Clinical trials: Lasers
Periodontal Disease
Efficacy of Laser Therapy for Periodontitis
The aim of this study is to evaluate the efficacy of diode laser in addition to periodontal treatment in periodontitis patients and to investigate their effects on gingival crevicular fluid (GCF) cytokine levels before and after…
- Trial name
- NCT07013162
- Testing
- High power diode laser + SRT, Low diode diode laser + SRT, Curettage (SRT) only
- Where
- 2 sites in Yemen
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Primary Open Angle Glaucoma, Glaucoma
A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients
Background Glaucoma is a progressive optic neuropathy characterized by elevated intraocular pressure (IOP), leading to irreversible vision loss.
- Conditions
- Primary Open Angle Glaucoma, Glaucoma, Primary Open Angle Glaucoma or Ocular Hypertension
- Trial name
- NCT07076303
- Testing
- Direct Selective Laser Trabuloplasty
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brian Shafer
Newborn Distress
A Pilot Study Using Laser Speckle Imaging of Neonate Cerebral Vasculature
The researcher want to know whether reflections of light can be used to provide real-time pictures of blood vessel formation around infants' heads. This approach is called laser speckle imaging
- Trial name
- NCT01166880
- Testing
- Laser Speckle Imaging
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Temporomandibular Disorders (TMD), TMJ Disorder
Machine Learning for Evaluating and Diagnosing Temporomandibular Disorders
This study aims to improve clinical efficiency and effectiveness in treating Temporomandibular Disorders (TMD). The researchers will integrate machine learning technology with clinical examination data, CBCT, and MRI to identify…
- Conditions
- Temporomandibular Disorders (TMD), TMJ Disorder, TMJ Pain
- Trial name
- NCT07771296
- Testing
- Low-Level Laser Acupuncture, Proprioceptive Training, Stabilization Splint Treatment
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- En Chu Kong Hospital
Cataract
Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes
This study is designed to compare the effectiveness of LenSx laser arcuate relaxing incisions vs. manual (blade) arcuate relaxing incisions in patients with low, but significant, levels of astigmatism.
- Trial name
- NCT04126174
- Testing
- femtosecond laser system arcuate corneal incision, Manual LRI
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Gainesville Eye Associates
Port Wine Stains
Port Wine Stains Treatment Matrix RF Study
The purpose of this study is to evaluate the efficacy and safety of the Matrix RF for Port Wine Stains based on clinical and histological analyses.
- Trial name
- NCT01101360
- Testing
- Matrix RF, Matrix RF followed by Pulse Dye Laser, Pulse Dye Laser followed by Matrix RF
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Syneron Medical
Wound Heal, Vestibular Abnormality
Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty
Randomized controlled parallel designed clinical study aimed to compare vestibule depth gain and dimensional changes of wound area in individuals who underwent vestibule deepening surgery using diode laser and conventional…
- Conditions
- Wound Heal, Vestibular Abnormality, Low-level Light Therapy, Surgical Wound
- Trial name
- NCT05252260
- Testing
- Diode Laser, Conventional Surgery, Low level laser therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Vitiligo, Depigmented Scars
Comparative Study Using Dermabrasion vs CO2 Laser & Collagen Dressing vs Vaseline Gauze in MKTP
The purpose of this study is to: 1. Compare two different techniques in the melanocyte keratinocyte transplant procedure: Use of carbon dioxide laser versus use of dermabrasion 2.
- Conditions
- Vitiligo, Depigmented Scars, Depigmentation
- Trial name
- MKTP (NCT02038257)
- Testing
- MKTP (melanocyte keratinocyte transplant procedure), Collagen Dressing, Vaseline Impregnated Gauze
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Dry Eye Disease
Femtosecond Small Incision Lenticular Extraction in Comparison to Femtosecond Laser Insitu Keratomileusis Regarding Dry Eye Disease
Comparison of femtosecond small incision lenticule extraction (FS-SMILE) versus Femtosecond laser Insitu Keratomileusis (FS-LASIK) regarding dry eye disease (DED) and corneal sensitivity (CS) after those refractive surgeries.
- Trial name
- NCT04477421
- Testing
- FS-SMILE, S-LASIK
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Al-Rasheed University College
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Retrospective Review a Comprehensive Case Database of HoLEP Procedure Performed by a Single Surgeon
Persistent detrusor overactivity (DO) after transurethral prostatectomy results in symptomatic failure in more than one third of the patients.
- Trial name
- NCT01604148
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Lax Vaginal Introitus
The Effect of Additional Laser Treatments.
Women previously treated with vaginal CO2 laser will receive an additional treatment 6 months after cessation of previous laser treatment or a sham laser treatment.
- Trial name
- NCT04111952
- Testing
- CO2 laser
- Where
- Israel
- Volunteers
- 253 people
- Sponsor
- Rambam Health Care Campus
Intracorneal Ring, Keratoconus
Long-term Result of Placing Intracorneal Rings in Keratoconus Using Laser
Intracorneal rings are indicated in patients whose central cornea does not present opacity and whose visual acuity is not satisfied despite correction with lenses or linked to an intolerance to lenses.
- Conditions
- Intracorneal Ring, Keratoconus, Laser
- Trial name
- STAK (NCT05596838)
- Testing
- Intracorneal rings placement
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Elsan
Pelvic Girdle Pain
Low Level Laser Therapy in Persistent Pelvic Girdle Pain
Persistent pregnancy-related pelvic girdle pain is common, 2-5% av all women given birth is suffering from disabling daily pain with high impact on quality of life.
- Trial name
- NCT02789735
- Testing
- Active laser therapy
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
Burning Mouth Syndrome
Effects of Photobiomodulation in Burning Mouth Syndrome
The main objective of this study is to assess the effects of Photobiomodulation with Low-level Laser Therapy to the pain management in Burning Mouth Syndrome patients, besides assessing their impact on the different aspects of…
- Trial name
- NCT04034849
- Testing
- Photobiomodulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Rosa María López-Pintor Muñoz
Rosacea
Potassium-titanyl Phosphate (KTP) Laser vs KTP Laser and Ivermectin Cream for Facial Rosacea
Rosacea is a frequent chronic inflammatory disease affecting mainly the face but also eyes and scalp. Rosacea is classified into 3 types: erythemato-teleangiectatica, papulopustulosa and phymatosa.
- Trial name
- KIR (NCT06033352)
- Testing
- KTP laser, Ivermectin 1% cream
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta
MoDi Twin Placental Imaging
Twin-twin transfusion syndrome (TTTS) can arise in monochorionic, diamniotic (MoDi), those identical twins arising from division of a single fertilized ovum at 4-8 days gestational age (GA) or monochorionic, monoamniotic (MoMo or…
- Conditions
- Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta, Monochorionic Twins, Ultrasound Doppler
- Trial name
- NCT07667647
- Testing
- Verasonics Vantage 256 Ultrasound
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Carilion Clinic
Dermatologic Disease, Vitiligo
Comparison of Cyclic On-off and Continuous Excimer Laser Treatment for Vitiligo
OBJECTIVE: To investigate the efficacy of the cyclic on-off treatment compared to the conventional continuous excimer laser treatment. DESIGN: A randomized, controlled, split-body, non-inferiority study.
- Trial name
- NCT03047733
- Testing
- The XTRAC Excimer Laser System, Topical tacrolimus 0.1% ointment
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Ajou University School of Medicine
Circumferential Reduction, Waist Circumferential Reduction
BTL-9000 Low Level Laser Therapy for the Waist Circumferential Reduction
Prospective, two-arm, randomized study of the effectiveness of the BTL-9000 LLLT in achieving 3 cm or greater average waist circumferential reduction in LLLT group of subjects relative to the base line and 1 cm or greater…
- Trial name
- NCT02023385
- Testing
- BTL-9000 LLLT
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Scarring, Acne
Evaluation of the Cutera Enlighten™ Laser With Micro-Lens Array (MLA) Handpiece Attachment
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm picosecond pulse duration laser and an investigational micro-lens array (MLA) handpiece…
- Trial name
- NCT03430921
- Testing
- Enlighten™ Laser and a MLA Attachment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Cataract
Topical Bromfenac for Intraoperative Miosis and Pain Reduction
To evaluate the effect of bromfenac ophthalmic solution 0.09% for reduction of intraoperative miosis and pain in patient who have undergone femtosecond laser-assisted cataract surgery.
- Trial name
- NCT03831984
- Testing
- 0,09% Bromfenac, 0,1% sodium hyaluronate
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de La Luz
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