Clinical trials: Leiomyoma
Uterine Fibroid, Endometrial Cyst
Ultrasonographic Appearance of the Endometrium After Ulipristalacetate Use and Endometrial Changes
If endometrial thickening is visualised (>10mm) after the use of ulipristalacetate in case of medical treatment for uterine fibroids a saline infusion and sonographic examination will be performed to evaluate the endometrium and…
- Trial name
- NCT04576039
- Testing
- saline infusion sonography
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Leiomyoma, Fibroids
Establishment of Fibroid Tissue Bank
The purpose of this study is to collect information and tissue samples from women with uterine fibroids. The samples will be used to study genes, proteins and other substances in order to better understand the disease process and…
- Trial name
- NCT00710346
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Fibroids
Uterine Filling Pressure in Hysteroscopy
The aim of the study is to compare the outcomes of patients undergoing hysteroscopy with a MyoSure device with a pressure of 60 mmHg to those using the standard of 80 mmHg.
- Trial name
- NCT04550429
- Testing
- MyoSure Hysteroscopic Morcellator Device
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Northwestern University
Myoma;Uterus
Prevalence of Intrauterine Adhesions After Myomectomy
This prospective, multicenter, observational study evaluated the prevalence of intrauterine adhesions after laparoscopic or laparotomic myomectomy and investigated clinical and surgical factors associated with their occurrence.
- Trial name
- NCT04030273
- Testing
- Diagnostic hysteroscopy
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Università degli Studi dell'Insubria
Uterine Fibroids (MeSH Heading: Leiomyoma)
A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia
Multi-center, randomized, double-blind, parallel-group study to confirm non-inferiority of KLH-2109 to Leuprorelin acetate in uterine fibroids patient with menorrhagia
- Trial name
- NCT05440383
- Testing
- KLH-2109, Leuprorelin
- Where
- Japan
- Volunteers
- 287 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Uterine Leiomyomata (Fibroids)
Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRA-027 in Japanese Postmenopausal Women
The primary purpose of this study is to assess the safety and tolerability of ascending, multiple, oral doses of PRA-027 in Japanese postmenopausal women.
- Trial name
- NCT00826436
- Where
- Japan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Cervix Neoplasms, Endometrial Cancer
Comparison of the Effects of Fentanyl, Oxycodone, Butorphanol on Gastrointestinal Function
Postoperative ileus (POI) is a transient loss of coordinated peristalsis precipitated by surgery and exacerbated by opioid pain medication.So,how to provide patients with ideal analgesia without affecting the recovery of…
- Conditions
- Cervix Neoplasms, Endometrial Cancer, Adenomyosis, Fibroid Uterus
- Trial name
- NCT04295109
- Testing
- the drug of intravenous patient-controlled analgesia
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Fibroid Uterus, Metrorrhagia
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms…
- Conditions
- Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
- Trial name
- STORY (NCT06802198)
- Testing
- total hysterectomy, subtotal hysterectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Uterine Myoma
Barbed Suture in Single-port Laparoscopic Myomectomy
The aim of this study is to test our hypothesis that the use of unidirectional knotless barbed suture in single-port laparoscopic myomectomy could facilitate the suture of uterine wall defect after myoma enucleation as multi-port…
- Trial name
- NCT01984632
- Testing
- Single-port laparoscopic myomectomy, Multi-port laparoscopic myomectomy
- Where
- 4 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- CHA University
Uterine Fibroids (UF)
Investigating the Optimal Remifentanil and Dexmedetomidine Concentration for Uterine Fibroid Ablation
This clinical trial aims to find a better drug concentration of Remifentanil in Uterine Fibroid Ablation. The main question it seeks to answer is: [primary hypothesis 1] Remifentanil concentration of 2.0 ng/mL provides better…
- Trial name
- NCT06640738
- Testing
- arm 2, arm 1
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Medical University
Pregnancy Related, Pregnancy Complications
Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring
The Relugolix Pregnancy Registry is a prospective, observational cohort study designed to evaluate the association between relugolix-containing therapy exposure during pregnancy and subsequent maternal, fetal, and infant…
- Conditions
- Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk
- Trial name
- NCT05739123
- Testing
- Relugolix-Containing Product
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Fibroid Uterus, Polyp Uterus
Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient Settings
This is an observational prospective monocentric study which aims to compare operative hysteroscopies performed in the operating room under general or loco-regional anesthesia and those performed outside the operating room…
- Conditions
- Fibroid Uterus, Polyp Uterus, Retained Products of Conception
- Trial name
- NCT07146659
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Fibroid
Ulipristal Acetate Versus GnRH Analogue Treatment Before Hysteroscopic Resection of Uterine Leiomyoma
The uterine leiomyoma is the most common female benign disease. Submucosal fibroid are about 10%, they distort the endometrial cavity causing heavy and/or irregular bleeding (AUB) and infertility.
- Trial name
- NCT02361879
- Testing
- ulipristal acetate, Leuprolide acetate
- Where
- Italy
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Uterine Fibroids
Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids
To determine the safety, pharmacokinetics and efficacy of 4 doses (3, 6, 12, 24 mg) of Proellex in premenopausal women with uterine fibroids confirmed by ultrasound. Drug will be administered vaginally.
- Trial name
- NCT01451424
- Testing
- Proellex
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Repros Therapeutics Inc.