Clinical trials: Leg Edema
Lymphedema, Chronic Venous Insufficiency
A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)
To demonstrate that the Insight Pro Device is safe and effective for use in detecting lymphatic and venous disorders.
- Conditions
- Lymphedema, Chronic Venous Insufficiency, Edema, Venous Insufficiency of Leg
- Trial name
- VOLGA (NCT05628688)
- Testing
- Insight Pro Device for Diagnosis
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Koya Medical, Inc.
Edema Leg
Cross Therapy Registry - Oedema - EU (CTR-Oedema-EU)
The geko™ Cross Therapy Registry - Oedema - EU (gekoTM CTR - Oedema- EU) study will prospectively and systematically collect clinical data on all device variants used in standard care pathways for edema management allowing for…
- Trial name
- CTR-Oedema-EU (NCT04704557)
- Testing
- geko Neuromuscular Electro Stimulator (NMES)
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- Firstkind Ltd
Lipedema
Effects of Exercise in Patients with Lipedema
Lipedema is a chronic progressive disease characterized by symmetrical, disproportionate swelling of subcutaneous adipose tissue, which is common in women and mostly seen in the lower extremities and to a lesser extent in the…
- Trial name
- NCT06811961
- Testing
- Exercise, Physical activity
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ilke Keser
Pain, Leg Edema
is Ultrasound-guided Foam Sclerotherapy a Cost-effective Alternate for Treatment of Varicose Veins?
. It is the aim of this paper is to discuss our experience of foam sclerotherapy for varicose veins atour hospital
- Conditions
- Pain, Leg Edema, Cost Effectiveness, Cosmesis
- Trial name
- NCT04655417
- Testing
- Sodium Tetradecyl Sulfate
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital, Pakistan
Heart Failure; With Decompensation, Lower Extremity Edema
Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.
Heart failure (HF) remains one of the most common causes of hospitalization with high morbidity and mortality, and its worldwide prevalence is increasing.
- Conditions
- Heart Failure; With Decompensation, Lower Extremity Edema, Heart Failure，Congestive
- Trial name
- A-KHALIFE (NCT05467735)
- Testing
- Application of compression to bilateral lower extremities of patients using appropriately-sized elastic compression stockings.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Medical Branch, Galveston
ADHF
3-dimensional Sensor Technology to Quantify Leg-edema
The purpose of the study is two-fold: 1. to test 3-dimensional reconstruction of leg-edema in patients hospitalized for acute heart failure with leg-edema. 2.
- Trial name
- NCT01700023
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Medical University of Graz
Leg Injuries, Fracture
Soft Part Management for Surgical Fractures of the Lower Limb
The assessment consists in comparing corticoids injection versus placebo in surgery of lower limb fractures The aim of study is to assess (state cutaneous, efficacy, safety) corticoids injection on a prospective, randomized…
- Conditions
- Leg Injuries, Fracture, Edema
- Trial name
- ICOMI (NCT03915223)
- Testing
- leg fracture
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Clermont-Ferrand
Post Thrombotic Syndrome
Treatment Trial for Post-Thrombotic Syndrome
The purpose of this study is to determine if complex lymphedema therapy is effective in decreasing disease severity and improving quality of life in patients with post thrombotic syndrome.
- Trial name
- NCT00633971
- Testing
- complex lymphedema therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Vermont
Nocturia, Venous Insufficiency of Leg
Discovering the Effect of Venous Insufficiency on Nocturia
With this prospective controlled trial, we hope to obtain more information about the coexistence between venous insufficiency and nocturia.
- Conditions
- Nocturia, Venous Insufficiency of Leg, Fluid Overload
- Trial name
- DEVINe (NCT04266496)
- Testing
- Questionnaires, Frequency Volume Chart, Collect urine during 1 day
- Where
- Belgium
- Volunteers
- 84 people
- Sponsor
- University Hospital, Ghent
Ankle Injuries, Fracture
Lymphomyosot for Ankle Edema Following Fracture
Ankle fractures are invariably complicated by severe soft-tissue swelling which can significantly prevent surgical repair (open reduction and internal fixation - ORIF) of the fractured bone for up to two weeks.
- Trial name
- NCT00884988
- Testing
- Lymphomyosot
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Shaare Zedek Medical Center
Chronic Edema, Lymphedema
Boosted Compression for Lower Limb Chronic Edema
Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care…
- Trial name
- BECOME (NCT07708662)
- Testing
- Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy
- Where
- 4 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Universiteit Antwerpen
Kidney Transplant, Kidney Pancreas Transplant
The Effect of Neuromuscular Stimulation on Post-Transplant Leg Edema
This will be a randomized, controlled trial involving kidney and kidney pancreas transplant patients. There will be 2 groups and patients that will be randomized to one of the two groups.
- Conditions
- Kidney Transplant, Kidney Pancreas Transplant, Edema
- Trial name
- NCT01860820
- Testing
- Geko device
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lower Extremity Swelling, Lower Extremity Edema
Game-Based Foot & Ankle Exercise for Those With Lower Extremity Edema
The present study aims to use a game-based tele-exercise program for patients using a compression garment to improve lower extremity edema.
- Conditions
- Lower Extremity Swelling, Lower Extremity Edema, Venous Insufficiency of Leg
- Trial name
- NCT05520008
- Testing
- Game-based exercise
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor College of Medicine
Pregnancy Complication
Title of the Research: Effect of Manual Lymphatic Drainage Massage Combined With Therapeutic Exercises On Lower Limbs Edema During Late Pregnancy
Objective of the study is to investigate the effect of adding manual lymphatic drainage massage to classical therapeutic exercises on resolving physiological lower limbs edema in late pregnancy women.
- Trial name
- NCT07761741
- Testing
- manual lymphatic drainage massage technique with specific therapeutic exercise
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Pregnancy Related
Effects of Foot Exercises and Hydrotherapy on Pedal Edema & Lower Extremity Function
To determine the Effects of foot exercises with and without hydrotherapy on pedal Edema \& lower extremity function in antenatal women.
- Trial name
- NCT05777538
- Testing
- hydrotherapy, foot exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Edema Leg
Cross Therapy Registry - Edema - US
The geko™ Cross Therapy Registry - Edema (gekoTM CTR - Edema) study will prospectively and systematically collect clinical data on all device variants used in standard care pathways for edema management allowing for the…
- Trial name
- CTR-Edema-US (NCT04700735)
- Testing
- geko Neuromuscular Electro Stimulator (NMES)
- Where
- 3 sites in United States
- Volunteers
- 83 people
- Sponsor
- Firstkind Ltd
Right Heart Failure, Cor Pulmonale
Effect of Normatec Pump for Relief of Leg Edema in Patients With Right Heart Failure
Mobilization of fluid from the legs with the Normatec pump in patients with right heart failure, may empty the "reservoir" in the legs from excessive fluid, enabling fluid overload to collect there rather than in the liver or in…
- Trial name
- NCT00834145
- Testing
- A mechanical compression pump
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Lower Extremity Edema, Lower Extremity Edema Chronic
Pedal Pump Clinical Trial on Edema V2
Previous research on the osteopathic manual technique entitled "Pedal Pump" has shown health benefits, specifically increasing lymphatic flow, decreasing lower extremity edema, and decreasing serum lactic acid after maximal…
- Conditions
- Lower Extremity Edema, Lower Extremity Edema Chronic, CHF - Congestive Heart Failure, CHF Exacerbation
- Trial name
- NCT07809516
- Testing
- Pedal Pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hillcrest
Fluid Overload
Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs
Impact of intraoperative use of pneumatic peristaltic compression device on hemodynamics vis a vis on fluid requirement during general anaesthesia and surgery.
- Trial name
- NCT03789474
- Testing
- HUNTLEIGH FLOWTRON ACS900
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Leg Edema, Venous; Return (Anomaly)
Elevate to Alleviate Evidence Based Study
Venous return in the circulatory system of lower limbs results from the interaction of several mechanisms, and reflects the balance between blood inflow and outflow.
- Conditions
- Leg Edema, Venous; Return (Anomaly), Leg Elevation
- Trial name
- ETA (NCT04514939)
- Testing
- Elevation of the legs during bed rest
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Catanzaro