Clinical trials: Leg Injuries and Disorders
Gastroparesis, Hip Fracture
Gastric Emptying in Elderly With Hip Fracture
The gastric emptying of 400 ml 12.6% carbohydrate rich drink is investigated in elderly women, age 75-100, with acute hip fracture.
- Conditions
- Gastroparesis, Hip Fracture, Mild Insufficient Nutrition
- Trial name
- GASEMPHIP (NCT02753010)
- Testing
- Gastric emptying of carbohydrate-rich beverage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Diabetic Foot Ulcer
Safety and Efficacy of HO/03/03 10μg in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers
A prospective, double blind, randomized, placebo controlled, outpatient, parallel group comparison trial to assess the safety and efficacy of HO/03/03 10µg versus Placebo, applied topically once daily for up to 14 weeks in at…
- Trial name
- Truheal (NCT00926068)
- Testing
- HO/03/03 10µg
- Where
- 33 sites in United States, India
- Volunteers
- 196 people
- Sponsor
- HealOr
Spinal Cord Injuries, Rehabilitation
Effects of Walking Training on Different Surfaces on Walking Ability in Ambulatory Patients With Spinal Cord Injury
The study compares effects of 4-week walking training program on a walking track with difference surface [WTDS] and a firm ground on functional ability of ambulatory individuals with incomplete spinal cord injury [iSCI], using…
- Trial name
- NCT03622710
- Testing
- Rehabilitation therapy
- Where
- Thailand
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Venous Leg Ulcer
A Multicentre European Study to Evaluate Granulox® Used in the Treatment Pathway of Predominantly Chronic Venous Leg Ulcers (VLUs).
The investigation is designed as an open label, randomized, prospective, assessor blinded, multi centre investigation. 254 evaluable subjects will be randomized to either standard of care group or standard of care with Granulox…
- Trial name
- Granulox01 (NCT04181320)
- Testing
- Venous Leg Ulcer Standard of Care with Granulox
- Where
- 27 sites in Croatia, Czechia and 5 more
- Volunteers
- 128 people
- Sponsor
- Molnlycke Health Care AB
Knee Osteoarthritis, Knee Injuries
Evaluation of Clinical Outcomes of Scaffold Treatment of Partial Meniscal Injuries of the Knee
The study consists of 3 phases (Identification of includable patients, Telephone follow-up evaluation and the collection of study-specific clinical data in medical records of enrolled patients): Identification by trained medical…
- Conditions
- Knee Osteoarthritis, Knee Injuries, Meniscus Lesion
- Trial name
- STAR-ACT (NCT06475963)
- Testing
- surveys
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Istituto Ortopedico Rizzoli
Toddler's Fracture
Toddlers Fractures - Cast Versus Removable Boot
A toddler's fracture is a fracture that occurs in the lower leg, oven the shin, of children 9 months to four years of age. It usually happens when a young child twists the leg while running or jumping.
- Trial name
- NCT03971448
- Testing
- LPWB, AKWC
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- The Hospital for Sick Children
Muscle Injury, Lower Limb Injury
Effects of ART® on Lower Limb Myofascial Pain and Function
This is a feasibility study to determine if the investigators can conduct a clinical trial with a sham and control soft tissue treatment.
- Trial name
- NCT04535635
- Testing
- Active Release Techniques®
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Canadian Memorial Chiropractic College
Hip Fractures
Clinical Outcomes of Analgesia Methods in Patients With Hip Fracture
The goal of this study is to determine of clinical outcomes of analgesia methods. The primary outcomes are opioid consumption, static and dynamic visual analog scale (VAS) scores. Secondary outcomes are occurrence of side effects.
- Trial name
- NCT03670290
- Testing
- Fascia iliaca compartment catheter, epidural catheter, patient controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mersin University
Hip Disease, Hip Fractures
Observational Study Conducted on Patients Receiving the ESOP 2 Stem to Confirm Security and Performance of the Device
This study is a post-market clinical follow-up conducted in order to collect long-term data on security and performance of the ESOP 2 stem, which is intended to be implanted in case of total hip replacement, when used in real…
- Trial name
- ESOP2 (NCT04193163)
- Testing
- Hip prosthesis - ESOP 2 cementless femoral stem
- Where
- 7 sites in France
- Volunteers
- 10 people
- Sponsor
- FH ORTHO
Patellar Dislocation
The Impact of Tibial Tubercle-trochlear Groove Distance and Patellar Height on the Outcome of Isolated Medial Patellofemoral Ligament Reconstruction
The investigators plan to perform a prospective observational cohort study of patients undergoing MPFL reconstruction for the treatment of episodic patellar instability in the absence of significant degenerative disease.
- Trial name
- TT-TG Outcome (NCT03076008)
- Testing
- Observational
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Minnesota
Hip Osteoarthritis, Avascular Necrosis
Insignia™ Hip Stem Outcomes Study
The objective of this study is to evaluate the safety and effectiveness of the Insignia™ Hip Stem for global market access and post-market clinical follow-up up to 10 years postoperative.
- Conditions
- Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
- Trial name
- NCT05144191
- Testing
- Insignia uncemented Hip Stem
- Where
- 11 sites in United States
- Volunteers
- 313 people
- Sponsor
- Stryker Orthopaedics
Anterior Cruciate Ligament Tear, Osteoarthritis, Knee
Long Term Clinical and Radiographical Outcomes of Different Anterior Cruciate Ligament Reconstruction Techniques
The purpose of this study is to evaluate the long-term results of various anterior cruciate ligament reconstruction techniques. This assessment is necessary for the current context of anterior cruciate ligament research as…
- Trial name
- NCT05088278
- Testing
- Anatomical single bundle ACL reconstruction with hamstrings, Anatomical single bundle ACL reconstruction with patellar tendon, ACL reconstruction with over the top plus lateral plasty technique
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Istituto Ortopedico Rizzoli
Spinal Cord Injuries, Drug Effect
Acute Effects of Pharmacological Neuromodulation on Leg Motor Activity in Patients With SCI Treated With EES
In a current first-in-man study, called Stimulation Movement Overground (STIMO) (NCT02936453; CER-VD: 04-2014; Swissmedic: 2016-MD-0002), epidural electrical stimulation (EES) of the spinal cord is applied to enable individuals…
- Trial name
- STIMO-PHARMA (NCT04052776)
- Testing
- Buspirone, Levodopa-Carbidopa, Buspirone + Levodopa-Carbidopa
- Where
- Switzerland
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Patellar Dislocation
Non-operative Treatment in First-time Patellar Dislocation
Study to evaluate the conservative treatment of patients after their first episode of primary lateral patellar dislocation. Randomized controlled trial with 2 groups: standard treatment (2-weeks with brace) followed by physical…
- Trial name
- NCT06086080
- Testing
- Standard care, Taping
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Fundacion Clinica Valle del Lili
Diabetic Foot Ulcer
Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers
This is a randomized controlled crossover trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating diabetic foot ulcers.
- Trial name
- NCT06938685
- Testing
- Standard of Care, NeoThelium FT
- Where
- 8 sites in United States
- Volunteers
- 132 people
- Sponsor
- NuScience Medical Biologics, LLC
Venous Leg Ulcer, Diabetic Foot
AQUACEL® Ag+ Extra™ vs Cutimed® Sorbact®
Study is to provide a blinded assessment of wound closure status utilizing photographs collected as per standard of care (SOC) during the AAA RCT (WC-22-435).
- Trial name
- NCT07308678
- Where
- Germany
- Volunteers
- 105 people
- Sponsor
- ConvaTec Inc.
Joint Instability, Ankle Sprains
Functional Electrical Stimulation in Chronic Ankle Instability
Individuals with chronic ankle instability (CAI) display neuromuscular deficits such as altered control of posture and gait when compared with healthy controls.
- Conditions
- Joint Instability, Ankle Sprains, Sport Injury
- Trial name
- ESCAIP (NCT04314960)
- Testing
- Functional electrical stimulation device (NESS L300Plus, Bioness, Valencia, CA)
- Where
- Israel
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shmuel Springer
Hip Infection
Relationship Between Preoperative Subcutaneous Trochanteric Fat Thickness and Postoperative Infection Risk
The effect of preoperative subcutaneous trochanteric fat thickness and trochanteric soft tissue thickness on postoperative infection risk in patients undergoing hemiarthroplasty for femoral neck fracture
- Trial name
- NCT06428760
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Femoral Neck Fracture, Osteoarthritis
Dual Mobility Cup in Total Hip Arthroplasty Preventing Dislocation in Patients at Risk
Retrospectively study reviewing 34 patients operated with dual mobility cups in total hip arthroplasty between January 2009 and June 2012 at Sundsvall Hospital.
- Trial name
- NCT01644227
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Sundsvall Hospital
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