospective randomized clinical trial examining how IRIS (Intelligent Real-time Image Segmentation) affects biopsy patterns in VLE (Volumetric laser endomicroscopy).
- Conditions
- Barrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia, Barrett's Esophagus With Low Grade Dysplasia, Barrett's Esophagus With High Grade Dysplasia
- Trial name
- NCT03814824
- Testing
- IRIS (Intelligent real-time image segmentation), VLE (Volumetric laser endomicroscopy)
- Where
- 3 sites in United States
- Volunteers
- 148 people
- Sponsor
- Northwell Health
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Vulvar Intraepithelial Neoplasia (VIN)
Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia
The primary objective of this study is to evaluate the incidence of vulva dysplasia recurrence within 12 months of treatment with Carbon Dioxide (CO2) laser ablation or ultrasonic aspiration.
- Trial name
- NCT02875561
- Testing
- Sonopet Ultrasonic Aspirator, CO2 Laser Ablation
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Colorado, Denver
Overweight and Obesity, Weight Loss
Low-level Laser and Lifestyle Modifications
The purpose of this research study is to evaluate the effectiveness of Low Level Laser Therapy in combination with Lifestyle Modifications in helping people reduce the extra weight and size in the central body region
- Trial name
- LLLT (NCT05083442)
- Testing
- Low Level Laser Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prostate Cancer, Prostatic Neoplasms
MR Image Guided Therapy in Prostate Cancer
Background: One way to treat prostate cancer is to use a laser to direct extreme heat to a small area of the prostate. The heat destroys tumor cells but does not affect healthy tissue.
- Trial name
- NCT01377753
- Testing
- Visualase Thermal Therapy System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Cancer Institute (NCI)
Cataract
Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes
This study is designed to compare the effectiveness of LenSx laser arcuate relaxing incisions vs. manual (blade) arcuate relaxing incisions in patients with low, but significant, levels of astigmatism.
- Trial name
- NCT04126174
- Testing
- femtosecond laser system arcuate corneal incision, Manual LRI
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Gainesville Eye Associates
Scarring, Acne
Evaluation of the Cutera Enlighten™ Laser With Micro-Lens Array (MLA) Handpiece Attachment
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm picosecond pulse duration laser and an investigational micro-lens array (MLA) handpiece…
- Trial name
- NCT03430921
- Testing
- Enlighten™ Laser and a MLA Attachment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Musculoskeletal Pain
The Effect of the Erchonia GVL Low Level Laser Therapy on Neck and Shoulder Pain
This study is to see if applying green and violet low level laser light to the neck and shoulders can help to reduce pain in the neck and shoulders.
- Trial name
- NCT04895618
- Testing
- Erchonia GVL
- Where
- 3 sites in United States
- Volunteers
- 43 people
- Sponsor
- Erchonia Corporation
Plantar Fascitis
Low-Level Laser Therapy for Plantar Fasciitis
Plantar fasciitis (PF), a degenerative injury of the connective tissue in the foot, results in pain-related disability in Service Members and contributes to decreased physical activity and excessive healthcare costs.
- Trial name
- NCT05763381
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- The Geneva Foundation
Oral Squamous Cell Carcinoma, Squamous Cell Carcinoma of Oropharynx
Laser Mucite ORL : Effectiveness of Laser Therapy for Mucositis Induced by a Radio-chemotherapy in Head and Neck Cancer
The purpose of the study is to assess in a randomized, double blind, controlled, multi-center, phase III study, the efficacy of low level diode laser (100 MW, 658 Nm), in the prevention and treatment of radiochemotherapy-induced…
- Conditions
- Oral Squamous Cell Carcinoma, Squamous Cell Carcinoma of Oropharynx, Squamous Cell Carcinoma of Hypopharynx, Oral Mucositis
- Trial name
- LaserMucite (NCT01772706)
- Testing
- low level laser therapy
- Where
- 6 sites in France
- Volunteers
- 97 people
- Sponsor
- Institut Cancerologie de l'Ouest