Clinical trials: Left Ventricular Cardiac Dysfunction
Heart Failure
Effect of Furosemide Withdraw in Stable Chronic Heart Failure Outpatients
The ReBIC-1 trial was designed to evaluate the potential clinical risks and benefits of withdrawing furosemide use in stable, apparently euvolemic, chronic HF outpatients in a multicentric double-blinded randomized clinical trial.
- Trial name
- ReBIC-1 (NCT02689180)
- Testing
- Furosemide
- Where
- Brazil
- Volunteers
- 230 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Anterior Acute Myocardial Infarction, Left Ventricular Systolic Dysfunction
STem cElls Mobilization in Acute Myocardial Infarction Outcome Trial
The purpose of this study is to demonstrate that granulocyte colony-stimulating factor (G-CSF) therapy in addition to state-of-the-art treatment (pharmacological and non pharmacological) is safe and significantly improves…
- Trial name
- STEM-AMI (NCT01969890)
- Testing
- G-CSF administration
- Where
- 53 sites in Italy
- Volunteers
- 532 people
- Sponsor
- Heart Care Foundation
STEMI, Oxidative Stress
Correlations Between Oxidative Stress Biomarkers, h-FABP and Left Ventricular Dysfunction in Patients With Acute Myocardial Infarction Undergoing Primary PCI
The investigators intend to evaluate Oxidative Stress biomarkers through a. Catalase Activity Assay; b. Lipid Peroxidation Assay; c. SOD Assay; d. Total Antioxidant Capacity Assay; e.
- Conditions
- STEMI, Oxidative Stress, Oxidative Stress Induction, Primary PCI
- Trial name
- OxiSTEMIhFABP (NCT04034940)
- Testing
- Dosing Oxidative stress biomarkers & hFABP in STEMI pPCI patients
- Where
- Romania
- Volunteers
- 200 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Peripartum Cardiomyopathy, Diastolic Dysfunction
Diastolic Dysfunction PPCM in Patients With Documented Left Ventricular Systolic Function Recovery
The purpose of this project is to evaluate parameters of diastolic dysfunction assessed by clinical echocardiogram in patients who have had recovery of systolic function.
- Trial name
- NCT04143997
- Testing
- A clinical Transthoracic echocardiogram
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Stroke, Epilepsy
Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases
Neurological and cardiovascular diseases are increasing in relative and absolute terms globally, and pose a major burden in terms of morbidity, mortality, quality of life and healthcare costs.
- Conditions
- Stroke, Epilepsy, Transient Global Amnesia (TGA)
- Trial name
- G-HeBra (NCT07009990)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald