Clinical trials: Learning Disabilities, open to volunteers
Neurodevelopmental Disorders, Intellectual Disability
Longitudinal Study of Neurogenetic Disorders
The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment.
- Conditions
- Neurodevelopmental Disorders, Intellectual Disability, Developmental Delay, Autism Spectrum Disorder
- Trial name
- NCT03492060
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Columbia University
Congenital Anomalies, Development Delay
Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay
The goal of this observational cross-sectional study is to study the results of karyotyping analysis for children presented with congenital anomalies and developmental delay aged 1 month to 12 years, the need for further genetic…
- Trial name
- NCT07167017
- Volunteers
- 75 people
- Sponsor
- Assiut University
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
CTNNB1 Neurodevelopmental Syndrome
CTNNB1 Neurodevelopmental Syndrome - Natural History Study
The aim of the Dragonfly study is to characterise and monitor the neurodevelopment of children and adults diagnosed with CTNNB1 syndrome through an international collaborative effort.
- Trial name
- Dragonfly (NCT07167732)
- Testing
- A General Medical and Neurological Assessment, World Health Organisation (WHO) Motor Milestones, Burke-Fahn-Marsden Dystonia Rating Scale
- Where
- 2 sites in Australia, Slovenia
- Volunteers
- 250 people
- Sponsor
- University Medical Centre Ljubljana
Specific Learning Disabilities, Dental Caries
Dental Caries and Oral Hygiene Status in Children With Specific Learning Disabilities
This study aims to evaluate dental caries and oral hygiene status in children aged 7-12 years with specific learning disabilities (SLD) and to compare the findings with healthy children.
- Conditions
- Specific Learning Disabilities, Dental Caries, Oral Hygiene
- Trial name
- SLD-OH (NCT07611981)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Enhancing Early Language and Cognitive Development in Toddlers Through a Culturally Adapted Home-based Parent Intervention
Home-Based Language and Cognitive Intervention for Arab Toddlers in Israel
This study evaluates the effectiveness of a culturally adapted, home-based program designed to improve language and cognitive development in Arab toddlers in Israel.
- Trial name
- CAHBI-T (NCT07233525)
- Testing
- Culturally Adapted Parent-Implemented Intervention, Child Health Education Sessions
- Where
- Israel
- Volunteers
- 240 people
- Sponsor
- Hillel Yaffe Medical Center
Children, Only, Vestibular Disorder
Vestibular and Postural Function in Children Suspected of Balance Disorders
The goal of this prospective cohort study is to investigate the vestibular function in children suspected of balance disorders, and to follow up on their balance progressions after rehabilitation.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function Disorder, Development Delay
- Trial name
- VASIC (NCT06229704)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Gødstrup Hospital
Intellectual Disabilities Global Developmental Delay
Dyadic Creative Arts Therapies-based Intervention for Children With Intellectual and Developmental Disabilities
Background: Interactions between parents and children with intellectual and developmental disabilities (IDD) tend to be directive and didactic lacking in playfulness and enjoyment.
- Trial name
- NCT06541782
- Testing
- Dyadic CAT-based Intervention, Psycho-Educational Parent Counseling
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- University of Haifa
Neurologic Disorders, Autism
The Neurodevelopmental and Behavioral Phenotyping Screening Protocol
The purpose of this protocol is to allow for the careful evaluation of healthy volunteers and individuals with risk for psychiatric disorders or neurodevelopmental disorders, such as autism spectrum disorder for specific…
- Conditions
- Neurologic Disorders, Autism, Neurodegenerative Disease, Neurobehavioral Manifestation
- Trial name
- NCT00271622
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Executive Function Deficits (EFD)
Unstuck-Early Childhood Effectiveness & Implementation Trial
The goal of this clinical trial is to learn if a new school-based, Tier 2 (selective) cognitive-behavioral intervention called Unstuck and On Target for Early Childhood (Unstuck-EC) can treat executive function deficits in young…
- Trial name
- NCT07832344
- Testing
- Unstuck and On Target for Early Childhood
- Volunteers
- 90 people
- Sponsor
- Children's National Research Institute
Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD)
Single Session Support for Parents of Children With Neurodevelopmental Disabilities Struggling With Anxious Avoidance
This study will inform the development of a brief online program to help parents better understand and respond to anxiety-related behaviors in children with neurodevelopmental disorders (NDDs) such as autism spectrum disorder…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), Intellectual Disability
- Trial name
- EMPOWER-ND (NCT07898592)
- Testing
- EMPOWER-ND
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University Charles River Campus
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Stroke, Dyslexia, Acquired
Neurofeedback Intervention for Reading Deficits in Subacute Stroke
The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation.
- Trial name
- ReadingNFB (NCT04875936)
- Testing
- Motor Imagery and Real-Time fMRI Neurofeedback
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Intellectual Disabilities, Developmental Disability
Health Engagement & Access Through Learning, Training, and Health-coaching With People With Intellectual and/or Developmental Disabilities
The purpose of this study is to see if a combination of an educational curriculum and health coaching embedded within Special Olympics improves health outcomes and healthcare access compared to regular Special Olympics sport and…
- Trial name
- HEALTH 4 ME (NCT07475117)
- Testing
- Comprehensive Community Health, Regular Special Olympics programming
- Where
- United States
- Volunteers
- 1,040 people
- Sponsor
- University of Wisconsin, Madison
Cognitive Disorder, Metabolic Disease
Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency
Background: Creatine transporter deficiency (CTD) is a genetic disorder that mainly affects the brain in males. CTD causes intellectual disability that can be mild to severe.
- Conditions
- Cognitive Disorder, Metabolic Disease, Autism Spectrum Disorder
- Trial name
- NCT05600946
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder, Developmental Disabilities
A Self-Instructional Online Program for Early Childhood and Elementary Teachers Supporting Autistic Children and Children With Developmental Delays
The goal of this clinical trial is to evaluate the preliminary effectiveness and acceptability of a self-instructional, web-based teacher training program designed to support the development of autistic children and children with…
- Conditions
- Autism Spectrum Disorder, Developmental Disabilities, Developmental Delay, Teacher Training
- Trial name
- SEED (NCT07524192)
- Testing
- SEED Online Self-Instructional Program, Comparison Educational Materials (Kit for Kids)
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Boin Choi
Neurofibromatosis Type 1 (NF1), NF2-related Schwannomatosis
How Can the Experience of Hospital Outpatient Departments be Improved?
This project aims to improve outpatient departments by working with patients and staff to make these spaces more inclusive for people with sensory challenges (it focuses on people with nerve tumour conditions as they are more…
- Trial name
- NCT07818213
- Testing
- Qualitative data collection activities
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Chronic Low Back Pain
Pain Neuroscience Education Combined With Lumbar Stabilization Exercises on Disability and Kinesiophobia Among Patients With Chronic Low Back Pain
This study will investigate the effect of adding Pain Neuroscience Education (PNE) to a standard lumbar stabilization exercise program on disability and kinesiophobia among patients with chronic low back pain in the Gaza Strip.
- Trial name
- NCT07307859
- Testing
- Experimental Group - Lumbar Stabilization Exercises + PNE, Control Group - Lumbar Stabilization Exercises Only
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Learning Disabilities
Balance and Motor Skills in SLD Children
This study aimed to evaluate postural control, balance, and fine motor skills in children followed up with a diagnosis of specific learning disabilities.
- Trial name
- NCT07419477
- Testing
- -Seated Postural Control Measure, -Bruininks-Oseretsky Motor Proficiency Test (two sub-items) for balance, -Jebsen Taylor Hand Function Test (JTEFT) and 9-Hole Peg Test to assess hand function
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Bandırma Onyedi Eylül University