Clinical trials: Left Side
Vascular Retinopathy of Left Eye (Disorder), Vascular Retinopathy of Right Eye (Disorder)
Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy
The study used a new surgical technique: intraoperative fluorescence imaging,In the 1980s, some scholars proposed the concept of intraoperative fluorescein angiography.During vitrectomy, intraoperative fluorescein angiography…
- Conditions
- Vascular Retinopathy of Left Eye (Disorder), Vascular Retinopathy of Right Eye (Disorder), Diabetic Retinopathy, Retinal Vein Occlusion
- Trial name
- NCT06343961
- Testing
- Intraoperative Fluorescein Angiography
- Volunteers
- 80 people
- Sponsor
- Jie Zhong
Rotator Cuff Tears, Rotator Cuff Injuries
Clinical Outcomes Related to Arthroscopic Rotator Cuff Repair Recovery Using Incrediwear
To assess the benefits of using the Incrediwear products for patients recovering from Arthroscopic Rotator Cuff Repair surgery for postoperative pain, range of motion, and swelling.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Arthropathy of Left Shoulder (Disorder), Rotator Cuff Arthropathy of Right Shoulder (Disorder)
- Trial name
- NCT06669741
- Testing
- Shoulder Sleeve
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Sleep Apnea, Central, Ventricular Dysfunction
Benefit of One Month Zopiclone Intake on Adaptative Servoventilation Compliance
The study evaluate the effect of adaptative servoventilation (ASV) initiation combined with 14 days Zopiclone vs Placebo treatment in patients with central sleep apnea (CSA) syndrome.
- Trial name
- ZODIAC (NCT02820441)
- Testing
- Zopiclone
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Grenoble
Coronary Artery Disease
MIDCAB Versus DES in Proximal LAD Lesions
Percutaneous coronary intervention with a sirolimus-coated stent compared to minimally invasive bypass surgery in patients with isolated proximal left anterior descending coronary arteries in terms of non-inferiority of an end…
- Trial name
- NCT00299429
- Testing
- Stenting and minimally invasive bypass surgery, PCI with DES
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University of Leipzig
End Stage Renal Disease / Hemodialysis
Mineralocorticoid Receptor Antagonists in End Stage Renal Disease
End stage renal disease (ESRD) patients exhibit an extraordinarily high annual mortality. Cardiovascular (CV) causes account for almost half of all-cause mortality.
- Trial name
- MiREnDa (NCT01691053)
- Testing
- Spironolactone
- Where
- 3 sites in Germany
- Volunteers
- 118 people
- Sponsor
- Wuerzburg University Hospital
Heart Failure
Effects of Sacubitril/Valsartan on Exercise Capacity, Natriuretic Peptides and Ventricular Remodeling in Heart Failure
Background: Sacubitril/valsartan, a novel therapy in the treatment of heart failure with reduced ejection fraction (HFrEF), has recently proved efficacy in improving exercise tolerance and cardiac performance.
- Trial name
- NCT04434170
- Testing
- Sacubitril-Valsartan
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- Centro Cardiologico Monzino
Congenital Heart Disease, Cyanotic Congenital Heart Disease
Prenatal Maternal Mental Health and Neurodevelopment in Congenital Heart Disease
Congenital heart disease (CHD) is the leading cause of congenital malformations, representing 1% of live births. Progress in surgical care have led to the dramatic increase in the population of children and adults living with…
- Conditions
- Congenital Heart Disease, Cyanotic Congenital Heart Disease, d-Transposition of the Great Arteries, Hypoplastic Left Heart Syndrome
- Trial name
- Neuro-Moms (NCT06711666)
- Where
- 5 sites in France
- Volunteers
- 174 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Diabetes Mellitus Type 2
SGLT2 Inhibition and Left Ventricular Mass
Patients with type 2 diabetes mellitus are exposed to an excessive heart failure risk secondary to left ventricular hypertrophy and impaired diastolic filling, a condition not addressed by currently available treatments.
- Trial name
- EMPATROPHY (NCT02728453)
- Testing
- Empagliflozin, Glimepiride
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Hannover Medical School
Obstructive Sleep Apnea
The Continuous Positive Airway Pressure Effect on Rho-associated Coiled-coil Containing Kinases Activity.
The ROCK (Rho-associated coiled-coil containing kinases) play a critical role in the pathogenesis of cardiovascular diseases and left ventricle hypertrophy (LVH).
- Trial name
- NCT05014529
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pulmonary Disease, Chronic Obstructive
Cardiovascular Function in COPD Patients
The objectives of the study are to explore the effect of treatment with tiotropium + olodaterol fixed dose combination (FDC) compared to fluticasone propionate + salmeterol FDC on: reversal of left ventricular diastolic…
- Trial name
- NCT03055988
- Testing
- Tiotropium, Olodaterol, Fluticasone propionate
- Where
- 10 sites in Germany
- Volunteers
- 76 people
- Sponsor
- Boehringer Ingelheim
Colon Cancer, Rectal Cancer
Stoma Closure and Reinforcement Trial
Hernia formation at sites of ostomy closure is a common complication. The investigator believes that using evidence based hernia repair techniques as a preventive measure during closure of ostomies will reduce the incidence of…
- Conditions
- Colon Cancer, Rectal Cancer, Ileostomy - Stoma
- Trial name
- SCAR (NCT03750461)
- Testing
- Mesh Implantation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Atrial Fibrillation and Other Dysrhythmias | Patient
French Database of Left Atrial Appendage Closure
Patients with atrial fibrillation are exposed to a high risk of thrombus in the left atrium that can induce cerebral vascular events or systemic embolisms.
- Trial name
- FLAAC (NCT02252861)
- Testing
- Percutaneous Left Atrial Appendage Closure in routine care
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Henri Mondor University Hospital
Three Vessel Coronary Artery Disease
Association of Carotid Arterial Circumferential Strain With Left Ventricular Function and Hemodynamic Compromise During Off-pump Coronary Artery Bypass Surgery
This study is aimed to evaluate the association of common carotid artery circumferential strain with the echocardiographic parameters of left ventricular function and the degree of actual hemodynamic deterioration in patients…
- Trial name
- NCT01840969
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Yonsei University
Left Ventricular Assist Device
Exercise Tolerance in Patients With Implanted Left Ventricular Assist Device
To evaluate the concept of dynamic pump speed optimization based on the echocardiographic assessment of aortic valve opening during cardiopulmonary exercise test.
- Trial name
- NCT05063006
- Testing
- Cardiopulmonary exercise tests with maintained baseline optimal pump speed settings., Cardiopulmonary exercise test with gradually increased pump speed depending on live echocardiographic imaging.
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Karol Wierzbicki
Heart Failure, Cardiac Pacing, Artificial
Acute Effects of LBBP Versus BVP for CRT
The study was designed to compare the acute effects of left bundle branch pacing (LBBP) with biventricular pacing (BVP) in patients with left ventricular ejection fraction (LVEF) <=35% with left bundle branch block (LBBB).
- Conditions
- Heart Failure, Cardiac Pacing, Artificial, Cardiac Resynchronization Therapy
- Trial name
- NCT04505384
- Testing
- left bundle branch pacing, biventricular pacing
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Shanghai Zhongshan Hospital
Hypertrophic Cardiomyopathy
Role of Perhexiline in Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy (HCM) is the most common inherited heart muscle condition affecting up to 1 in 200 of the general population.
- Trial name
- RESOLVE-HCM (NCT04426578)
- Testing
- Perhexiline
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Flinders University
Persisent Atrial Fibrillation, Reversal of Atrial Enlargement
Left Atrial Volume Changes Who Underwent Cardioversion and Recurrence of AF After RF Ablation in Persistent AF (SAFE-AF)
Electrical/pharmacological cardioversion improves structural remodeling of left atrium. We hypothesize that persistent atrial fibrillation (AF) patients with more significant left atrial size reduction after cardioversion have…
- Conditions
- Persisent Atrial Fibrillation, Reversal of Atrial Enlargement, Recurrence of Atrial Fibrillation
- Trial name
- SAFE-AF-ABL (NCT06523738)
- Testing
- 1. electrical/pharmacological cardioversion. 2.pulmonary vein isolation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Heart Failure, Photoplethysmography
Seerlinq: Non-invasive LVFP Monitoring in HF
Left ventricular filling pressure (LVFP) monitoring has been associated with improved quality of life, survival and reduced hospitalization rates.
- Conditions
- Heart Failure, Photoplethysmography, Right Heart Catheterization
- Trial name
- PPG-HF (NCT06649435)
- Testing
- PPG measurement
- Where
- Slovakia
- Volunteers
- 131 people
- Sponsor
- Seerlinq s. r. o.
Type 2 Diabetes, Heart Failure
Optimized Glycemic Control in Heart Failure Patients With DM2:"Effect on Left Ventricular Function and Skeletal Muscle"
The investigators wish to investigate wether a more strict diabetic control improves cardiac function, muscle strength, exercise capacity and decreases symptoms.
- Trial name
- HFDM (NCT01213784)
- Testing
- all antidiabetic drugs will be appliable
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Atrial Fibrillation
Continued Access to PREVAIL (CAP2) - WATCHMAN Left Atrial Appendage (LAA) Closure Technology
To provide additional information about the safety and efficacy of the WATCHMAN LAA Closure Technology
- Trial name
- CAP2 (NCT01760291)
- Testing
- WATCHMAN LAA Closure Technology
- Where
- 3 sites in United States
- Volunteers
- 576 people
- Sponsor
- Boston Scientific Corporation
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