Clinical trials: Leakage
Septic Shock, Norepinephrine Adverse Reaction
Norepinephrine Administration Through a Midline Catheter in an Intermediate Care Unit
This is a single-center study retrospectively evaluating a local clinical routine to administer norepinephrine in midline catheters, with regard to complications and patient outcomes
- Conditions
- Septic Shock, Norepinephrine Adverse Reaction, Hypotension and Shock
- Trial name
- NCT06121115
- Testing
- Norepinephrine
- Where
- Sweden
- Volunteers
- 473 people
- Sponsor
- Region Skane
Bowel Incontinence
A Study to Evaluate the Safety, Tolerability and Effectiveness of the Renew Insert in Treating Accidental Bowel Leakage
The purpose of this study is to determine whether the use of the Renew Insert is effective, tolerable and safe in the treatment of accidental bowel leakage due to bowel incontinence.
- Trial name
- REST (NCT01475474)
- Testing
- Renew Insert
- Where
- 3 sites in United States
- Volunteers
- 97 people
- Sponsor
- Renew Medical
Cerebrospinal Fluid Leakage
Study to Evaluate the Effectivity and Safety of BIOSCAFF®H Compared to DuraGen®, in Patients Undergoing Dural Repair
Study in which the presence or absence of symptoms or any health condition is observed and recorded 30 days after a cranial surgery in which the physician places a material or graft, either BIOSCAFF®H or DuraGen®, into the skull…
- Trial name
- NCT06419855
- Testing
- Human collagen matrix graft, Bovine collagen matrix graft
- Where
- 4 sites in Mexico
- Volunteers
- 2 people
- Sponsor
- Top Health S.A.P.I DE C.V.
Urine Leakage in the Indwelling Urinary Catheterization
Urinary Leakage in the Indwelling Urinary Catheterization
In the indwelling urinary catheterization (IUC), urinary leakage may develop around the catheter in the following days of catheterization.
- Trial name
- NCT04103229
- Testing
- The use of different types and volumes of solutions to inflate the catheter balloon
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ayşe AKBIYIK
Dura Mater Nick Cut or Tear, Hemostatis
Hemopatch Performance Evaluation: A Prospective Observational Registry
To assess the clinical performance and safety of HEMOPATCH Sealing Hemostat in a post-marketing setting in cardiovascular, thoracic, urologic, neurological, and other general surgical procedures.
- Conditions
- Dura Mater Nick Cut or Tear, Hemostatis, Air Leakage, Body Fluid Leakage
- Trial name
- NCT03392662
- Testing
- Hemopatch
- Where
- 15 sites in Austria, Czechia and 3 more
- Volunteers
- 621 people
- Sponsor
- Baxter Healthcare Corporation
Colostomy
Study Evaluating a New Ostomy Appliance With Regard to Leakage, Handling and Comfort
The objective of this investigation is to evaluate leakage, handling and comfort of a new ostomy appliance compared to SenSura.
- Trial name
- NCT01243294
- Testing
- SS, SenSura
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Coloplast A/S
Postoperative Bile Leak, Focal Liver Lesions
Prevention of Bile Leakage After Liver Resection in Children
Bile leakage is a clinically important complication after liver resection in children and may require prolonged drainage, additional radiological or endoscopic procedures, or repeat surgery.
- Trial name
- NCT07867522
- Testing
- prophylactic extrahepatic biliary drainage during liver resection
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Anastomotic Leak Rectum, Rectal Cancer
Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery
Rectal cancer is one of the most frequent cancer diseases, with more than 1500 new cases per year in Denmark. Fortunately, if the tumor is discovered early, surgeons can remove the part of the intestine that is afflicted, and…
- Conditions
- Anastomotic Leak Rectum, Rectal Cancer, Anastomotic Leakage
- Trial name
- OBANORES (NCT05293054)
- Testing
- Application of autologous fibrin matrix (Obsidian)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Pain, Quality of Life
Simultaneous RZV and aIIV4 Vaccination
The overall aim of the study is to compare the safety of simultaneous Zoster Vaccine Recombinant, Adjuvanted (RZV) (SHINGRIX®) and Quadrivalent Influenza Vaccine, Adjuvanted (FLUAD®) versus simultaneous Zoster Vaccine…
- Conditions
- Pain, Quality of Life, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05007041
- Testing
- FLUAD® Quadrivalent, Fluzone® High-Dose Quadrivalent, SHINGRIX®
- Where
- 2 sites in United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Duke University
Intestinal Anastomotic Leak
Risk Factors for Anatomic Leakage in Advanced Ovarian Cancer Surgery
Cytoreductive surgery is currently the main treatment for advanced epithelial ovarian cancer (AEOC), and the complete disease removal (RT=0) or the achievement of an optimal residual disease (RT < 1 cm) remain the factors with…
- Trial name
- NCT04604964
- Testing
- Evaluation of anastomotic leakage occurrence
- Where
- Italy
- Volunteers
- 515 people
- Sponsor
- Catholic University of the Sacred Heart
Anastomotic Leak
Neutrophil-to-lymphocyte Ratio vs C-reactive Protein as Early Predictors of Anastomotic Leakage After Colorectal Surgery
Introduction: Colorectal surgery (CRS) is associated with high morbidity rates, being anastomotic leakage (AL) one of the most serious complications with an incidence as high as 15%, accounting for up to a third of mortality in…
- Trial name
- NCT04673110
- Testing
- Neutrophil to Lymphocyte Ratio and C-reactive protein
- Volunteers
- 116 people
- Sponsor
- Clinica Universitaria Reina Fabiola, Universidad Catolica de Cordoba
Contrast Media Extravasation
Study of Iodine Contrast Media Extravasation
The purpose of this study is to determine the best intervention after the extravasation of the iodinated contrast medium out of a vessel into the surrounding tissues.
- Trial name
- NCT03426735
- Testing
- Dry heat, Dry cold
- Where
- 9 sites in Spain
- Volunteers
- 65 people
- Sponsor
- Hospital de Sant Pau
Patients Undergoing PET/CT Investigation or Nuclear Medicine Therapy
New AI-based Technologies in Nuclear Medicine
The study aims to identify and predict radiopharmaceutical extravasation events using new semi-quantitative parameters and machine learning models. It involves dose rate measurements to develop metrics for real-time monitoring.
- Trial name
- AI-basedMedNuc (NCT07174089)
- Testing
- RadEye SPRD-ER device: spectrometric radiation detector capable of detecting gamma radiation.
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Bowel Perforation, Abscess
Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis
Intra-abdominal pressure(IAP) is defined as a steady state pressure of the abdominal cavity many studies have proved IAP as a prognostic factor that elevated IAP influences hemodynamics and multiple organs dysfunction In previous…
- Conditions
- Bowel Perforation, Abscess, Leakage, Peritonitis
- Trial name
- NCT01784458
- Volunteers
- 46 people
- Sponsor
- University of Ulsan
Anastomotic Leak Rectum, Rectal Cancer
Treatment of Anastomotic Leakage After Rectal Cancer Resection
The TENTACLE: Rectum study is a multinational retrospective cohort study that includes patients with anastomotic leakage after rectal cancer resection.
- Trial name
- TENTACLE:R (NCT04127734)
- Testing
- The efficacy of various interventions for anastomotic leakage after rectal cancer resection are investigated
- Volunteers
- 1,246 people
- Sponsor
- Radboud University Medical Center
Oncology, Extravasation
ivWatch in Prevention of Extravasation of Vesicants in an Oncology Setting
This study aims to determine the feasibility of using the ivWatch (registered trademark) device to determine if there is an infiltration at the site of a peripheral intravenous (PIV) catheter.
- Trial name
- NCT06758011
- Testing
- ivWatch
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- Roswell Park Cancer Institute
Anastomotic Leakage, Esophageal Cancer
Mediastinal Microdialysis in Patients With Oesophageal or Cardia Cancer Treated by Resection
Postoperative anastomotic leakage is a serious complication in patients with oesophageal or cardia cancer. Early diagnosis and treatment are mandatory.
- Trial name
- NCT00686569
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Active Noninfectious Uveitis Affecting the Posterior Segment
A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants
This study is researching an experimental drug called REGN7041 (also referred to as "study drug"). The study is focused on patients who have active inflammation inside of the eye without any signs of infection.
- Trial name
- TITAN (NCT07218770)
- Testing
- REGN7041
- Where
- 5 sites in United States
- Volunteers
- 1 people
- Sponsor
- Regeneron Pharmaceuticals
Gastroesophageal Junction Adenocarcinoma, Surgery
Gastric Microperfusion in Patients Undergoing Gastroesophageal Resections
Gastroesophageal resection because of gastroesophageal junction (GEJ) adenocarcinoma is a massive surgical intervention. Currently, gastroesophageal cancer surgery is performed with upper laparotomy followed by thoracotomy at the…
- Trial name
- NCT02077673
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Dengue Fever With Warning Signs
Clinical and Laboratory Factors for the Progression of Severe Dengue Among Hospitalized Patients During an Upsurge
Hypothesis (if any): Not applicable Objectives: To identify factors for progression to severe Dengue in hospitalized patients. Methods: Prospective Observational study
- Trial name
- PROSED (NCT06697041)
- Where
- 2 sites in Bangladesh
- Volunteers
- 324 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh