Clinical trials: Lasers
Orthodontic Retainers, Laser Therapy
Effect of Low-Level Laser Therapy on Stability During Retention Phase.
The biggest problem in the orthodontic process is the pain and the long duration of treatment, which is also generally divided into 2 phases, namely the orthodontic tooth movement (OTM) and the retention phase.
- Trial name
- NCT05723094
- Testing
- Ga-Al-As diode laser (Ilase, USA)
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- Universiti Sains Malaysia
Laser Tattoo Removal
Clinical Evaluation of Tattoo Removal Using a Novel Dual-Wavelength, Dual-Pulse Duration Laser
A single-center prospective, open-label, uncontrolled study in 10 male or female subjects, age 18 to 65 years, who desire laser removal of a tattoo which contains all black ink.
- Trial name
- NCT02431104
- Testing
- 532-nm KTP/1064-nm Nd:YAG Dual-Pulse Duration Laser
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cutera Inc.
Exposure Laser
Evaluation of the Safety and Efficacy of Carbon Dioxide (CO2) Acupulse Laser Treatment on Urinary Stress Incontinence.
The study is intended to assess the safety and efficacy of CO2 AcuPulse laser treatment in patients with stress urinary incontinence (SUI).
- Trial name
- NCT02861391
- Testing
- CO2 AcuPulse Laser
- Where
- Israel
- Volunteers
- 125 people
- Sponsor
- Rambam Health Care Campus
Branch Retinal Vein Occlusion, Ranibizumab
Combination of Intravitreal Ranibizumab With or Without Macular Laser Photocoagulation for ME Secondary to BRVO
To investigate the efficacy of laser photocoagulation combined with ranibizumab intravitreal injection in macular edema (ME) secondary to branch retinal vein occlusion (BRVO) in long term.
- Conditions
- Branch Retinal Vein Occlusion, Ranibizumab, Laser Photocoagulation
- Trial name
- NCT03054766
- Testing
- Ranibizumab combined macular laser, Ranibizumab
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Hospital
Awake Laser, Microlaryngeal Surgery
Awake Transnasal Laser-assisted Surgery (TNLS) and Microlaryngeal Surgery for Benign Laryngeal Lesions
This is a prospective, single-cluster randomised controlled trial conducted at two tertiary referral hospitals in Hong Kong to compare the clinical and functional outcomes of office-based transnasal laser-assisted surgery (TNLS)…
- Conditions
- Awake Laser, Microlaryngeal Surgery, Benign Laryngeal Lesion, Transnasal Laser Surgery
- Trial name
- NCT05665829
- Testing
- Awake transnasal laser-assisted surgery (TNLS), Microlaryngeal surgery (MLS)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Low Level Laser Therapy, Photobiomodulation
Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia
The photobiomodulation (PBM) shows positive results in muscle performance, fatigue reduction, management of blood lactate production, analgesia and in the increase of VO2 maximal, favoring the increase of ATP production and thus…
- Conditions
- Low Level Laser Therapy, Photobiomodulation, Performance, Sport
- Trial name
- NCT05595564
- Testing
- Photobiomodulation therapy
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Prostate Neoplams, Magnetic Resonance Imaging, Laser Ablation
MRI-guided Focal Laser Ablation Prostate Cancer
Prostate cancer is the most frequent malignancy in the male population of developed countries and has a substantial socio-economic impact.
- Trial name
- NCT05370482
- Testing
- Focal laser ablation
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Radboud University Medical Center
Laser Assisted Liposuction
Laser Assisted Liposuction and Facial Autologous Fat Grafting With the LipoLife System
Multi-center, prospective, open-label, single arm study. The study aims to evaluate the safety and efficacy of Laser Assisted Liposuction procedure performed with the LipoLife system.
- Trial name
- NCT03800563
- Testing
- LipoLife system
- Where
- 2 sites in United States, Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Low Level Laser Therapy, Photobiomodulation
Influence of Power and Wavelength on Photobiomodulation Therapy for Muscle Performance in Healthy Subjects
In recent years, photobiomodulation has been studied as a means of increasing muscle performance in athletes and healthy individuals. This is possible due to the physiological changes that photobiomodulation therapy can promote.
- Conditions
- Low Level Laser Therapy, Photobiomodulation, Performance, Sport
- Trial name
- NCT04809415
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Knee Osteoarthritis, Laser Therapy
Evaluation of the Effect of High-intensity Laser Therapy in Knee Osteoarthritis
The aim of this study is to evaluate the effects of high intensity laser therapy (HILT) on range of motion, pain, quality of life, muscle strength and femoral cartilage thickness in patients with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Laser Therapy, Muscle Strength
- Trial name
- NCT05510648
- Testing
- high-intensity laser therapy
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Periodontitis, Laser
BMP-2 and ALP Levels Following Laser Therapy With Scaling and Root Planing in Periodontitis- RCT.
Patients with periodontitis will be treated by either SRP only or SRP in combination with laser. Samples from GCF will be collected immediately after treatment and at 3 months follow-up time.
- Trial name
- NCT05555420
- Testing
- SRP+Laser
- Volunteers
- 20 people
- Sponsor
- Cairo University
Low Level Laser Therapy
Effect of Low-level Laser Therapy on Orthodontic Tooth Movement
The objective of this trial is to investigate the effect of low-level laser therapy (LLLT) on orthodontic tooth movement during maxillary molar distalization over 12-week observation period.
- Trial name
- NCT05550168
- Testing
- Low Level Laser therapy
- Where
- Cyprus
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Laser Assistance to Improve ICSI Outcome
Laser Assisted ICSI; Has it Role Whatsoever?
laser-assisted ICSI (LA-ICSI) was described to be a new method combining a less invasive ICSI technique with assisted hatching.This procedure is usually used for MII oocytes possessing oolemma breakage difficulties, but why not…
- Trial name
- NCT04455412
- Testing
- Laser Assisted ICSI
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Royal Fertility Center, Egypt
Lasers, Atrophy of Vagina
The Use of Laser in the Treatment of Atrophic Vulvovaginitis
This study evaluates the efficacy and security of laser for atrophy treatment. Half of participants will receive the laser treatment and the other half placebo.
- Conditions
- Lasers, Atrophy of Vagina, Atrophy Vulva
- Trial name
- NCT04297319
- Testing
- Laser diiodo
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- Hospital Italiano de Buenos Aires
Low Level Laser Therapy, Pain
Effect of the Diode Laser (940nm) on Orthodontics
To evaluate the effect of the low power density 940nm diode laser in the total relief of dental crowding during the alignment phase and the perception of pain in patients who initiate orthodontic treatment.
- Conditions
- Low Level Laser Therapy, Pain, Crowding, Tooth
- Trial name
- NCT05469451
- Testing
- Low level laser therapy
- Where
- Colombia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Intestinal Metaplasia, Artificial Intelligence
Artificial Intelligence-assisted Confocal Laser Endomicroscopy Identification of Intestinal Metaplasia Severity
Currently, the Correa cascade is a widely accepted model of gastric carcinogenesis. Intestinal metaplasia is a high risk factor for gastric cancer.
- Conditions
- Intestinal Metaplasia, Artificial Intelligence, Confocal Laser Endomicroscopy
- Trial name
- NCT05462743
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shandong University
Intestinal Metaplasia of Gastric Mucosa, Confocal Laser Endomicroscopy
Artificial Intelligence Confocal Laser Endomicroscopy for Real-time Assessment of Gastric Cancer Risk.
Current national guidelines recommend the use of OLGIM score to evaluate the risk of gastric cancer in patients, and close gastroscopic monitoring should be performed after OLGIM grade III/IV.
- Trial name
- NCT05459428
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shandong University
the Efficacy of Fractional Co2 Laser in Nail Psoriais
Fractional CO2 Laser Versus Pulsed Dye Laser in Nail Psoriasis
The aim of this work is to assess the efficacy and safety of fractional CO2 laser therapy in comparison to pulsed dye laser (PDL) in the treatment of nail psoriasis.
- Trial name
- NCT05415839
- Testing
- Laser
- Volunteers
- 30 people
- Sponsor
- Cairo University
Low-level-laser Theraphy, Anesthesia, Local
Anethesia Efficacy on Teeth With MIH (Molar Incisor Hypomineralisation)
Difficulty in achieving anesthesia in teeth with molar incisor hypomineralisation (MIH) is a frequently reported clinical problem.
- Conditions
- Low-level-laser Theraphy, Anesthesia, Local, Molar Incisor Hypomineralization
- Trial name
- MIH (NCT05344014)
- Testing
- Photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kocaeli University