Clinical trials: Leakage, Anastomotic
Anastomotic Leak, Gastric Cancer
Anastomotic Leak Testing in Gastrectomy
Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis.
- Conditions
- Anastomotic Leak, Gastric Cancer, Surgery, Testing, Reality
- Trial name
- NCT04292496
- Testing
- Introperative leak testing
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Nanchong Central Hospital
Anastomotic Leak, Surgical Site Infection
Bowel Prep vs Non-Bowel Prep for Laparoscopic Colorectal Surgery
Research Question: Are anastomotic leak and surgical site infection rates equivalent in patients having laparoscopic bowel resections without bowel preparation vs those having bowel preparation? Bowel preparation is a distressing…
- Trial name
- NCT00643084
- Testing
- low residue diet/no standard bowel preparation, standard bowel preparation
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Hamilton Health Sciences Corporation
Splenic Flexure Mobilization
Laparoscopic Splenic Flexure Mobilization
This retrospective cohort study conducted on 140 patients who underwent laparoscopic anterior resection for upper rectal cancer in the period from May 2011 to November 2015, comparison will be done on splenic flexure mobilization…
- Trial name
- NCT03001375
- Testing
- Laparoscopic high anterior resection splenic flexure mobilization, Laparoscopic high anterior resection without splenic flexure mobilization
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Surgical Anastomosis
ICG Anastomotic Control in Digestive System Surgery
This was a parallel single-center retrospective cohort study conducted at Linglong Yingcheng Hospital, Shandong, China. The purpose of this study was to investigate the effect of indocyanine green (ICG) on patients undergoing…
- Trial name
- NCT06270745
- Testing
- indocyanine green
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shandong Linglong Yingcheng Hospital
C.Surgical Procedure; Digestive System, Symptomatic Disorders of the Gastrointestinal Tract
An International, Multicentric, Prospective, Observational Study to Evaluate Monosyn® Suture Material for Anastomoses in the Gastrointestinal Tract
The aim of this non-interventional study is to evaluate the efficacy of a monofilament, mid-term absorbable suture material (Monosyn®) for anastomosis performed in the gastrointestinal tract using the frequency of anastomosis…
- Conditions
- C.Surgical Procedure; Digestive System, Symptomatic Disorders of the Gastrointestinal Tract, Gastric Anastomosis (Site), Gastrointestinal Neoplasms
- Trial name
- PROMEGAT (NCT02080702)
- Testing
- Monosyn
- Where
- 5 sites in Malaysia, Philippines and 2 more
- Volunteers
- 106 people
- Sponsor
- Aesculap AG
Ovarian Neoplasms Malignant, Anastomotic Leak
Early Dehiscence Markers in Ovarian Cancer Surgery
EDMOCS trial pretends to evaluate if C-reactive protein (CRP) and procalcitonin (PCT) can predict intestinal anastomotic leaks before early discharge in advanced ovarian cancer surgery requiring intestinal resection.
- Trial name
- EDMOCS (NCT03131492)
- Testing
- Blood test
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Anastomotic Leaks
Surgical Intuition in Anastomotic Leakage After Colorectal Surgery
The SURGUT study aims to assess how well a computer model predicts bowel leaks after surgery. It will also examine whether adding surgeons' intuition improves these predictions.
- Trial name
- SURGUT (NCT07888478)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,300 people
- Sponsor
- University Hospital, Basel, Switzerland
Early-feeding
Jejunostomy-Based Early Enteral Feeding After Esophagectomy
Esophagectomy with reconstruction for esophageal cancer is associated with delayed gastrointestinal recovery and substantial postoperative morbidity.
- Trial name
- NCT05892263
- Testing
- early feeding
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Rectal Cancer Patients, Anastomotic Leakage
CRP/CT-Guided Selective Ileostomy After LAR
This single-center, parallel-group randomized controlled trial compared routine diverting loop ileostomy with a postoperative CRP/CT-guided selective ileostomy strategy in adults undergoing laparoscopic low anterior resection for…
- Conditions
- Rectal Cancer Patients, Anastomotic Leakage, Low Anterior Resection
- Trial name
- less stoma (NCT07722533)
- Testing
- Serial C-reactive protein-guided computed tomography surveillance and selective omission of defunctioning ileostomy, routine follow up
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Alexandria University
Left Elective Colectomy, Renal Transplanted Patients
Left Elective Colectomy in Renal Transplanted Patients
Aim of the study : To evaluate postoperative outcomes of elective left-sided colectomy in a renal transplanted population. Methods : From 2010 to 2015, all consecutive patients who underwent left elective colectomy in a referral…
- Trial name
- LECoRT (NCT04495023)
- Testing
- Left elective colectomy
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
C-Reactive Protein, Anastomotic Leak
C-protein Reactive for the Detection of Anastomotic Leakage After Surgery for Digestive Cancer
The aim of this study is to investigate the diagnostic accuracy of the C Protein Reactive (CRP) for the detection of Anastomotic leakage after surgery for digestive cancer.
- Conditions
- C-Reactive Protein, Anastomotic Leak, Digestive System Neoplasm
- Trial name
- NCT04133324
- Testing
- C-reactive protein
- Where
- Morocco
- Volunteers
- 500 people
- Sponsor
- Moroccan Society of Surgery
Rectal Neoplasms
Perfusion Outcomes With Near Infrared-Indocyanine Green Imaging System in Laparoscopic Total Mesorectal Excision for Mid- or Low-rectal CanceR
It is a multicenter, prospective, and randomized controlled clinical study of patients with mid- or low- rectal cancer who received laparoscopic TME surgery aims to explore whether the application of near infrared-indocyanine…
- Trial name
- POSTER (NCT04012645)
- Testing
- application of near infrared-indocyanine green imaging system, Non-application of near infrared-indocyanine green imaging system
- Where
- 2 sites in China
- Volunteers
- 547 people
- Sponsor
- Zhongtao Zhang
Pancreatic Cancer, Pancreatic Anastomotic Leak
Pancreaticogastrostomy Versus Pancreaticojejunostomy in Reconstruction After Cephalic Duodenopancreatectomy
Pancreaticoduodenectomy is the standards surgical procedure for various malignant and benign disease of the pancreas and periampullariy region.
- Trial name
- PanAm (NCT01324856)
- Testing
- Pancreatico gastro anastomosis, Pancreaticojejuno anastomosis
- Where
- 4 sites in Serbia
- Volunteers
- 100 people
- Sponsor
- University of Belgrade
Colorectal Cancer
Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage
Colorectal cancer (CRC) is the fourth most commonly diagnosed cancer in the world and the third in France. Its incidence is steadily rising in developing nations.
- Trial name
- FLUOCOL-1 (NCT05168839)
- Testing
- FLUO+ : Intraoperative fluorescence angiography (IOFA) with indocyanine green (ICG).
- Where
- 32 sites in France
- Volunteers
- 1,010 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Esophageal Neoplasms, Esophagectomy
Effect of Neck Flexion on Esophagogastric Anastomotic Leakage After MIE
Esophageal cancer (EC) is the eighth most common cancer and the sixth leading cause of cancer deaths worldwide. Minimally invasive esophagectomy (MIE) is regarded as a safe and effective management for resectable EC.
- Conditions
- Esophageal Neoplasms, Esophagectomy, Anastomotic Leak
- Trial name
- NCT02418052
- Testing
- neck flexion
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Anastomotic Leak Esophagus
Anastomotic Leaks in Esophageal Squamous Cell Carcinoma Patients After Trimodal Therapy
To investigate the clinical factors and preoperative treatment to the future anastomotic location of cervical esophagus that were correlated with anastomotic leaks in esophageal squamous cell carcinoma patients undergoing…
- Trial name
- NCT06556355
- Testing
- neoadjuvant chemoradiation and McKeown esophagectomy
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Qiaoqiao Li
Colo-rectal Surgery, Anastomotic Leak Large Intestine
Comparison of Rates of Anastomotic Leak in Patients Undergoing Colo-rectal Surgery When Bowel Perfusion and Resection Margin is Deterimined by Intra-operative Infra-red Thermography or by Conventional Method
Pilot RCT with 20 patients in both test and control group. In the control group resection \& anastomosis was done using the conventional method.
- Conditions
- Colo-rectal Surgery, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum
- Trial name
- NCT06180564
- Testing
- Intra-operative Infra-red thermography
- Where
- India
- Volunteers
- 43 people
- Sponsor
- Sir Ganga Ram Hospital
Rectal Disease, Sigmoid Disease
Evaluation of Intestinal Vascolarization With Indocianine Green Angiography During Rectal Resection or Left Colectomy
A randomized controlled multicenter trial on the usefulness of intraoperative angiography with indocyanine green to assess anastomosis perfusion in patients who undergo laparoscopic rectal resection or left colectomy.
- Trial name
- NCT02662946
- Testing
- ICG- angiography, No angiography
- Where
- Italy
- Volunteers
- 208 people
- Sponsor
- Scientific Institute San Raffaele
Stoma Ileostomy, Stoma Colostomy
Conventional Hand Sewn End-To-End Anastomosis Versus Side-To-Side Anastomosis for Stoma Reversal: A Prospective Study
The goal of this clinical trial is to compare approaches to enterostomy reversal by hand-sewn end-to-end anastomosis versus side-to-side anastomosis (sub-divided into hand-sewn side-to-side anastomosis and stapled side-to-side…
- Conditions
- Stoma Ileostomy, Stoma Colostomy, Anastomosis, Ileus
- Trial name
- NCT05753709
- Testing
- Hand sewn end-to-end anastomosis, Hand sewn side-to-side anastomosis, Stapled side-to-side anastomosis
- Where
- India
- Volunteers
- 38 people
- Sponsor
- Sawai Mansingh Medical College
Rectal Cancer
Selective sPlenic flExure Mobilization for Low colorEctal Anastomosis After D3 lYmph Node Dissection (Speedy Trial)
In the Low Anterior Resection of rectum for cancer, the section level of IMA and the need of SFM is still debated. The aim of this study is to explore the different impacts of high and low ligation with peeling off vascular…
- Trial name
- SpeeDy (NCT03895255)
- Testing
- Paraaortic lymph node dissection, IMA high ligation, TME, routine splenic flexure mobilization, Paraaortic lymph node dissection, IMA low ligation, TME, selective splenic flexure mobilization
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- Russian Society of Colorectal Surgeons