Clinical trials: Left Side
Heart Failure, Photoplethysmography
Seerlinq: Non-invasive LVFP Monitoring in HF
Left ventricular filling pressure (LVFP) monitoring has been associated with improved quality of life, survival and reduced hospitalization rates.
- Conditions
- Heart Failure, Photoplethysmography, Right Heart Catheterization
- Trial name
- PPG-HF (NCT06649435)
- Testing
- PPG measurement
- Where
- Slovakia
- Volunteers
- 131 people
- Sponsor
- Seerlinq s. r. o.
Ultra-High Power Ablation,Safety of Atrial Fibrillation Ablation
Clinical Study on the Risk of Left Atrial POP Ablation and Esophageal Injury Under Ultra-High Power and Related Influencing Parameters
This study aims to evaluate the risks of steam pop (POP) and esophageal injury, as well as related influencing parameters, under ultra-high power ablation technology.
- Trial name
- UHP-POP-ESO (NCT06699368)
- Testing
- The ultra-high-power ablation group, The high-power ablation group
- Volunteers
- 120 people
- Sponsor
- The Third People's Hospital of Chengdu
Left Ventricular Ejection Fraction, Heart Failure (HF)
REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)
Primary Objective - To determine if implantation of a permanent CRT pacing device (with LB-CRT, or conventional BiV-CRT with a coronary sinus LV lead) can improve electromechanical function, HF symptoms, and natriuretic peptide…
- Conditions
- Left Ventricular Ejection Fraction, Heart Failure (HF), Left Bundle-Branch Block
- Trial name
- REINVENT (NCT05652218)
- Testing
- LB-CRT, BIV-CRT
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Inova Health Care Services
Transcranial Direct Current Stimulation, Parkinson Disease
An Open-label Study on the Clinical Efficacy of tDCS Intervention in PD
To demonstrate that intervention targeting the primary motor area (M1) using transcranial Direct Current Stimulation can improve sleep symptoms in patients with Parkinson's disease.
- Conditions
- Transcranial Direct Current Stimulation, Parkinson Disease, Primary Left Motor Cortex
- Trial name
- NCT06566313
- Testing
- transcranial Direct Current Stimulation
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Anhui Medical University
Obesity
Left Cardiac Chambers Size in Obese Individuals and Its Relation to BMI and Waist Circumference
Aim of study: To determine if there is relation between left cardiac chambers size ,BMI and waist circumference in obese individuals. 1.
- Trial name
- NCT06127082
- Testing
- Echocardiography
- Volunteers
- 200 people
- Sponsor
- Assiut University
End-stage Heart Failure, Left Ventricular Assist Device
LVAD Index and Clinical Outcomes in Continuous-Flow LVAD Patients
This single-center, observational study evaluated the LVAD index, defined as device-estimated pump flow divided by body surface area, in adult patients supported with continuous-flow left ventricular assist devices.
- Conditions
- End-stage Heart Failure, Left Ventricular Assist Device, Mechanical Circulatory Support
- Trial name
- LVAD-INDEX (NCT07633535)
- Testing
- HeartWare Ventricular Assist Device, HeartMate 3 Left Ventricular Assist Device
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gaziantep City Hospital
Non-ischemic Cardiomyopathy, DCM - Dilated Cardiomyopathy
DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies
The DZHK TranslatiOnal Registry for CardiomyopatHies (DZHK TORCH) represents a unique resource of clinical data and high quality biological samples to enable innovative clinical and molecular studies on cardiomyopathies (CMP).
- Conditions
- Non-ischemic Cardiomyopathy, DCM - Dilated Cardiomyopathy, HCM - Hypertrophic Cardiomyopathy, HOCM - Hypertrophic Obstructive Cardiomyopathy
- Trial name
- TORCH-Plus (NCT04265040)
- Where
- Germany
- Volunteers
- 2,040 people
- Sponsor
- University Hospital Heidelberg
Shock, Cardiogenic
Clinical Outcomes and Efficacy of Left Ventricular Assist Device for Korean Patients With Cardiogenic Shock
Retrospectively and prospectively enrolled patients with cardiogenic shock in domestic manifolds and investigated the current state of treatment and clinical features of cardiogenic shock in Koreans and identified the factors…
- Trial name
- SMART-RESCUE (NCT02985008)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Jeong Hoon Yang
Acute Heart Failure, COPD Exacerbation
Valsalva Manœuvre in the Diagnosis of Left Ventricular Failure in Chronic Obstructive Pulmonary Disease Exacerbation
Left ventricular failure (LVF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis .
- Trial name
- NCT01619540
- Testing
- Valsalva maneuver
- Where
- 4 sites in Tunisia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Neoplasm, Liver
Open Versus Laparoscopic Left-sided Hepatectomy Trial
Open versus Laparoscopic Left-sided Hepatectomy (OLLEH) trial Multi-institutional, prospective and randomized trial in patients undergoing left sided hepatectomy through laparoscopic versus open procedure.
- Trial name
- OLLEH (NCT03010085)
- Testing
- Open left-sided hepatectomy, Laparoscopic left-sided hepatectomy
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Cardiomyopathy
Characterization of Sympathetic Nerve Activity in Stress Cardiomyopathy
Stress (Takotsubo) cardiomyopathy (SC) is a peculiar form of acute, reversible myocardial dysfunction predominantly affecting the apical and mid left ventricular segments.
- Trial name
- NCT01048125
- Testing
- Sympathetic Nerve Activity, Mental Stress Test (Color Word Test), The Modified Oxford Technique for Baroreflex Sensitivity
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Atrial Fibrillation, Hypertension
AF Ablation With or Without ROX Coupler Study
The study will test the hypothesis that ablation of paroxysmal atrial fibrillation in hypertensive subjects is more effective when a ROX coupler is inserted concurrently.
- Trial name
- LAAPITUP3 (NCT02243891)
- Testing
- Atrial fibrillation ablation, ROX Coupler insertion
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Neil Sulke
Myocardial Infarction, Diabetes Mellitus, Type 2
SGLT2 Inhibitors on Clinical Outcomes and Left Ventricular Remodeling in Type 2 Diabetic Patients with Acute Myocardial Infarction, a Prospective, Multi-center Registry Study
Prospective trials performed on type 2 diabetes patients without established cardiovascular disease has shown that SGLT2 inhibitors reduce cardiovascular risk.
- Trial name
- RECORD-AMI (NCT05770687)
- Testing
- SGLT2 inhibitor
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Kiyuk Chang
Cardiac Output
The Effect of Left Uterine Displacement on Parturient Cardiovascular System
The aim of the study is to investigate the effect of different angles of lateral tilt on the maternal hemodynamics before and after spinal anesthesia
- Trial name
- NCT02828176
- Testing
- electric cardiometry, IV line insertion, spinal anesthesia ( subarachnoid block )
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypertension, Prehypertension
EMPower: Electronic Media Powering Positive Health Changes in Youth
The purpose of this study is to evaluate the effectiveness of a technology-based behavioral Healthy Lifestyle intervention on adiposity (body mass index z-score), blood pressure (mean clinic systolic BP), and heart size (LVM) in…
- Conditions
- Hypertension, Prehypertension, Overweight, Obesity
- Trial name
- NCT02444689
- Testing
- Electronic Media Application, Standard of care education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Johns Hopkins University
Hypertrophic Obstructive Cardiomyopathy
Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy
The primary purpose of this study is to evaluate the feasibility, the safety and the efficacy of the transapical beating-heart septal myectomy for the treatment of hypertrophic obstructive cardiomyopathy.
- Trial name
- NCT05332691
- Testing
- Transapical beating-heart septal myectomy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiang Wei
Atrial Fibrillation, Atrial Fibrillation, Persistent
Left Roof Linear, Mitral Isthmus Linear and Left Anterior Septal Linear Ablation for Non-paroxysmal AF: PROMISED Trial.
The purpose of this prospective randomized study is to assess whether a new treatment strategy consisting of circumferential Pulmonary vein isolation (PVI), left ROof linear (RL), Mitral Isthmus linear (MIL), and left anterior…
- Trial name
- NCT06249347
- Testing
- PROMISED, CPVI and LAAC, Radiofrequency ablation catheter
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Chronic Hand Dermatitis
Comparison Study With E-DO in Chronic Hand Dermatitis
The objective of this study is to evaluate the topical E-DO in patients with Chronic Hand Dermatitis (fu kuei shou).
- Trial name
- NCT00556855
- Testing
- E-DO
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- HenKan Pharmaceutical Co., Ltd.
Eustachian Tube Dysfunction, Eustachian Tube Dysfunction of Left Ear
Tympanostomy Tubes Versus Eustachian Tube Dilation
The objective of this study is to determine whether tympanostomy with pressure equalization tube placement or Eustachian tube (ET) dilation is superior at reducing symptoms of patients with ET dysfunction.
- Conditions
- Eustachian Tube Dysfunction, Eustachian Tube Dysfunction of Left Ear, Eustachian Tube Dysfunction of Right Ear (Diagnosis), Eustachian Tube Dysfunction of Both Ears (Diagnosis)
- Trial name
- NCT03886740
- Testing
- Reducing symptoms of Eustachian tube dysfunction
- Sponsor
- Columbia University
Hypoplastic Left Heart Syndrome
Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome
This is a Phase I study to determine the safety and feasibility of injections of autologous umbilical cord blood (UCB) cells into the right ventricle of Hypoplastic Left Heart Syndrome (HLHS) children undergoing a scheduled Glenn…
- Trial name
- NCT01883076
- Testing
- autologous cell-based delivery
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Timothy J Nelson, MD, PhD
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