Clinical trials: Left Side
Pterygium of Right Eye, Pterygium of Left Eye
Comparison of Recurrence Between Mini-SLET and Limbal-Conjunctival Autograft Techniques in Primary Pterygium
The surgical treatment options for pterygium, an abnormal growth on the eye's frontal surface can be treated with several surgical techniques.
- Conditions
- Pterygium of Right Eye, Pterygium of Left Eye, Pterygium of Both Eyes, Pterygium
- Trial name
- NCT06402643
- Testing
- Pterygium Excision
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Radiation Cystitis, Non-valvular Atrial Fibrillation
Study of the Effects of Anticoagulant Interruption Covered by Percutaneous Left Atrial Occlusion in Patients With Chronic Atrial Fibrillation and Radiation Cystitis at Risk of Bleeding
The etiology of the radiation cystitis is a pelvic irradiation generally performed as part of the treatment of prostate cancer. The incidence is 50,000 new cases per year.
- Trial name
- HEMOCC (NCT04701749)
- Testing
- Percutaneous left atrial closure, No Percutaneous left atrial closure
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Fabry Disease
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
This is an 18-month, multicenter, randomized, active-control, parallel-group Phase 3 study, in which participants will be randomized to venglustat versus standard of care therapy (agalsidase alfa, agalsidase beta, or migalastat)…
- Trial name
- CARAT (NCT05280548)
- Testing
- Venglustat (GZ402671), Agalsidase alfa, Agalsidase beta (GZ419828)
- Where
- 54 sites in United States, Austria and 17 more
- Volunteers
- 104 people
- Sponsor
- Sanofi
Heart Failure, Cardiac Resynchronization Therapy
LVSP Based CRT vs. RVAP Based CRT
To find out whether left ventricular septal pacing (LVSP)-based cardiac resynchronization therapy (CRT) is superior to right ventricular apical pacing (RVAP)-based CRT in patients with failed left bundle branch pacing at the…
- Conditions
- Heart Failure, Cardiac Resynchronization Therapy, Left Ventricular Septal Pacing, Right Ventricular Septal Pacing
- Trial name
- NCT05985408
- Testing
- left ventricular septal pacing, right ventricular apical pacing
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fu Wai Hospital, Beijing, China
Chronic Dialysis in Children
Dietary Sodium Intake in Children on Chronic Dialysis
Cardiovascular disease is common in patients with end-stage renal disease that began in childhood, and volume overload plays a key role in the development of hypertension, left ventricular hypertrophy (LVH) and alterations.
- Trial name
- PeDialysis (NCT06165640)
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Strasbourg, France
Efficacy, Self, Safety Issues
I Can sEe Left Atrial Appendage (ICELAA) Clinical Study
The primary objective of this study is to assess the efficacy and safety of using intra-procedural intracardiac echocardiography (ICE) for WATCHMAN FLX Device implants in subjects with non-valvular atrial fibrillation to reduce…
- Trial name
- ICELAA (NCT04196335)
- Testing
- intra-procedural intracardiac echocardiography
- Where
- 7 sites in Denmark, Italy and 2 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Asymptomatic Left Ventricular Systolic Dysfunction (Disorder), Heart Failure
ECG AI-Guided Screening for Low Ejection Fraction
This is a randomized controlled trial (RCT) to test a novel artificial intelligence (AI)-enabled electrocardiogram (ECG)-based screening tool for improving the diagnosis and management of left ventricular systolic dysfunction.
- Trial name
- EAGLE (NCT04000087)
- Testing
- AI-enabled ECG-based Screening Tool
- Where
- United States
- Volunteers
- 358 people
- Sponsor
- Mayo Clinic
Heart Failure
Evaluation of the Jarvik 2000 Left Ventricular Assist System With Post-Auricular Connector--Destination Therapy Study
This investigation will be conducted as an interventional intention-to-treat clinical study in a population of end stage heart failure patients who meet specific inclusion and exclusion criteria.
- Trial name
- NCT01627821
- Testing
- Jarvik 2000 VAS, HeartMate II
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Jarvik Heart, Inc.
Radiation Exposure
Hyper Adduction of Right Radial Artery/Arm vs Left Drag Over Technique
Several studies have shown that operator exposure via left transradial catheterization has yielded less operator exposure compared to standard right transradial procedure.
- Trial name
- HARRA (NCT05833516)
- Testing
- Cardiac Catheterization
- Where
- United States
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Risk Factors for Mortality in Cases of Obstructed Left Colonic Carcinoma
Risk Factors for Mortality in Cases of Obstructed Left Colonic Carcinoma
seeking to identify risk factors leading to mortality in obstructed left cancer colon
- Trial name
- NCT04823416
- Testing
- Resection, Stoma
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University
Complication of Surgical Procedure
Factors Responsible for the Effectiveness of the Lund De-airing Technique
The Lund de-airing technique is employed for cardiac de-airing in open left heart surgery. It consists of two main elements namely, opening of both pleura after the patient is on CPB (cardiopulmonary bypass)and disconnection of…
- Trial name
- NCT01757704
- Testing
- Open pleurae & conventional filling of heart, Intact pleurae & staged filling of heart
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Lund University
Coronary Diseases, Left Main Coronary Artery Disease
Clinical Efficacy and Safety of a Prospective, Multicenter Drug Coated Balloon for Left Main Artery Disease in China
This is a prospective and observational study. Patients with primary mediana 010 or 001 left main bifurcation lesions were treated with drug ball coated balloon from November 2018 to November 2020 in four hospitals in Huaihai…
- Conditions
- Coronary Diseases, Left Main Coronary Artery Disease, Bifurcation Lesions
- Trial name
- NCT04641468
- Testing
- DCB
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuzhou Third People's Hospital
HF - Heart Failure
AI ECG Algorithm for Detecting LV Systolic Dysfunction
This prospective observational cohort study aims to evaluate the clinical performance of a deep learning-based electrocardiography (ECG) algorithm (DeepECG LVSD) for detecting left ventricular systolic dysfunction (LVSD), defined…
- Trial name
- NCT07636759
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Ajou University School of Medicine
Atrial Fibrillation
EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography
This is a 2- component, single center study, witch aims to evaluate the efficacy of multisite intracardiac echocardiography (mICE) imaging of left atrial appendage (LAA) and in detecting thrombus located in LAA as compared to…
- Trial name
- ActionICE (NCT01371279)
- Testing
- Intra-Cardiac Echocardiography guided atrial fibrillation ablation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Centre of Postgraduate Medical Education
Pulmonary Hypertension Due to Left Heart Disease
Telemonitoring to Treat Group 2 Pulmonary Hypertension
This study aims to decrease elevated pressure in the lungs of patients with pulmonary hypertension from left heart with elevated pulmonary vascular resistance by utilizing aggressive fluid management with ReDS Pro System and…
- Trial name
- RECAPTURE (NCT04882774)
- Testing
- Treprostinil Diolamine
- Where
- 3 sites in United States
- Sponsor
- Mardi Gomberg -Maitland MD, MSc
Left Ventricular Thrombus
Apixaban Versus Warfarin for Left Ventricular Thrombus
Left ventricular thrombus is a blood clot that forms in the left ventricle and is associated with risk of systemic embolism and ischemic stroke.
- Trial name
- APEX (NCT07709780)
- Testing
- Apixaban, Warfarin
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- University of Arizona
Congenital Disorders
Predictors for Pulmonary Valve Replacement - Anatomic and Hemodynamic Using MRI
Magnetic Resonance Imaging (MRI) is a non-invasive test that can look at the heart without using radiation. An MRI will allow the doctors to look at the heart in order to assess how well the ventricle is pumping, the amount of…
- Trial name
- NCT00489788
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Emory University
Left Bundle-Branch Block, Aortic Stenosis
Study on Heart Block Risks Using Outcome-Based Modeling
This study developed a prediction model for high-grade atrioventricular block (AVB) and complete left bundle branch block (CLBBB) following transcatheter aortic valve replacement (TAVR) in Chinese patients with aortic stenosis…
- Trial name
- SAVIOR (NCT07065123)
- Testing
- The population undergoing TAVR for aortic valve stenosis with outcomes of permanent pacemaker implantation and complete left bundle branch block after surgery
- Volunteers
- 112 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hypertrophy, Left Ventricular
The CLEVER Study - Coreg And Left Ventricular Mass Regression
This study is designed to compare the effects of COREG MR (carvedilol modified release formulation) to atenolol on indices of left ventricular dimensions when added to standardized angiotensin converting enzyme (ACE) inhibition…
- Trial name
- NCT00108082
- Testing
- carvedilol MR, atenolol, lisinopril
- Where
- 78 sites in United States
- Volunteers
- 287 people
- Sponsor
- GlaxoSmithKline
Heart Failure
V-LAP™ Left Atrium Monitoring systEm for Patients With Chronic sysTOlic & Diastolic Congestive heaRt Failure
The purpose of the trial is to evaluate the safety, usability and performance of the V-LAP™ System in adult subjects with New York Heart Association (NYHA) Class III Heart Failure.
- Trial name
- VECTOR-HF (NCT03775161)
- Testing
- V-LAP™ System
- Where
- 2 sites in Germany, Italy
- Volunteers
- 45 people
- Sponsor
- Vectorious Medical Technologies Ltd.
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