Clinical trials: Lasers
Drusen
Sub-threshold Micro-Pulse Laser Therapy for Drusen of Dry AMD
To investigate the efficacy and safety of sub-threshold micro-pulse laser therapy for drusen of dry age-related macular degeneration (AMD) .
- Trial name
- NCT03968575
- Testing
- laser treatment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Eye Hospital of Wenzhou Medical University
White Spot Lesion
Effect of CO2 Laser on Enamel White Spot Lesion Formation Around Orthodontic Brackets
This study aims to evaluate the clinical effect of CO2 laser on enamel resistance to white spot lesions formation around orthodontic brackets.
- Trial name
- NCT03114475
- Testing
- CO2 laser irradiation
- Where
- 2 sites in Syria
- Volunteers
- 25 people
- Sponsor
- Damascus University
Varicose Veins, Varicose Veins of Leg With Long Saphenous Vein Distribution
Steam Ablation Versus Endovenous Laser Ablation for the Treatment of Great Saphenous Veins
Endovenous laser ablation is a common therapy of great saphenous vein insufficiency with a very high success rate. It works by heating and thereby obliterating the vein.
- Trial name
- LAST (NCT02046967)
- Testing
- Endovenous laser ablation with 940 nm bare fiber, Endovenous steam ablation with steam vein sclerosis system.
- Where
- Netherlands
- Volunteers
- 237 people
- Sponsor
- Erasmus Medical Center
Acute Cholecystitis, Colorectal Cancer
Safety and Feasibility of ActivSightTM in Human
ActivSightTM combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Acute Cholecystitis, Colorectal Cancer, Diverticulitis, Colonic, Obesity, Morbid
- Trial name
- NCT04633512
- Testing
- ActivSight
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Obesity, Dyslipidemias
Evaluation of Systemic Microvascular Endothelial Function in Metabolically Healthy Obesity
Obesity is known to be a risk factor for cardiovascular disease (CVD), type 2 diabetes mellitus, gastrointestinal tract disease, respiratory problems (such as obstructive sleep apnea), joint and muscle problems, reproductive…
- Trial name
- NCT04233528
- Testing
- Evaluation of systemic skin microvascular endothelial function
- Where
- Brazil
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Tooth Impaction | {Tooth} | Dental, Corticosteroid
Comparison of the Effects of Protocols Applied After Surgical Extraction of Impacted Mandibular Third Molars
Following the surgical extraction of the most commonly impacted mandibular third molars, the first group was planned to receive methylprednisolone, the second group hyaluronic acid, the third group ozone therapy, the fourth group…
- Conditions
- Tooth Impaction | {Tooth} | Dental, Corticosteroid, Hyaluronic Acid, Ozone
- Trial name
- NCT06900907
- Testing
- Diode laser, Hyaluronic acid, Ozone
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Batman University
Myofascial Pain Syndrome
Efficacy of Photobiomodulation Therapy Using 980nm Versus 635nm Diode Lasers for Treatment of Myofascial Pain
This randomized controlled clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) using two different diode laser wavelengths (980 nm and 635 nm) in the treatment of myofascial pain associated with…
- Trial name
- LLLTsEMG (NCT07069764)
- Testing
- Doctor smile 635nm For Arm 1, Doctor smile 980 nm For Arm2
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Institute of Laser Enhanced Sciences
Benign Prostatic Hyperplasia
Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP)
Benign prostatic hyperplasia (BPH) refers to the proliferation of smooth muscle and epithelial cells of the prostate gland. The enlarged gland has the potential to result in lower urinary tract symptoms (LUTS) secondary to either…
- Trial name
- NCT03062111
- Testing
- ProTouch Laser Enucleation of Prostate (LEP), Transurethral Resection of Prostate (TURP)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Boston University
Photorefractive Keratectomy
A Comparative Study Between Laser and Manual Removal of Corneal Epithelium for Photorefractive Keratectomy
Photorefractive keratectomy (PRK) is a laser eye surgery used to ablate the corneal stroma to correct visual refractive errors . PRK was developed in 1983 by Dr. Steven Trokel and colleagues and first performed in 1987 by Dr.
- Trial name
- NCT06748599
- Volunteers
- 64 people
- Sponsor
- Assiut University
Amyloid, Fractional
Fractional CO₂ Laser for Primary Cutaneous Amyloidosis
This randomized, controlled clinical study will evaluate the clinical and ultrastructural effects, efficacy, and safety of fractional CO₂ laser in patients with primary cutaneous amyloidosis.
- Conditions
- Amyloid, Fractional, Laser
- Trial name
- FCO2-PCA (NCT07815132)
- Testing
- Fractional CO₂ Laser
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Tanta University
Glaucoma
Clinical Evaluation of Efficacy of SLT to Topical Medication in Lowering IOP
The purpose of this study is to compare Selective laser trabeculoplasty (SLT) and topical medications for initial treatment of open-angle glaucoma /Ocular Hypertension based on intraocular pressure reduction, treatment side…
- Trial name
- NCT01639807
- Testing
- Latanoprost, SLT
- Where
- India
- Volunteers
- 600 people
- Sponsor
- Aurolab
CO2 Laser in Scars
Comparison of Co2 Laser Versus Co2 Laser With PRP in Scars
Objective: To compare the effect of Fractional Carbon dioxide Laser (FCL) Vs Fractional Carbon dioxide Laser with platelet rich plasma (PRP) in management of Scars. Study design: Randomized-controlled trial (RCT).
- Trial name
- NCT05887232
- Testing
- Fractional CO2 laser, Fractional CO2 with Platelet Rich Plasma
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital Abbottabad
Deep Overbite
Evaluation of Root Resorption During the Correction of Deep Bite With the Help of Laser Irradiation
This study aims to investigate the effectiveness of low-level laser in reducing the resorption of the roots of the upper incisors.
- Trial name
- NCT05734092
- Testing
- Traditional orthodontic treatment, Low-Level Laser
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Laser-Induced Scar, Breast Cancer
Laser Treatment of Genito-urinary Syndrome in Women
Women with genitourinary syndrome of menopause, overactive bladder, with breast or endometrial cancer are randomized to either laser treatment og sham treatment for 3 months.
- Conditions
- Laser-Induced Scar, Breast Cancer, Endometrial Cancer, Menopause
- Trial name
- NCT03238053
- Testing
- Vaginal laser treatment, laser system
- Where
- Denmark
- Sponsor
- Herning Hospital
Neck Pain, Chronic Neck Pain
Effect of Added Load on Map-Based Proprioceptive Training in Chronic Neck Pain
The purpose of this study is to find out whether adding an external load to a map-based cervical proprioceptive training program provides additional benefit for people with chronic neck pain.
- Trial name
- NCT07900295
- Testing
- Weightless map-based proprioceptive training, Weighted map-based proprioceptive training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Cataract
Femtosecond Laser for Cataract Surgery
The objective of this study is to evaluate the safety and efficacy the OptiMedica Femtosecond Laser System, also known as the Catalys™ Precision Laser System, to perform two surgical maneuvers used in the treatment of subjects…
- Trial name
- NCT02110212
- Testing
- U/S Surgery and CCC, FS Laser Surgery
- Volunteers
- 17 people
- Sponsor
- Abbott Medical Optics
Atrophic Acne Scars
Comparison of Efficacy of Carbon Dioxide Laser With Subcision Versus Platelet-Rich Plasma Bio-Fillers With Subcision for the Treatment of Atrophic Acne
This randomized controlled trial compared two combined treatment approaches for atrophic acne scars. A total of 100 patients aged 15-45 years were enrolled from the Department of Dermatology, Lahore General Hospital, Lahore, and…
- Trial name
- NCT07752186
- Testing
- Platelet-Rich Plasma Bio-Filler With Subcision, Fractional Carbon Dioxide Laser With Subcision
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Lahore General Hospital
Benign Prostatic Hypertrophy
Wolf 24 F vs. Storz 28 F Laser Sheath Size for HoLEP
The purpose of this study is to compare two different types of scopes that can be used for HoLEP. HoLEP is performed through the urethra using a Laser scope to remove obstructing prostate tissue.
- Trial name
- NCT05308017
- Testing
- Richard Wolf 24F Laser scope, Karl Storz 28F Laser Scope
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Northwestern University
Hyperhidrosis Primary Focal Axilla
Treatment of Axillary Hyperhidrosis With Long-pulsed Nd:YAG Laser or IPL
SUMMARY Objective To assess the efficacy of Nd:YAG laser treatment on eccrine sweat production in the axillae of persons experiencing excessive axillary hyperhidrosis. Design Randomised, within-person controlled clinical trial.
- Trial name
- NCT04227691
- Testing
- Long-pulsed Nd Yag laser treatment, IPL treatment
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Zealand University Hospital
Obesity
Laser Acupuncture Versus High Protein/Low Carbohydrate Diet on Endothelial Markers in Obese Females
The purpose of this study is to compare the effects of laser acupuncture and high protein low carbohydrate diet on the treatment of obesity and lowering of endothelial markers.
- Trial name
- NCT02573961
- Testing
- Laser acupuncture, high protein low carbohydrate diet, low caloric diet
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
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