Clinical trials: Leg Injuries and Disorders
Vascular Disease, Peripheral, Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Correlating Multispectral Near-Infrared Imaging to Standard Vascular Diagnostics
The goal of this observational study is to learn if the measures of tissue oxygenation from the MIMOSA Pro imaging device correlate to standard vascular assessment tools in patients who receiving a lower extremity vascular…
- Trial name
- NCT06899113
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MIMOSA Diagnostics Inc.
Hip Fractures, Anesthesia
Fractional Spinal Anesthesia and Systemic Hemodynamics in Frail Elderly Hip Fracture Patients.
Aging and frailty make the elderly patients susceptible to hypotension following spinal anaesthesia. The systemic haemodynamic effects of spinal anaesthesia are not well known.
- Conditions
- Hip Fractures, Anesthesia, Hypotension Drug-Induced, Cardiac Output, Low
- Trial name
- NCT05101291
- Testing
- Bupivacain
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Sahlgrenska University Hospital
Wounds, Diabetes Complications
Online Wound Electronic Medical Record (OWEMR) to Decrease Amputations in Diabetics
The purpose of this study is to determine whether using the OWEMR as part of the standard of care for Diabetic Foot Ulcers reduces the rate of lower limb amputations and to quantify the relationship between glycemic control and…
- Conditions
- Wounds, Diabetes Complications, Diabetic Foot, Foot Ulcer
- Trial name
- OWEMR (NCT01371318)
- Testing
- Online Wound Electronic Medical Record
- Where
- 13 sites in United States
- Volunteers
- 1,609 people
- Sponsor
- NYU Langone Health
Ligament; Laxity, Recurrent Patellar Dislocation
Clinical Significance and Coexistence of Polymorphisms of Individual Collagen-coding Genes
The purpose of this study is to assess correlation between recurrent patella dislocation and genetic polymorphism rs1800012 of the COL1A1 Gene and rs12722 of the COL5A1 Gene.
- Trial name
- NCT05763108
- Testing
- genetic test, Beighton joint laxity test
- Where
- 2 sites in Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Chronic Ulcer of Leg or Foot, Pressure Injury
A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Safety, and Performance of ConvaFoam™ Dressings in the Management of Indicated Chronic Wound Types.
A prospective, multi centre, interventional, non-comparator, open label study to demonstrate the efficacy, safety, and performance of ConvaFoam™ dressings in the management of indicated chronic wound types.
- Trial name
- MORGEN (NCT05632250)
- Testing
- ConvaFoam
- Where
- 5 sites in United States
- Volunteers
- 95 people
- Sponsor
- ConvaTec Inc.
Total Hip Replacement
Efficiency of the Adjustable Lower Extremity Abduction Apparatus After Total Hip Replacement Surgery
This study was conducted to evaluate the effect of the adjustable lower extremity abduction apparatus developed after total hip arthroplasty (TKP) surgeries on preventing dislocation and walking.The study is of randomized…
- Trial name
- NCT06169878
- Testing
- Adjustable lower limb abduction apparatus
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bahçeşehir University
Diabetes, Foot Wound
Comparing the Efficacy of the ConvaTec Engenex® Negative Pressure Wound Therapy Device to Moist Wound Therapy
This is an investigator-initiated prospective, randomized, controlled study. Hypothesis/Objective: The study will evaluate the rates of wound healing among patients with lower extremity diabetic wounds comparing two groups of…
- Trial name
- NCT01108276
- Testing
- Convatec engenex negative pressure wound therapy
- Sponsor
- Georgetown University
ACL Injury
Multimodal Assessment of Knee Conditions in Rehabilitation
The purpose of this study is to assess ACL injury and other pathological knee conditions from the combination of signals that are known to provide information on the knee joint.
- Trial name
- NCT03608189
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Oulu
Diabetic Polyneuropathy, Foot Injuries
Spatio-Temporal Gait Parameters and Gait Symmetry In Diabetic Lower Extremity Burn Injury.
This study evaluated the spatio-temporal gait parameters and gait symmetry in individuals with lower extremity burn injury due to diabetic polyneuropathy.
- Trial name
- NCT03687840
- Testing
- gait analysis
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Blood Lactic Acid Increased, Hip Fractures
Optimal Blood Sampling Site for Point of Care Lactate Assessment
The study was to compare blood Lactate levels between ear lobe and finger against venous forearm blood sample using the electronic hand held lactate device in hip fracture patients with good cognitive function (AMT >/= 7)
- Trial name
- NCT04291989
- Testing
- Optimal Blood Sampling Site for Point of Care Lactate Assessment using the handled Lactate-Pro 2 device
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Degenerative Osteoarthritis, Rheumatic Arthritis
CoreHip - Post Market Clinical Follow-Up Study
The study is designed as a prospective, non-interventional multicentre cohort study. The product under Investigation will be used in Routine clinical practice and according to the authorized Instructions for Use (IfU).
- Conditions
- Degenerative Osteoarthritis, Rheumatic Arthritis, Fractures, Hip, Necrosis, Femur Head
- Trial name
- NCT03685110
- Testing
- CoreHip Total Hip Arthroplasty
- Where
- 6 sites in Germany, Switzerland
- Volunteers
- 248 people
- Sponsor
- Aesculap AG
Foot Ulcer, Diabetic
Assessing the Effects of ELO Water on Diabetic Foot Ulcers
This pilot study examined the effects of ELO water, a commercially-available oxygen-enriched drinking water, on wound healing in patients with diabetic foot ulcers over 12 weeks.
- Trial name
- NCT05908968
- Testing
- ELO water
- Where
- Singapore
- Volunteers
- 16 people
- Sponsor
- Changi General Hospital
Hip Fractures
Vibration Therapy as an Intervention for Enhancing Trochanteric Hip Fracture Healing in Elderly Patients
Currently, there are approximately 300,000 hip fractures per year in the US with a mortality rate of 20% within 1 year. In Hong Kong, around 6,000 hip fractures occur yearly with costs approximately 52 million USD, and these…
- Trial name
- NCT04063891
- Testing
- Low-magnitude high-frequency vibration (LMHFV)
- Where
- Hong Kong
- Volunteers
- 83 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Diabetic Foot Ulcer, Venous Leg Ulcer
Cold atmOspheric plaSMa Therapy Versus standArd Wound Care in Diabetic Foot and Venous Leg ulcerS
Chronic wounds such as diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs) pose a major health burden to the patients but also to the healthcare system because of their distorted healing capacity.
- Trial name
- COSMAS (NCT07251426)
- Testing
- COLD ATMOSPHERIC PLASMA
- Volunteers
- 494 people
- Sponsor
- Olaf Bakker
Stress Fracture, Ultrasound Therapy
Comparison of Ultrasound and X-ray as Screening Tests for Diagnosis of Lower Extremity Stress Fracture.
Hypothesis: Diagnostic ultrasound is an appropriate screening test for acute stress fracture in the lower extremity and is superior to x-ray.
- Conditions
- Stress Fracture, Ultrasound Therapy, Musculoskeletal Ultrasound
- Trial name
- NCT03116360
- Testing
- Diagnostic Ultrasound
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Meniscus Tear, Tibial, Osteoarthritis, Knee
Arthroscopic Partial Meniscectomy Versus Exercise Therapy for Meniscal Injuries in Older Patients, a 5 Year Follow up.
Arthroscopic partial meniscectomie (APM) offers little short-term to medium-term benefit above sham surgery or non-surgical management for knee function in most patients with a symptomatic degenerative meniscus tear.
- Trial name
- NCT05068843
- Testing
- arthroscopic partial meniscectomy, Physical therapy
- Volunteers
- 321 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Injection Pressure & Adductor Canal Block
This is a prospective, randomized, single-blinded human clinical trial that will examine how injection pressure influences the spread of a given volume of injectate in the adductor canal, during adductor canal nerve block.
- Trial name
- NCT02563990
- Testing
- High Pressure Injection, Low Pressure Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
Motor Disorders, Gait Disorders, Neurologic
Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population
In 2019, approximately 2.4 billion people worldwide required rehabilitation for various health pathologies, a 63% increase since 1990.
- Conditions
- Motor Disorders, Gait Disorders, Neurologic, Neurodegenerative Diseases, Spinal Cord Injuries
- Trial name
- ALERT (NCT06538974)
- Testing
- Hands-free exoskeleton
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Wandercraft
Hallux Limitus
Contracture Reduction Following Bunionectomy: a Longitudinal, Controlled Trial
To determine the efficacy of Metatarsal Dynasplint Sytem (MTP) in reducing contracture of hallux limitus secondary to Bunionectomy, in a longitudinal, controlled trial.
- Trial name
- Bunionectomy (NCT01589679)
- Testing
- standard of care, Metarsal Dynasplint
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Dynasplint Systems, Inc.
Hip Dysplasia
The Influence of Hip Replacement on Lower Extremity Hemodynamics in Crowe IV Hip Dysplasia Patient
Explore the influence of hip replacement on lower extremity hemodynamics in Crowe Ⅳ hip dysplasia patient.
- Trial name
- NCT04157842
- Testing
- total hip replacement with subtrochanteral osteotomy, total hip replacement with no osteotomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine