Clinical trials: Left Side
Sudden Cardiac Arrest, Ventricular Arrythmia
Improve Sudden Cardiac Arrest Study
The purpose of this study is to demonstrate that primary prevention patients with one or more additional risk factors (1.5 prevention criteria: syncope/pre-syncope, non-sustained ventricular tachycardia (NSVT), frequent…
- Trial name
- NCT02099721
- Testing
- ICD or CRT-D Device
- Where
- 93 sites in Argentina, Belarus and 14 more
- Volunteers
- 4,222 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome, Right/Left Judgement
The discrimination of the right/left side of the body is related to the integrity of the motor and somatosensory areas at the cortical and subcortical levels.
- Trial name
- NCT04967144
- Testing
- Nerve conduction study, Montreal Cognitive Assessment Test
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Heart Failure
Safety and Efficacy Study of the QuickFlex Micro Model 1258T Left Heart Pacing Lead
This is a prospective, multi-center non-randomized clinical study to evaluate the safety and efficacy of the QuickFlex Micro Model 1258T left ventricular lead in a heart failure patient population.
- Trial name
- NCT00763698
- Testing
- QuickFlex Micro Model 1258T Left Heart Lead
- Where
- 13 sites in United States
- Volunteers
- 86 people
- Sponsor
- Abbott Medical Devices
Sodium-glucose Cotransporter 2, Inhibitors
Impact of Sodium Glucose Co-transporter 2-Inhibitors on Clinical Outcome and Left Ventricular Function in Patients Presented by Acute Myocardial Infarction
This study aimed to assess the effect of adding sodium glucose co-transporter two inhibitors on clinical outcome and left ventricular function in patients with acute myocardial Infarction.
- Conditions
- Sodium-glucose Cotransporter 2, Inhibitors, Clinical Outcome, Left Ventricule
- Trial name
- NCT06964607
- Testing
- Sodium-glucose cotransporter-2 Inhibitors, Conventional treatment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Ventricular Tachycardia, End-stage Heart Failure
Ventricular Tachycardia Ablation in LVAD Patients
The CHANNELED-Registry is a multicenter retrospective study to (1) systematically assess the mechanism and origin of ventricular tachycardia in patients with end-stage heart failure carrying an left ventricular assist device…
- Conditions
- Ventricular Tachycardia, End-stage Heart Failure, Ventricular Arrythmia, LVAD (Left Ventricular Assist Device)
- Trial name
- CHANNELED (NCT06063811)
- Testing
- Ablation
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Köln
Atrial Remodeling, Myocardial Dysfunction
Personalised Prospective Comparison of ARni With ArB in Patients With Natriuretic Peptide eLEvation
Sacubitril-valsartan, an Angiotensin Receptor Blocker-Neprilysin Inhibitor (ARNI), currently marketed for the management of heart failure, has been shown to reduce cardiovascular morbidity and mortality in stage C heart failure…
- Conditions
- Atrial Remodeling, Myocardial Dysfunction, Left Ventricular Remodeling, Left Ventricular Diastolic Dysfunction
- Trial name
- PARABLE (NCT04687111)
- Testing
- Sacubitril-Valsartan, Valsartan
- Where
- 2 sites in Ireland
- Volunteers
- 250 people
- Sponsor
- Mark Ledwidge
Left Ventricular Remodeling, Acute Myocardial Infarction
Sodium Tanshinone IIA Sulfonate in Left Ventricular Remodeling Secondary to Acute Myocardial Infarction
Approximately 60 patients with ST-segment elevation myocardial infarction successfully treated with primary percutaneous coronary intervention will be enrolled and randomized to receive the sodium tanshinone IIA sulfonate in…
- Trial name
- NCT02524964
- Testing
- sodium tanshinone IIA sulfonate, control
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Heart Failure With Reduced Ejection Fraction, Pulmonary Hypertension
Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure
Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonary hypertension (PH), yet the investigators fall short in trying to…
- Conditions
- Heart Failure With Reduced Ejection Fraction, Pulmonary Hypertension, Right Heart Failure Due to Left Heart Failure
- Trial name
- HALT-RHF (NCT06299436)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases, Electrocardiogram: Electrical Alternans
Gated SPECT Abnormality With J Point Elevation
The investigators present an interesting co-incidence of Gated wall abnormality in the inferolateral wall in normal sestamibi myocardial perfusion images with J wave in the inferior derivations of the ECG in a patient.
- Conditions
- Cardiovascular Diseases, Electrocardiogram: Electrical Alternans, Myocardial Ischemia, Early Repolarization Syndrome
- Trial name
- NCT03472898
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Ankara Education and Research Hospital
Permanent Atrial Fibrillation, Preserved Ejection Fraction
Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation Trial
The goal of this clinical trial is to learn whether left bundle branch area pacing, a technique designed to activate the heart's natural electrical conduction system, is better than conventional right ventricular pacing in adults…
- Trial name
- BEAT (NCT07759700)
- Testing
- LBBA pacing, Conventional pacing
- Where
- France
- Volunteers
- 642 people
- Sponsor
- Poitiers University Hospital
Covid19, Left Ventricular Dysfunction
Cardiac Dysfunction in Critically Ill Patients With COVID-19
Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients infected with COVID-19.
- Conditions
- Covid19, Left Ventricular Dysfunction, Right Ventricular Dysfunction, Pulmonary Hypertension
- Trial name
- CARDYCOVID (NCT04524234)
- Testing
- Echocardiography
- Where
- 5 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Sahlgrenska University Hospital
Congestive Heart Failure, Anemia
Impact of Darbepoetin Alfa on Exercise Tolerance and Left Ventricular Structure in Subjects With Symptomatic Congestive Heart Failure (CHF) and Anemia
The purpose of this study was to evaluate the effect of treatment with darbepoetin alfa on peak oxygen consumption (peak VO2) in subjects with symptomatic CHF and anemia.
- Trial name
- NCT00117234
- Testing
- darbepoetin alfa
- Sponsor
- Amgen
Left Ventricular Function Systolic Dysfunction, Cardiotoxicity
Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity
Trastuzumab prolongs survival in patients with human epidermal growth factor receptor type 2-positive breast cancer. Sequential left ventricular (LV) ejection fraction (EF) assessment has been mandated to detect myocardial…
- Trial name
- NCT01665300
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Seoul National University Hospital
Acute Myocardial Infarction, Ventricular Remodeling
Thrombectomy and Improvement of Left Ventricular Function in AMI
To study the effect of a simple and fast 'modus operandi' by aspiration of thrombus and debris with the Export catheter in an acute occlusion, on microvascular (re)perfusion and late left ventricular remodeling.
- Trial name
- NCT00288665
- Testing
- Export catheter (Medtronic)
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- R&D Cardiologie
Colon Neoplasm
Application of Overlap Method to Digestive Tract Reconstruction of Totally Laparoscopic Left Colectomy
Objective:The comparison between total laparoscopic colectomy with intracorporeal anastomosis by overlap method and laparoscopic-assisted colectomy with extracorporeal anastomosis for colon cancer surgery.
- Trial name
- NCT05034692
- Testing
- Total laparoscopic with intracorporeal anastomosis by overlap method, Laparoscopic-assisted colectomy with extracorporeal anastomosis
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Atrial Fibrillation, Stroke
Peri-device Leakage Closure After LAAO
The investigators thought to evaluate the safety and feasibility of peri-device leakage closure after left atrial appendage occlusion (LAAO, either surgical or interventional) with different devices.
- Conditions
- Atrial Fibrillation, Stroke, Bleeding, Leakage of Cardiac Device
- Trial name
- NCT04590898
- Testing
- Peri-device leakage closure after left atrial appendage occlusion
- Where
- 16 sites in United States, Denmark and 5 more
- Volunteers
- 85 people
- Sponsor
- Cardiovascular Center Frankfurt
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Efficacy and Safety of an LVEF-Guided Mavacamten Dose Up-Titration Strategy in Chinese Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy
This study aims to evaluate whether, under a treatment strategy primarily guided by left ventricular ejection fraction (LVEF), dose up-titration in adult patients with symptomatic obstructive hypertrophic cardiomyopathy who have…
- Trial name
- NCT07807384
- Testing
- Mavacamten
- Volunteers
- 115 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Cardiomyopathies
Myocardial Involvement of Severe Acute Respiratory Syndrome-Cov-2 (Covid19) Infected Patients
The effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown.
- Trial name
- COCARDE (NCT04358952)
- Testing
- Global Longitudinal Strain
- Where
- France
- Volunteers
- 122 people
- Sponsor
- University Hospital, Toulouse
ST-segment Elevation Myocardial Infarction, Left Ventricular Remodeling
The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER)
Introduction: In the setting of acute ST-segment elevation myocardial infarction (STEMI) coronary wedge pressure (CWP) emerges as a new marker for the advanced form of pre-procedural microvascular obstruction (MVO), which is…
- Trial name
- RECONSIDER (NCT03371784)
- Testing
- Hydrocortisone
- Where
- Romania
- Volunteers
- 77 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Colorectal Cancer Stage IV
Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer
The investigators hypothesize that intermittent first-line Panitumumab plus FOLFIRI is effective in first line as the same regimen given continuously, resulting in a Time to Treatment Failure (TTF) not inferior to that obtained…
- Trial name
- IMPROVE-2 (NCT06509126)
- Testing
- Panitumumab, Irinotecan, 5-fluorouracil
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- National Cancer Institute, Naples
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