Clinical trials: Leg Injuries and Disorders
Hip Fractures
Early Femoral Block in Elderly With Hip Fracture
Assess if the addition of an early femoral nerve block (performed within 2 hours from the admission in emergency department through a femoral nerve catheter) in the elderly patients (> 70 years) with hip fracture, reduces the…
- Trial name
- NCT03092466
- Testing
- femoral nerve catheter, femoral group, control group
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- ASST Gaetano Pini-CTO
Chronic Skin Ulcer, Diabetic Foot Ulcer
Comparison of Platelet-Rich Plasma Dressing Versus Normal Saline Dressing for Chronic Non-Healing Ulcers
This randomized controlled trial will compare platelet rich plasma dressing with normal saline dressing for the treatment of chronic non healing cutaneous ulcers, including diabetic foot ulcers, venous leg ulcers, pressure…
- Trial name
- NCT07420868
- Testing
- Platelet Rich Plasma Dressing, Normal Saline Dressing
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Multan Medical And Dental College
Ankle Sprain
Topical Ketoprofen Versus Placebo in Patients With Ankle Sprain
The aim of this study is to analyse the effect of ketoprofen gel in patients presented with ankle sprain to the emergency department.
- Trial name
- NCT02393846
- Testing
- Ketoprofen gel
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University
Ankle Injuries, Foot Injury
How is Calf Muscle Endurance Related to Ankle Injuries in TeamGym Athletes?
The specific aims of this study are to: describe how many heel raises and side hops TG athletes of various ages can perform and how far they can jump, one leg at a time.
- Conditions
- Ankle Injuries, Foot Injury, Overuse Injury, Ankle Sprains
- Trial name
- NCT05323773
- Where
- Sweden
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Susanne Beischer
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Can we 'Hear' Femoral Neck Fractures? Ultrasound Guided Diagnosis of Femoral Neck Fractures
Hip (femoral neck and pertrochanteric) fractures account for a significant part of Emergency Department (ED) visits after trauma.
- Trial name
- CHEFF (NCT06765083)
- Testing
- POCUS of the hip
- Where
- Netherlands
- Volunteers
- 146 people
- Sponsor
- Frisius Medisch Centrum
Knee Dislocation
Knee Dislocation - Clinical Evaluation of the Use of Hinged External Fixator After Ligament Reconstruction
Knee dislocation is a serious injury, usually caused by high-energy trauma. It is classically defined as complete loss of articular congruence between the femur and the tibia, confirmed by radiography.
- Trial name
- NCT02290197
- Testing
- Surgery, Hinged External Fixator, Cast Immobilization
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Sensory Disorder, Sensory Processing Disorder
Investigation of Sensory Processing Patterns of Elderly Individuals Who Have Had Hip Fracture Surgery
This study aims to evaluate the sensory processing processes of elderly adults who have undergone fall-related hip fracture surgery in the last 6 months, according to different patterns, and to examine the relationship between…
- Conditions
- Sensory Disorder, Sensory Processing Disorder, Hip Fractures, Fall Injury
- Trial name
- NCT05811559
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Atlas University
Aging, Muscle Weakness
Leg Heat Therapy in Elderly Individuals
This pilot randomized, sham-controlled trial aimed to establish the feasibility and safety of home-based leg HT in community-dwelling older adults and inform the design of a future, larger study.
- Trial name
- NCT05543980
- Testing
- Leg heat therapy device
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Diabetic Foot
The Association Between Unprotected Standing, Walking and Wound Healing in Diabetes
The aim of the study was to explore the association between activities of daily living ( measured using a body-worn sensor) on wound healing in diabetic patients. Since this was an exploratory study, there was no study hypothesis.
- Trial name
- NCT02233179
- Testing
- Removable cast walker, Irremovable cast walker
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Arizona
Diabetic Foot Ulcer, Diabetic Foot
Exercise Therapy for People With a Diabetic Foot Ulcer - a Feasibility Study
The aim of this feasibility study is to evaluate a 12-week exercise intervention in people with an active diabetic foot ulcer through pre-defined research progression criteria (participant recruitment and retention, duration of…
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Wound Healing Disorder, Ulcer Foot
- Trial name
- NCT05101473
- Testing
- Exercise Therapy
- Where
- Denmark
- Volunteers
- 3 people
- Sponsor
- Holbaek Sygehus
Diabetic Foot, Sleep Apnea
Impact of Sleep Apnea on Diabetic Foot Wound.
Sleep apnea syndrome (SAS) is a common comorbidity of type 1 and type 2 diabetes. A low transcutaneous oxygen tension (PtcO2) measured on the foot is pejorative prognostic factor for the healing of a diabetic foot wound.
- Trial name
- SAS-FOOT (NCT01573897)
- Where
- France
- Volunteers
- 35 people
- Sponsor
- AGIR à Dom
Foot Ulcer, Diabetic
Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix
The objective of this study is to compare the effectiveness of PriMatrix Moist Wound Therapy (MWT) with Standard of Care MWT for the treatment of chronic diabetic foot ulcers in subjects with diabetes mellitus and without…
- Trial name
- HEALED (NCT01729286)
- Testing
- PriMatrix Moist Wound Therapy, Standard of Care Moist Wound Therapy
- Where
- 18 sites in United States, Puerto Rico
- Volunteers
- 92 people
- Sponsor
- Integra LifeSciences Corporation
Diabetic Foot, Foot Ulcer
ENERGI-F703 for Diabetic Foot Ulcers Phase II Study
The objective of this study is to evaluate the efficacy and safety of ENERGI-F703 in subject with diabetic foot ulcers.
- Conditions
- Diabetic Foot, Foot Ulcer, Diabetes Mellitus, Wounds
- Trial name
- NCT02672436
- Testing
- ENERGI-F703, ENERGI-F703 matched vehicle
- Where
- Taiwan
- Volunteers
- 141 people
- Sponsor
- Energenesis Biomedical Co., Ltd.
Hip Injuries, Fractures, Hip
Mitigation of Major Hip Injury Due to Fall With a Smart Belt
Multi-center, comparative, non-significant risk adaptive study with retrospective controls. After providing informed consent and being screened for eligibility, intervention subjects will be prescribed and provided an…
- Conditions
- Hip Injuries, Fractures, Hip, Fall Injury, Fall Risk
- Trial name
- NCT05245097
- Testing
- Tango Belt, Standard of Care (SOC)
- Where
- 10 sites in United States
- Volunteers
- 471 people
- Sponsor
- ActiveProtective Technologies, Inc
Anxiety, Pain
Effects of Music on Preoperative Anxiety in Patients With Femoral Fractures Undergoing Surgery
This randomized controlled trial (RCT) investigates the effectiveness of music therapy in reducing preoperative anxiety among elderly patients with femoral fractures.
- Conditions
- Anxiety, Pain, Surgery, Femoral Fractures
- Trial name
- NCT07008482
- Testing
- Music intervention
- Volunteers
- 154 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Diabetic Foot Ulcer
Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation
The purpose of this interventional study is to assess the effectiveness of CARE-D-Foot, a patient navigator intervention, as compared to usual care, on 20-week diabetic foot ulcer healing.
- Trial name
- NCT07223268
- Testing
- CARE-D-Foot-Nav, Standard of care
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Emory University
Stroke, Hip Fractures
the Efficacy of Core Stability Training in Rehabilitation
The goal of the study is to verify the efficacy of core stability training in rehabilitation of patients after hip fracture and in patients after stroke.
- Trial name
- Omino (NCT07010848)
- Testing
- Core stability training
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Osteoporosis
Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients
The objective of this study is to determine if an intervention with a fracture manager to arrange bone densitometry after a hip fracture is more effective in diagnosing and treating osteoporosis when compared to "usual care".
- Trial name
- NCT00136058
- Testing
- bone densitometry (DEXA), alendronate or risedronate
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University of Alberta
Wound Heal, Diabetic Foot Ulcer
EDX110 Randomized Control Trial for Treatment of DFUs
Prospective, multi-centered, observer blinded, pre-market study, 1:1 randomized control trial, to determine if addition of EDX110 dressing system to standard of care leads to an improvement in diabetic foot ulcers healing…
- Trial name
- NCT07209358
- Testing
- EDX110
- Where
- 10 sites in United States, Puerto Rico
- Volunteers
- 300 people
- Sponsor
- ConvaTec Inc.
Chronic Wounds, Biofilm Infection
Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence
This work is based on DFU patients, seeks to conduct a fully powered clinical study testing i) If DFU with a history of biofilm infection closes with deficient barrier function.
- Conditions
- Chronic Wounds, Biofilm Infection, Trans-epidermal Water Loss (TEWL), Diabetic Foot
- Trial name
- DFUBiofilm (NCT05172089)
- Where
- 2 sites in United States
- Volunteers
- 405 people
- Sponsor
- University of Pittsburgh
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