Clinical trials: Lasers
Teeth, Endodontically-Treated
Application of Photodynamic Therapy and Diode Laser for Endodontic Therapy of Young Permanent Teeth
The pulp necrosis of permanent immature teeth implies the interruption of the root formation and apical closure. Diode lasers have been used in many areas of dentistry, with tendency of good results in canal and dentine…
- Trial name
- NCT03074136
- Testing
- Photodinamic therapy, Diode laser, 0.5% Sodium hypochlorite
- Where
- Serbia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Association of Paediatric and Preventive Dentists of Serbia
Corneal Biomechanics
Evaluation of the Change in the DA Ratio, IR and SSI as Parameters of Corneal Biomechanics Post Different LVC Procedures
In the study, The Investigators will compare the participates' corneal biomechanical properties including: Deformation Amplitude ratio (Da Ratio) Integrated Radius (IR) Stress strain index (SSI) All measurements will be taken…
- Trial name
- NCT05377099
- Testing
- CORVIS
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ultrasonography, Interventional
Laser-assisted Ultrasound-guided Peripheral Vein Cannulation in Cardiac Surgery
The aim of this clinical trial is to investigate the advantages of single-operator laser-assisted ultrasound-guidance comparing with traditional ultrasound guidance in peripheral venous catheterization.The primary question…
- Trial name
- NCT07079904
- Testing
- Ultrasound Guided Peripheral Vein Catheterization With or Without Laser-Assisted.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Periodontitis (Stage 3)
Er,Cr:YSGG Laser in Smokers With Stage III Periodontitis
Periodontitis is an inflammatory disease that affects the tissues supporting the teeth. If the disease progresses, it can cause loss of the tissues and bone around the teeth and lead to the formation of deep spaces, called…
- Trial name
- NCT07851584
- Testing
- Nonsurgical Periodontal Therapy, Nonsurgical Periodontal Therapy + Er,Cr:YSGG Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Okan University
Anesthesia
Assessment of Airways Mechanical Properties by FOT and LIR During Anesthesia
The aims of the present study are: 1. To evaluate the effect of the induction of anaesthesia and paralysis in terms of changes in oscillatory mechanics parameters 2.
- Trial name
- NCT01506284
- Testing
- Forced oscillatory technique (FOT) and laser interferometry (LIR).
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Uppsala University Hospital
Keratoconus
Astigmatic Vector Analysis of Posterior Cornea - a Comparison Among Healthy, Forme Fruste and Overt Keratoconus Corneas
The main purpose of this study is to determine new diagnostic criteria for an eye disease called keratoconus.
- Trial name
- NCT02698709
- Testing
- Analysis of anterior and posterior corneal surfaces
- Where
- Brazil
- Volunteers
- 698 people
- Sponsor
- University of Sao Paulo
Brain Metastases, Cancer
Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR
The purpose of this study is to assess the relationship between brain malignancy volume as defined by post-contrast T1 weighted and F18 Fluciclovine before and following LITT.
- Conditions
- Brain Metastases, Cancer, Gliomas, Glioblastoma
- Trial name
- NCT05054400
- Testing
- F18 Fluciclovine, Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Diabetes Mellitus, Macular Edema
Laser and Medical Treatment of Diabetic Macular Edema
This study will compare the side effects of two laser treatments for diabetic macular edema, a common condition in patients with diabetes.
- Trial name
- NCT00027287
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Eye Institute (NEI)
Severe Non-proliferative Diabetic Retinopathy
Safety and Effectiveness Study of 532nm Laser Subthreshold Panretinal Photocoagulation for Severe NPDR
This randomized, parallel controlled, clinical-trial aims to evaluate the therapeutic efficacy of 532nm laser partially subthreshold panretinal photocoagulation with PASCAL endpoint management function for severe…
- Trial name
- S-PRP (NCT01759121)
- Testing
- T-PRP, S-PRP
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Sun Yat-sen University
Prostatic Hyperplasia
HoLEP vs mTURP in Management of Benign Prostatic Hyperplasia
To compare the clinical outcome regarding safety and efficacy between Holmium laser enucleation of the prostate and transurethral resection of the prostate in management of benign prostatic hyperplasia.
- Trial name
- NCT04561505
- Testing
- Holmium laser enucleation of prostate, monopolar transurethral resection of prostate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Gingival Pigmentation
Vitamin C Mesotherapy Versus Diode Laser for the Management of Physiologic Gingival Pigmentation
Physiologic pigmentation affects the gingival esthetics. Laser ablation has been recently used as the most effective and reliable technique for gingival depigmentation.
- Trial name
- NCT05608057
- Testing
- Vitamin C mesotherapy, Diode laser
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Hams Hamed Abdelrahman
Irreversible Acute Pulpitis, Root Canal Treatment
Evaluation of the Effects of Different Irrigation Solutions and Activation Methods on Postoperative Pain and Quality of Life in Root Canal Treatment
Brief Summary: This prospective randomized controlled clinical trial aims to evaluate the effects of different irrigation solutions (NaOCl, HEDP) and activation methods (conventional syringe irrigation, EDDY, diode laser) on…
- Trial name
- NCT07241650
- Testing
- Irrigation with Sodium Hypochlorite and Conventional Syringe, Irrigation with Sodium Hypochlorite and EDDY, Procedure: Irrigation with Sodium Hypochlorite and Diode Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Yildirim Beyazıt University
Onychomycosis
Diode Laser Treatment of Onychomycosis
The purpose of this study is to evaluate the V-Raser diode laser system with investigational Nail Fungus Handpiece in the treatment of onychomycosis.
- Trial name
- NCT01452490
- Testing
- Diode Laser Treatment
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- ConBio, a Cynosure Company
Ulnar Nerve Entrapment at Elbow
Evaluation of the Efficacy of Low Level Laser Therapy in Ulnar Neuropathy at the Elbow
The purpose of this study is, to demonstrate the effectiveness of low-level laser therapy on symptoms, clinical and electrophysiological parameters in elbow ulnar neuropathy.
- Trial name
- NCT06086210
- Testing
- Low-level laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Gulsah Celik
Metastatic Brain Tumors, Progression
Laser Ablation After Stereotactic Radiosurgery
The need for new technologies and devices in the field of neurosurgery is well established. In April 2013, FDA cleared NeuroBlate™ System, minimally invasive robotic laser thermotherapy tool.
- Conditions
- Metastatic Brain Tumors, Progression, Radiation Necrosis, Quality of Life
- Trial name
- LAASR (NCT01651078)
- Where
- 7 sites in United States
- Volunteers
- 44 people
- Sponsor
- Monteris Medical
Wound Edges
Intraoperative CO₂ (Carbon Dioxide)
To evaluate whether intraoperative fractionated CO₂ laser treatment of surgical wound edges improves postoperative scar appearance compared with untreated wound edges following Mohs micrographic surgery (MMS).
- Trial name
- NCT07592468
- Testing
- CO2 Fractionated Laser, Non CO2 Laser Treatment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor Research Institute
Prostate Cancer
Focal Laser Ablation of Prostate Cancer
The primary objective of this study is to evaluate the safety and feasibility of Magnetic-Resonance(MR)-ultrasound image fusion-guided transrectal-based focal laser ablation (FLA) of prostate cancer using the Orion System, an…
- Trial name
- NCT04305925
- Testing
- Focal Laser Ablation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Body Contouring
Study of Low Level Laser Therapy for Body Contouring
The purpose of this study is to determine whether green diode low level laser therapy is effective for body contouring of the waist, hips and thighs.
- Trial name
- NCT00738426
- Testing
- Erchonia ML Scanner (MLS)
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
White Spot Lesion of Tooth
Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth
This study is a randomized controlled trial involving 118 children ages between 4 and 5 years to assess the remineralization effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions in primary…
- Trial name
- NCT03526276
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Experimental Pain in Healthy Human Subjects
Intra- and Inter-individual Differences of Pain
Pain is a highly subjective and variable phenomenon. Different persons perceive objectively identical nociceptive stimuli differently.
- Trial name
- NCT05616091
- Testing
- painful stimulation by using a laser device (DEKA Stimul 1340, Calenzano, Italy)
- Where
- Germany
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
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