Clinical trials: Leg Injuries
Femur Fracture
Evaluation of the Postoperative Analgesic Efficacy of the Quadroiliac Plane (QIP) Block in Femur Fracture Surgery
The goal of this clinical trial is to learn whether the Quadroiliac Plane (QIP) block helps reduce postoperative opioid use in adults undergoing femur fracture surgery.
- Trial name
- NCT07009782
- Testing
- QIP block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
ACL Injury
Continuous Vs Single Shot Block After ACL
The investigators will be randomizing patients to either receive an adductor canal block in the operating room postoperatively as single shot of 20-30cc bupivacaine or to have a catheter inserted into the adductor canal which…
- Trial name
- NCT04101682
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Delirium, Hip Fracture
Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.
Post operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and increased mortality.
- Trial name
- RASAPOD (NCT02689388)
- Testing
- Femoral Nerve Block
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Auckland City Hospital
Complications; Arthroplasty, Knee Injuries
Ultrasound-guided Adductor Canal Block for Total Knee Replacement
Total knee arthroplasty is associated with intense early postoperative pain. Fast track recovery programs including early therapy protocols and early hospital discharge are being implemented at various hospitals.
- Trial name
- NCT02100579
- Testing
- Bupivacaine, Preservative free normal saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Fractured Neck of Femur
Single Dose of Dexamethasone in Femur Fractures
Fracture neck of femur is a common cause of hospital admission in the elderly and requires operative fixation. Dexamethasone has the potential of inhibiting cortisol secretion.
- Trial name
- NCT01550146
- Testing
- Dexamethasone acetate
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
Hip Fractures, Hemodynamic Stability
Hemodynamic Safety of Levobupivacaine vs Bupivacaine in Patients Over 65 Years Undergoing Hip Surgery
The altered hemodynamics, and therefore the arterial hypotension is the most prevalent adverse effect after subarachnoid anesthesia.
- Trial name
- NCT03843970
- Testing
- Levobupivacaine Hydrochloride 0.5%, Isobaric bupivacaine 0.5%
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Clínico Universitario de Valencia
Pelvic Fracture
Pelvic Fractures in the Elderly
The aim of the project is to predict the patient under conservative therapy as a function of the patient Classification of Rommens and Hofmann and other potential prognostic factors.
- Trial name
- PelvFx (NCT03476824)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Spinal Cord Injury
Lokomat Versus Strength Training in Chronic Incomplete Spinal Cord Injury
The purpose of this pilot study is to investigate whether gait specific robotic supported bodyweight supported treadmill training and lower extremity strength training have similar beneficial effects on walking function and other…
- Trial name
- NCT01087918
- Testing
- RAGT, Strength Training
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
ACL Injury, Knee Injuries
Subjective Outcomes After ACL Reconstruction With BQT Autograft
The purpose of the study is to compare short-term patient reported outcome measures (PROM) of Bone-Quadriceps-Tendon (BQT) autograft with Semitendinosus-Gracilis (STG) and Bone-Patellar-Tendon-Bone (BPTB) autografts following…
- Trial name
- NCT04901559
- Testing
- Graft type at ACLR
- Volunteers
- 30,000 people
- Sponsor
- Region Zealand
Hip Fracture, Blood Loss
Can Thrombelastography Predict Blood Loss in Patients With Hip Fractures
Hip fractures are associated with a large hidden blood loss. That is, the total blood loss associated with hip fracture surgery is much greater than that observed intra operatively.
- Trial name
- NCT02297061
- Testing
- Thrombelastography analysis (TEG)
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Hvidovre University Hospital
ACL Injury
Immediate Versus Optional Delayed Surgical Repair for Treatment of Acute ACL Injuries
Currently, most patients with an anterior cruciate ligament injury undergo surgery. There is a general belief that surgical reconstruction is necessary to safely return to sports and to prevent early knee osteoarthritis or…
- Trial name
- IODA (NCT05747079)
- Testing
- Rehabilitation, Optional delayed anterior cruciate ligament reconstruction, Immediate anterior cruciate ligament reconstruction
- Where
- Belgium
- Volunteers
- 280 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Critically Ill Patients, Neutropenic Fever Patients
Observational Prospective Study of the Predicted Value of Immature Thrombocytes Counts in Three Different Groups of Critically Ill Patients
Immature Platelet Fraction (IPF) is a new value in CBC blood tests Recent Studies showed that this value may be another prognostic factor in critically ill patients such as those admitted to ICU, or those with neutropenic Fever.
- Conditions
- Critically Ill Patients, Neutropenic Fever Patients, Patients With Hip Fractures
- Trial name
- NCT02016859
- Testing
- Immature Platelet Fraction
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Dr. Yishai Ofran
Knee Pain Chronic, Knee Injuries
Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%
Non-steroidal anti-inflammatory medication (NSAID) therapy is a mainstay treatment for joint pain and painful musculoskeletal disorders.
- Trial name
- NCT02068859
- Testing
- Diclofenac Cream 8%, Diclofenac Gel 1%
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- FPR Specialty Pharmacy
Ventricular Dysfunction, Left, Hip Fracture
Preoperative levosimendán and Hip Fracture
The purpose of this study is to evaluate whether preoperative optimization with levosimendan in heart failure patients undergoing hip fracture surgery improves haemodynamic and tissue perfusion parameters.
- Trial name
- OPL (NCT02972918)
- Testing
- Levosimendan
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Hospital Universitario de Canarias
Ankle Fractures, Splints
Post Operative Ankle Splint Study - Prospective Multi Center Randomized Controlled Trial
Background: Ankle fractures are some of the most common orthopedic presentations, however, controversy in their management and their post-operative rehabilitation protocols exist.
- Trial name
- PASS (NCT04796168)
- Testing
- Splinting (plaster of paris)
- Where
- Kuwait
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuwait Institute for Medical Specialization
Diabetic Foot Ulcer
A Prospective Trial of Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AC
This trial is a multicenter, randomized, controlled study designed to evaluate the safety and efficacy of BioREtain® Amnion Chorion (BR-AC) plus standard of care versus standard of care only in the treatment of diabetic foot…
- Trial name
- NCT06511596
- Testing
- BR-AC, Standard Care
- Where
- 11 sites in United States
- Volunteers
- 71 people
- Sponsor
- BioStem Technologies
Femoral Neck Fracture
Ropivacaine Hypobaric Spinal Anaesthesia in Traumatic Hip Surgery
This is a prospective, monocentric, randomized study, comparing the effectiveness and tolerance of four different dosages of hypobaric ropivacaine for unilateral spinal anaesthesia during traumatic femoral neck surgery in the…
- Trial name
- NCT01005550
- Testing
- 6 mg of ropivacaine, 8 mg of ropivacaine, 10 mg of ropivacaine
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Proximal Femur Fractures
Development and Validation of Intraoperative Image-quality Criteria
An expert panel of surgeons agreed that there is not any established, standardized approach to the teaching of intraoperative imaging and that there may be practice gaps in decision making and the use of imaging among trauma…
- Trial name
- NCT01660490
- Testing
- ORIF
- Where
- 3 sites in United States, Austria and 1 more
- Volunteers
- 200 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Diabetic Foot Ulcer
Restoring Tissue and Evaluating Novel Treatments for Efficacy in Wounds
This is an IRB-approved multicenter study.This non-inferiority study aims to evaluate differential healing rates between Lavior Diabetic Wound Gel and other Hydrogels.
- Trial name
- RENEW (NCT05607979)
- Testing
- Lavior Diabetic Wound Gel, Smith & Nephew Solosite Gel Hydrogel Wound Dressing
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lavior Pharma Inc.
Ankle Fracture
Bedside Ultrasound in the Diagnosis of Ankle Fractures in Children
Objectives: A lot of children who injure their ankles come to the emergency department for an evaluation, and often an X-ray of the ankle is obtained to determine if a bone fracture is present.
- Trial name
- NCT01341015
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rhode Island Hospital