Clinical trials: Late Effect
Dysarthria As Late Effect of Stroke
The Effectiveness of Smartphone-Based Speech Therapy for People with Post-Stroke Dysarthria
This clinical trial aims to determine if a new smartphone-based speech therapy is effective self-treatment method for patients with post-stroke dysarthria.
- Trial name
- NCT05877950
- Testing
- Smartphone-based speech therapy, Home-based speech therapy
- Volunteers
- 100 people
- Sponsor
- Ewha Womans University Seoul Hospital
Quality of Life, Adverse Effects
International Validation of the QLQ-OH17 for Oral Health
Assessment of oral and dental problems is seldom routine in clinical oncology, despite the potential negative impact of these problems on nutritional status, social function and quality of life (QoL).
- Conditions
- Quality of Life, Adverse Effects, Late Effects, Cancer
- Trial name
- QLQ-OH17 (NCT01724333)
- Where
- 14 sites in France, Germany and 8 more
- Volunteers
- 585 people
- Sponsor
- Oslo University Hospital
Cognitive Impairment, Cognitive Decline
Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy
Randomized, placebo-controlled, double-blinded, parallel group clinical trial to investigate if 6 months of oral lithium tablets (S-lithium 0,5-1,0 mmol/l) will prevent cognitive decline after brain radiotherapy in pediatric…
- Conditions
- Cognitive Impairment, Cognitive Decline, Radiotherapy Side Effect, Radiotherapy; Complications
- Trial name
- LiBRA (NCT06051240)
- Testing
- Lithium
- Where
- 2 sites in Sweden
- Volunteers
- 84 people
- Sponsor
- Region Stockholm
Dysarthria as Late Effect of Stroke
Efficacy of a Digital Therapeutic for People With Dysarthria After Stroke
This pilot trial will establish the feasibility of a new digitized speech rehabilitation developed for patients with post-stroke dysarthria.
- Trial name
- NCT05146765
- Testing
- Mobile application, Treatment as usual
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ewha Womans University Seoul Hospital
Survivorship, Late Effect
PCSP Implementation Study
This study protocol describes the design and methods of the PanCareSurPass (PCSP) multi-country implementation study of the Survivorship Passport v2.0 (short: PCSP implementation study), which is part of the PCSP project that has…
- Trial name
- NCT05982587
- Testing
- Survivorship passport (SurPass) delivery
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- Istituto Giannina Gaslini
Dysphagia, Late Effect of Stroke
Capsaicin for Post-stroke Dysphagia
Randomised, double blind, Phase 2 Trial to evaluate the efficacy of oral Capsaicin in patients with post-stroke dysphagia in the (sub-)acute setting.
- Trial name
- CADYS (NCT04470752)
- Testing
- Capsaicin 1% oral solution, InOrpha Solution
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- Georg Kägi, MD
Left-sided Hemiplegia Affecting Dominant Side as Late Effect of Cerebrovascular Accident
Balance Rehabilitation With Sensory Recalibration After Stroke
The main objective of this study is to test the effectiveness of a rehabilitation program with cervical vibration and/or prism adaptation in patients with left hemiplegia on balance.
- Trial name
- AVCPOSTIM (NCT01677091)
- Testing
- Cervical vibration, Prism adaptation, Conventional rehabilitation
- Where
- 8 sites in France
- Volunteers
- 114 people
- Sponsor
- Rennes University Hospital
Hemiparesis as Late Effect of Cerebrovascular Disease
Role of Functional Translation After Immersive Virtual Reality Exposure in Persons With Stroke
This is a single-blinded randomized control trial aiming to explore the use of immersive virtual reality (VR) training in conjunction with real-life tasks therapy in 75 first time stroke patients with upper limb weakness.
- Trial name
- NCT04360460
- Testing
- Immersive virtual reality + related functional translation into real-life, Immersive virtual reality + non-related translation into real-life
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Loma Linda University
Shoulder Pain, Late Effect
An Individualised Treatment vs. a Minimal Program in Women With Late-term Shoulder Impairments After Breast Cancer.
In breast cancer patients late-term upper limb sequelae, such as shoulder pain and impaired shoulder function remain common after primary breast cancer surgery.
- Conditions
- Shoulder Pain, Late Effect, Breast Cancer, Rehabilitation
- Trial name
- NCT05277909
- Testing
- The expert assessment of shoulder impairments and individualised treatment plan, A minimal physiotherapeutic rehabilitation program delivered in a pamphlet
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Vejle Hospital
Dysphagia, Late Effect of Stroke, Deglutition Disorders
Bio-feedback Treatment for Dysphagic Post-stroke Patients
The primary purpose of the study is to evaluate whether the effect of bio-feedback dysphagia treatment is more effective than a control treatment in post-stroke patients.
- Trial name
- BIO_DYS (NCT03247374)
- Testing
- "ProComp5 Infiniti" Biofeedback, Standard Speech and Language Therapy
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Childhood Cancer, Late Effects
Young Survivors at Kantonsspital Aarau, Switzerland
The Young Survivors at Kantonsspital Aarau project assesses the prevalence and severity of late effects in survivors of childhood and adolescent cancer according to the modified CTCAE criteria prospectively.
- Trial name
- NCT04811794
- Testing
- Physical examination, diagnostic tests, laboratory tests, Personal history
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Kantonsspital Aarau
Covid-19, SARS-CoV2
SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)
Overall mortality of COVID-19 is variable and has been reported to be between less than 1% and 7%. Many authors around the world also reported data on hospitalization rate, need for intensive care unit (ICU) care and need for…
- Conditions
- Covid-19, SARS-CoV2, Surgery, Surgical Procedure; Complications, Late Effect of Complications
- Trial name
- SUROCO (NCT04458337)
- Where
- Canada
- Volunteers
- 318 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Quality of Life, Late Effect
Health-related Quality of Life and Late Effects Among SURVivors of Cancer in Adolescence and Young Adulthood: The SURVAYA Study
Rationale: Adolescent and young adult (AYA) cancer survivors, diagnosed between 18-39 years, much more than children, suffer from delay in diagnosis, lack of centralization of care, age-adjusted expertise and follow-up care.
- Conditions
- Quality of Life, Late Effect, Survivorship, Lifestyle
- Trial name
- NCT05379387
- Where
- Netherlands
- Volunteers
- 4,000 people
- Sponsor
- The Netherlands Cancer Institute
Cancer, Cognitive Late Effects
Efficacy of Atomoxetine Therapy Versus Placebo for Cognitive Late Effects
The purpose of the study is to evaluate the effectiveness and safety of atomoxetine in enhancing attention and concentration among childhood survivors of cancer.
- Trial name
- NCT00255138
- Testing
- Atomoxetine
- Where
- United States
- Sponsor
- Temple University
Childhood Cancer, Genetic Predisposition
Genetic Risks for Childhood Cancer Complications in Switzerland
The objectives of the GECCOS project are to identify genetic variants associated with complications of childhood cancer using genotype-phenotype association studies.
- Conditions
- Childhood Cancer, Genetic Predisposition, Late Effect
- Trial name
- GECCOS (NCT04702321)
- Testing
- Procedure: Biospecimen Collection, Procedure: Medical Chart Review
- Where
- Switzerland
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Geneva
Muscle Weakness, Late Effect of Burn
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
This study will measure efficacy of early in-patient exercise as an adjunct to current Standard of Care (SOC) for 96 patients in a multi-centre trial.
- Conditions
- Muscle Weakness, Late Effect of Burn, Muscle; Fatigue, Heart, Burn Rehabilitation
- Trial name
- MP-10 (NCT02739464)
- Testing
- Exercise + SOC PT/OT, SOC PT/OT
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke, Dysphagia, Late Effect of Stroke
Investigating Program of Food Preparation on Diet Improvement for Patients With Stroke
This is a randomized controlled behavioral intervention trial to assess the efficacy of investigating program of food preparation on diet improve patients with stroke.
- Trial name
- NCT04347863
- Testing
- Group swallowing disorder diet preparation program
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Taiwan Adventist Hospital
Quality of Life, Cancer
Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
This project aims to explore, in depth, the burden of hearing loss and tinnitus on cancer survivors. Using semi-structured interviews, audiograms and a variety of validated questionnaires, the specific impact ototoxicity has on…
- Conditions
- Quality of Life, Cancer, Hearing Loss, Sensorineural, Tinnitus, Subjective
- Trial name
- NCT04281953
- Testing
- High frequency audiometry, Short-Form 36-Item Questionnaire (SF-36), Hearing handicap inventory for adults/elderly (HHIA/HHIE)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Late Effects of Hypofractionated Radiotherapy in Breast Cancer
Late-term Effects of Hypofractionated Chest Wall and Regional Nodal Irradiation in Patients With Breast Cancer
Survival of breast cancer patients has improved with multimodality treatment. Hypofractionated radiotherapy (RT) is rapidly emerging as one of the options for breast cancer patients after breast conservation surgery (BCS) but…
- Trial name
- LEHR (NCT04175821)
- Testing
- Hypofractionated radiotherapy
- Volunteers
- 1,770 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Late Effects of Cerebrovascular Accident
Main Idea Perception of Written Stories and in Pictures Among Impaired Right Hemisphere Patients
Main idea perception of written stories and in pictures among impaired right hemisphere patients Abstract The right hemisphere is considered to complement the language processing abilities of the opposite hemisphere; it is…
- Trial name
- stroke (NCT02897791)
- Testing
- written evaluations
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center