Clinical trials: Left Bundle Branch Block
Heart Failure, Left Bundle-Branch Block
Tailor-CRT: Better Application of Cardiac Resynchronization Therapy
Approximately one third of patients treated with cardiac resynchronization therapy (CRT) do not derive any clinical benefit. CRT response can be improved by tailoring LV lead placement and programming of atrio-ventricular (AV)…
- Trial name
- NCT02326493
- Testing
- Cardiac Resynchronization Therapy
- Where
- Netherlands
- Volunteers
- 28 people
- Sponsor
- Maastricht University Medical Center
High Degree AV-block, Left Bundle Branch Block
QT Interval in Patients With Pacemaker Dependency
The aim of this study is to examine a correction term for an adapted QT interval during ventricular pacing (right, left and biventricular pacing) to obtain valid formulae correcting for the QT intervals in various pacing…
- Trial name
- QT-TENDENCY (NCT01694550)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Magdeburg
Left Bundle Branch Block, Transcatheter Aortic Valve Replacement
HV Electrophysiology Study In Transcatheter Aortic Valve Implantation Patients
TAVI induced LBBB is a complication that occurs between 7 and 65 % of the cases, numbers that differ considerably between devices.
- Conditions
- Left Bundle Branch Block, Transcatheter Aortic Valve Replacement, Transcatheter Aortic Valve Implantation
- Trial name
- HESITATE (NCT02659137)
- Testing
- HV measurement
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Left Bundle Branch Block
Left Bundle Branch Block ECG Characteristics in the Evaluation of Acute Coronary Syndrome
Purpose of the study: The goal of this study is to evaluate the relationship of electrocardiogram (ECG) findings with clinical outcomes in a cohort of patients with left bundle branch block (LBBB) who are being evaluated for…
- Trial name
- NCT02283619
- Testing
- None - no intervention, observational study
- Volunteers
- 8 people
- Sponsor
- Duke University
Heart Failure, Systolic, Left Bundle Branch Block
Optimal Coronary Sinus Lead Implantation Using Intracardiac Impedography and Magnetic Resonance Imaging
Despite the dramatic effect of cardiac resynchronization therapy (CRT) on survival and morbidity in people with congestive heart failure, 50-70% of eligible patients do not respond to this intervention.
- Trial name
- NCT01129635
- Testing
- Cardiac Resynchronization Therapy (CRT) implantation
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Emory University
Congestive Heart Failure, Left Bundle Branch Block
MADIT ASIA Cardiac Resynchronization Trial
The purpose of this trial or study is to determine if pacemaker therapy can be a beneficial alternative to conventional medical therapy in patients with a history of moderate heart failure.
- Conditions
- Congestive Heart Failure, Left Bundle Branch Block, Heart Failure, Systolic
- Trial name
- MADIT-ASIA (NCT01872234)
- Testing
- Two-lead CRT-P
- Where
- 21 sites in China, India and 6 more
- Volunteers
- 1 people
- Sponsor
- Boston Scientific Corporation
Heart Failure, Reduced Left Ventricular Ejection Fraction
EP-Catheter Guided CS-Lead Implantation
In patients undergoing CRT device implantation a lead positioning in the coronary sinus is required. Even this part of the surgical procedure is challenging.
- Conditions
- Heart Failure, Reduced Left Ventricular Ejection Fraction, Left Bundle Branch Block
- Trial name
- NCT01922544
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Cologne
Heart Failure, Left Bundle Branch Block
High Septal Pacing for Cardiac Resynchronization Therapy
The purpose of this acute study is to perform a preliminary investigation of high septal right ventricular pacing in the vicinity of the His bundle region as an alternate or adjunctive means for cardiac resynchronization in…
- Conditions
- Heart Failure, Left Bundle Branch Block, Heart Disease
- Trial name
- HISTORY (NCT01325480)
- Testing
- Cardiac Pacing
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Boston Scientific Corporation
Heart Failure, Left Bundle-Branch Block
Resynchronization in Paced Heart Failure Patients With Implantable Cardioverter Defibrillator (ICD) Indication
Today patients with a Cardiac Resynchronization Therapy (CRT) indication usually receive 2 ventricular leads, right ventricular (RV) apex and left ventricular (LV) (postero-) lateral, gaining a responder rate of approximately…
- Trial name
- CRTICD Dual LV (NCT01415024)
- Testing
- second LV lead in CRT
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Schuechtermann-Klinik