Clinical trials: Leg Injuries and Disorders
Patellar Dislocation, Knee Injuries
Blood Flow Restriction Training After Patellar INStability
This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called blood flow restriction training (called BFRT) will improve recovery…
- Conditions
- Patellar Dislocation, Knee Injuries, Leg Injury, Wounds and Injuries
- Trial name
- BRAINS (NCT04554212)
- Testing
- Blood Flow Restriction Training
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- Caitlin Conley
Diabetic Foot
Sealed Therapeutic Shoe as Treatment of Diabetic Foot Ulcers
Total contact casts (TCCs) are effective treatment of plantar diabetic foot ulcers because they effectively offload the ulcer and are non-removable, resulting in high adherence to using the device.
- Trial name
- NCT04085926
- Testing
- Sealed therapeutic shoe, Total contact cast
- Where
- 3 sites in Sweden
- Volunteers
- 4 people
- Sponsor
- Region Örebro County
Medial Tibial Stress Syndrome
Effects of Therapeutic Ultrasound Versus Shockwave Therapy in Medial Tibial Stress Syndrome in Recreational Runners
This project was a Randomized control trial conducted to check the effects of therapeutic ultrasound versus shockwave therapy on pain , range of motion and function in recreational runners with medial tibial stress syndrome so…
- Trial name
- NCT05392036
- Testing
- baseline physical therapy treatment along with shockwave therapy, baseline physical therapy treatment along with therapeutic ultrasound
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Cardiovascular Diseases, Health Behavior
Influence of Walking Pilgrimage on Changes in Body Composition, Biochemical Parameters, Circulatory and Respiratory Efficiency and Foot Biomechanics in Healthy Women and Men of All Ages.
The aim of the study is to assess the health habits and changes in body composition and exercise capacity as well as blood biochemical parameters of people participating in 14-21-day walking pilgrimages.
- Conditions
- Cardiovascular Diseases, Health Behavior, Foot Injuries and Disorders, Skin Condition
- Trial name
- NCT05005832
- Testing
- multi day walking
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Józef Piłsudski University of Physical Education
Cognitive Decline, Delirium
CITADEL: Effectiveness of CITicoline in Preventing Cognitive Decline After DELirium
The aim of this study is to assess whether citicoline (TRAUSAN), a neuroprotective agent involved in membrane phospholipid synthesis and neurotransmission, can prevent or attenuate cognitive decline in older adults who develop…
- Trial name
- CITADEL (NCT07804498)
- Testing
- Citicoline
- Where
- Italy
- Volunteers
- 122 people
- Sponsor
- University of Milano Bicocca
Diabetic Foot Ulcer, Lower Extremity Wound
DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers
This is a prospective, multicenter, clinical research trial evaluating the clinical outcomes of DermACELL AWM in dermal regeneration.
- Trial name
- NCT03044132
- Testing
- DermACELL AWM
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- LifeNet Health
Exuding Wounds, Ulcer, Leg
Clinical Study of Moisture Sensor Dressing Used for Exuding Wounds
Observational prospective study of the clinical use of a wound dressing with a moisture sensor for use on exuding wounds.
- Conditions
- Exuding Wounds, Ulcer, Leg, Wound
- Trial name
- NCT04890769
- Testing
- Moisture sensor wound dressing
- Where
- Sweden
- Volunteers
- 4 people
- Sponsor
- Fredrik Iredahl
Accidental Falls, Bone Fracture
Flooring for Injury Prevention Trial
This study will evaluate the efficacy of novel compliant flooring in reducing injuries due to falls in a long-term care facility, determine the cost effectiveness of this intervention, and assess perceptions about compliant…
- Conditions
- Accidental Falls, Bone Fracture, Traumatic Brain Injury, Head Injuries, Closed
- Trial name
- FLIP (NCT01618786)
- Testing
- SmartCell flooring, Plywood flooring
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Dr. Stephen Robinovitch
Chronic Ankle Instability
Elite Athletes With Chronic Ankle Instability Using Spraino®: A Cohort Study
Fear of re-injury and deficiencies in ankle joint function are common conditions amongst high performance (elite) athletes with chronic ankle instability (CAI), who participate in indoor sports.
- Trial name
- NCT03706729
- Testing
- Spraino
- Where
- 2 sites in Denmark
- Sponsor
- University of Southern Denmark
Diabetic Foot, Diabetic Foot Ulcer
Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers
People with diabetes often experience foot ulcers, which can harm their ability to move, lower their quality of life, and increase the chances of losing a limb.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Foot Wound
- Trial name
- NCT06487780
- Testing
- Lifestyle-focused Occupational Therapy Intervention, Education
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California
Hip Injuries and Disorders, Hip Fractures
Intramedullary Nail Versus Hip Arthroplasty in Unstable Trochanteric Hip Fractures
A hip fracture is a large burden to the patient with increased mortality, pain and increased need for daily assistance. Trochanteric fractures of the femur (FTF) represents about 35% of the hip fractures.
- Trial name
- TUFHIPRCT (NCT04868305)
- Testing
- Intramedullary nail, Hip arthroplasty
- Where
- Norway
- Volunteers
- 170 people
- Sponsor
- Helse Stavanger HF
Diabetic Foot Ulcer, Dehiscence of Amputation Stump
Kerecis Omega3 Wound Plus SOC vs. SOC Alone in Treating Severe Diabetic Foot Ulcers and Forefoot Amputations
This is a prospective, multi-national, multi-centre, randomized, non-blinded (photo evaluation is blinded), controlled clinical investigation in patients suffering from diabetic wounds reaching to tendon, bone, or joint.
- Conditions
- Diabetic Foot Ulcer, Dehiscence of Amputation Stump, Amputation
- Trial name
- Odinn (NCT04257370)
- Testing
- Kerecis™ Omega3 Wound, Standard of care
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Kerecis Ltd.
Osteoarthritis, Hip, Osteonecrosis of Femoral Head
Squeaking in Ceramic-on-Ceramic Total Hip Arthroplasty Using Delta TT Cup
This study will evaluate clinical outcome on patients who undergo ceramic on ceramic (CoC) bearing total hip arthroplasty (THA) using Delta TT cup.
- Conditions
- Osteoarthritis, Hip, Osteonecrosis of Femoral Head, Femoral Neck Fractures, Rheumatoid Arthritis of Hip
- Trial name
- NCT04594564
- Testing
- Total hip arthroplasty with Delta TT cup
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Seoul National University Hospital
Tibial Fractures, Vitamin D Deficiency
Vitamin D Supplementation and Tibia Fracture. Does it Improve Healing Rate?
This study evaluates the effect of Vitamin D3 supplementation in healing rate of tibia fractures in adult patients with low vitamin D.
- Conditions
- Tibial Fractures, Vitamin D Deficiency, Fracture Healing
- Trial name
- ViDco (NCT03232216)
- Testing
- Vitamin D3.
- Where
- Chile
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Hospital del Trabajador de Santiago
ACL - Anterior Cruciate Ligament Deficiency, Varus Deformity of Tibia (Disorder)
Patients With Acl Injury and Varus Knee Will Undergo Acl Reconstruction Alone, or Combined With High Tibial Osteotomy in the Same Session.
The purpose of this study is to compare the results of single-stage anterior cruciate ligament reconstruction combined with high tibial osteotomy and anterior cruciate ligament reconstruction alone in knees with varus…
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, Varus Deformity of Tibia (Disorder), ACL Injury, Knee Deformity
- Trial name
- NCT05817084
- Testing
- medial opening wedge high tibial osteotomy, anterior cruciate ligament reconstruction
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mostafa Hassanein, Msc
Diabetic Foot Ulcer, Non-healing Wound
Debritom - Micro Water Jet Technology and Wound Healing
This study will investigate the clinical efficacy of micro water jet technology in the debridement and healing of chronic lower extremity ulcers.
- Conditions
- Diabetic Foot Ulcer, Non-healing Wound, Non-Healing Ulcer of Skin, Venous Leg Ulcer
- Trial name
- NCT04240574
- Testing
- Debritom
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Stephanie Wu
Lower-limb Orthoses, Frailty/Sarcopenia
Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses
The overall goal of this project is to develop modular, lower-limb, powered orthoses that fit to user-specific weakened joints and control force/torque in a manner that enhances voluntary motion in broad patient populations.
- Conditions
- Lower-limb Orthoses, Frailty/Sarcopenia, Chronic Overuse Musculoskeletal Injuries
- Trial name
- NCT05240014
- Testing
- Modular powered orthosis
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetic Foot Ulcer of Neuropathic Origin
The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Southern Europe The TRANS-South Study
Trafermin is a recombinant human basic fibroblast growth factor (bFGF; original development code, KCB-1), which is manufactured by genetic engineering using Escherichia coli by Kaken Pharmaceutical Co., Ltd. (Tokyo, Japan).
- Trial name
- TRANS-South (NCT01217463)
- Testing
- Trafermin 0.01% spray
- Where
- 24 sites in Czechia, France and 2 more
- Volunteers
- 201 people
- Sponsor
- Olympus Biotech Corporation
Foot Ulcer
Functional Ankle Taping Correction on Plantar Foot Ulcer Healing in Diabetic Patients
This study will investigate the effects of Functional ankle taping correction on plantar foot ulcer healing in diabetic patients.
- Trial name
- NCT06065488
- Testing
- ankle kinesio tap
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- MTI University
Non-healing Wound
Treatment of Wounds Using Oasis® ECM
The purpose of this clinical study is to gather post-market clinical evidence on the use of Oasis ECM as a treatment for donor site wounds in the community setting in the United Kingdom.
- Trial name
- NCT03632031
- Testing
- Oasis Extracellular Matrix, Standard Care (in control arm)
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- Cook Biotech Incorporated