Clinical trials: Lasers
Acne Scars
Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars
Acne scarring is an unfortunate consequence of inflammatory acne vulgaris that often leads to significant cosmetic and psychosocial impacts.
- Trial name
- NCT03901417
- Testing
- Fraxel Restore (Non-ablative Fractional Laser), Fraxel Restore (Non-ablative fractional laser) and SkinPen (Microneedling Device)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Coronary Artery Disease, Coronary Artery Calcification
Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
The FRACTURE Trial is a prospective, non-randomized, single-arm, multicenter, interventional study in US and international centers.
- Trial name
- FRACTURE (NCT06181240)
- Testing
- Intravascular lithotripsy
- Where
- 46 sites in United States, Belgium and 5 more
- Volunteers
- 426 people
- Sponsor
- Bolt Medical
Diabetic Macular Oedema
Intravitreal Triamcinolone for Clinically Significant Diabetic Macular Oedema That Persists After Laser Treatment (TDMO)
The trial will test the hypothesis that an intravitreal injection of triamcinolone is safe and efficacious for patients with clinically significant diabetic macular oedema that is recalcitrant to conventional laser therapy
- Trial name
- NCT00167518
- Testing
- Triamcinolone acetate
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- University of Sydney
Scar
Efficacy of Different Densities of Fractional Carbon Dioxide in Treatment of Post Burn Scars
This study aims to compare effectiveness of different densities of carbon dioxide fractional laser in the treatment of postburn scar.
- Trial name
- NCT03416660
- Testing
- Fractional Carbon Dioxide laser
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Cairo University
Peri-Implantitis
Non-Surgical Laser Treatment for Peri-Implantitis: Er:YAG & Diode Laser
A prospective, randomized clinical trial with a 3-month duration was designed to evaluate the efficacy of non-surgical treatment for peri-implantitis.
- Trial name
- NCT06890117
- Testing
- Ultrasonic Scalers with EMS PI tip and Saline Irrigation, Er:YAG (2940nm) and Diode (808nm) Laser
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Musculoskeletal Pain
The Effect of the Erchonia GVL Low Level Laser Therapy on Neck and Shoulder Pain
This study is to see if applying green and violet low level laser light to the neck and shoulders can help to reduce pain in the neck and shoulders.
- Trial name
- NCT04895618
- Testing
- Erchonia GVL
- Where
- 3 sites in United States
- Volunteers
- 43 people
- Sponsor
- Erchonia Corporation
Chronic Lateral Epicondylitis
ESWT vs HILT in Chronic Lateral Epicondylitis
This randomized controlled trial aims to compare the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) and High-Intensity Laser Therapy (HILT) in patients with chronic lateral epicondylitis.
- Trial name
- ESWT vs HILT (NCT07654790)
- Testing
- Extracorporeal shock wave therapy, Conventional Physical Therapy, High-power intinsty laser
- Volunteers
- 72 people
- Sponsor
- Kafrelsheikh University
Rheumatoid Arthritis
Laser Acupuncture in Rheumatoid Arthritis Geriatric Patients
Studying the effect of laser acupuncture on geriatric patients with rheumatoid arthritis
- Trial name
- NCT04758689
- Testing
- Laser, exercise, and methotrexate, Exercise, and methotrexate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Local Anesthesia of the Skin.
Fractional Laser Assisted Delivery of Anesthetics
The purpose of this study is to assess the efficacy of fractional CO2 laser assisted delivery of topically applied anesthetics (articaine hydrochloride 40 mg/ml and epinephrine 10 μg/ml solution and EMLA cream) regarding to…
- Trial name
- NCT02246179
- Testing
- AFXL, AHES, EMLA cream
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Netherlands Institute for Pigment Disorders
COVID-19
Probe-based Confocal Laser Endomicroscopy in Critically Ill COVID-19 Patients
The study is devoted to the comparative analysis of the data received in patients with COVID-19 lung pathology using the method of probe-based confocal laser endomicroscopy of distal airways and two reference methods: high…
- Trial name
- NCT04451889
- Testing
- miniprobe Alveoflex
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- Federal Research Clinical Center of Federal Medical & Biological Agency, Russia
Open Angle Glaucoma, Ocular Hypertension
Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy
The aim of this study is to evaluate the efficacy of selective laser trabeculoplasty after a prior failed phacoemulsification and Eximer Laser Trabeculectomy.
- Conditions
- Open Angle Glaucoma, Ocular Hypertension, Cataract
- Trial name
- SLT (NCT02434250)
- Testing
- Selective Laser Trabeculoplasty
- Where
- Switzerland
- Volunteers
- 203 people
- Sponsor
- University of Zurich
Wound - in Medical Care
Evaluation of Skin Stiffness Changes in Wounds Before and After Low-Level Laser Therapy
Chronic wounds and impaired healing remain a major clinical challenge, particularly in patients with diabetes, vascular disease, or age-related skin fragility.
- Trial name
- NCT07177274
- Testing
- Low Level Laser Therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Asia University
Port-Wine Stain
Effect of Pulsed Dye Laser on Photodynamic Therapy of Port-Wine Stains
Port-wine stain (PWS) is a congenital capillary malformation with an incidence of 3-5/1000 newborns and grows commensurately with the affected individual.
- Trial name
- NCT04536740
- Testing
- PDT treatment device
- Volunteers
- 68 people
- Sponsor
- Gang Ma
Presbyopia
Intrastromal Presbyopia Correction by Means of a Femtosecond Laser
This clinical study is an open, prospective, multi-centre eye study consisting of three study arms to determine the safety and efficacy of intrastromal incisions for the correction of visual acuity on presbyopic eyes.
- Trial name
- NCT01025050
- Testing
- Intrastromal Correction of Presbyopia
- Where
- 4 sites in Germany
- Volunteers
- 58 people
- Sponsor
- Technolas Perfect Vision GmbH
Healthy
Role of the Laser Pointer in Budgeting Fluoroscopy Time and Radiation Exposure
Thirty (30) orthopaedic surgeons from the University of Florida Department of Orthopaedics and Rehabilitation will be recruited and enrolled in the study to determine whether having a laser pointed on a fluoroscopy machine can…
- Trial name
- NCT02051582
- Testing
- Surgeons using fluoroscopy with laser pointer, Surgeons using fluoroscopy without laser pointer
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Florida
Laser Thermotherapy, Stress Urinary Incontinence
Factors Affecting Therapeutic Efficacy of Vaginal Laser Therapy for Female Stress Urinary Incontinence, and the Effect of Vaginal Laser Therapy on Overactive Bladder Syndrome and Sexual Function
The main aim of this study is to elucidate factors affecting treatment efficacy of vaginal laser therapy.
- Trial name
- NCT03693690
- Testing
- Vaginal laser thermotherapy
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Far Eastern Memorial Hospital
Fordyce Spots
1726-nm Diode Laser for Lip Fordyce Spots
Fordyce spots are benign ectopic sebaceous glands commonly affecting the lips and vermilion border, often causing cosmetic concern.
- Trial name
- NCT07300917
- Testing
- Accure 1726-nm Diode Laser
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Venus Research Center
Varicose Veins
Endovenous Radiofrequency Versus Laser Ablation for the Treatment of Great Saphenous Vein Reflux
our aim is to compare early outcomes following EVL 1320 nm and segmental RF in a randomized study.
- Trial name
- NCT02080013
- Testing
- radiofrequency
- Volunteers
- 5 people
- Sponsor
- Ain Shams University
Venous Thromboembolism
Filter Initial & Long Term Evaluation After Placement and Retrieval Registry
A prospective data registry for all patients who undergo IVC (Inferior Vena Cava) filter placement or retrieval at Stanford. Potential enrollees will already be undergoing the procedure.
- Trial name
- FILTER (NCT01158482)
- Testing
- IVC Filter Placement or Retrieval
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Stanford University
High Intensity Laser Therapy, Psoriasis
Efficacy of Pulsed High Intensity Laser Therapy in Psoriatic Hand Arthritis
The purpose of the study was to evaluate the therapeutic efficacy of pulsed high intensity level laser therapy in improving symptoms of psoriatic hand arthritis.
- Conditions
- High Intensity Laser Therapy, Psoriasis, Hand
- Trial name
- NCT06665282
- Testing
- Pulsed high intensity laser therapy, Routine physical therapy program
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
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