Clinical trials: Lens Disease
Cataract
The Usefulness of Visuprime in Cataract Surgery
This is a multicentre, post-market, open label, randomized, placebo-controlled prospective study exploring the performance of Visuprime in improving ocular surface homeostasis and reducing conjunctival bacterial load in patients…
- Trial name
- NCT06533995
- Testing
- Visuprime
- Where
- 2 sites in Italy
- Volunteers
- 75 people
- Sponsor
- VISUfarma SpA
Migraine
Optical Treatment of Migraines Using the Avulux™ Optical Filter in the Form of Spectacle Lenses.
The primary objective of this study is to evaluate the efficacy of the Avulux device in reducing the impact of migraine headaches as measured by improvement in Headache Impact Test (HIT-6TM) scores at three weeks when compared to…
- Trial name
- NCT03902496
- Testing
- HIT-6 Questionnaire, Avulux Spectacles
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Avulux, Inc.
Dry Eye, Dry Eye Syndromes
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Tangible Hydra-PEG is a novel coating technology designed to improve lens wettability, deposit resistance, and tear film breakup time.
- Trial name
- NCT03417505
- Testing
- Scleral lenses treated with Tangible Hydra-PEG, Untreated scleral lenses
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Tangible Science
Visual Disorder
Clinical Evaluation of Approved and Investigational Contact Lenses
This study is a multi-site, 5-visit dispensing, bilateral double-arm parallel group design, double-masked clinical trial using an investigational contact lens and a marketed contact lens.
- Trial name
- NCT02669095
- Testing
- Investigational Contact Lenses (Test), Marketed Contact Lenses (Control)
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Lens Implantation, Intraocular
Evaluation of Safety and Performance Outcomes of Eyedeal IOL Implantation After Cataract Removal
A cataract is the clouding of the natural lens in the eye and is very common as when getting older. A cloudy lens makes it difficult to see.
- Trial name
- NCT05776095
- Testing
- Cataract surgery, Eyedeal® Model PX65AS1 IOL
- Where
- 2 sites in Germany, Lithuania
- Volunteers
- 97 people
- Sponsor
- Xi'an Eyedeal Medical Technology Co., Ltd
Myopia
Study of Viziatek ISL™ Refractive Phakic Intra Sulcus Lens for Refraction Adjustment in Blind Volunteers
This is a clinical investigation. A total of up to 5 subjects, but not less than 3 at one investigational site will undergo insertion of the ISL in one eye and will be followed through 6 months postoperative.
- Trial name
- NCT05518344
- Testing
- Viziatek ISL™ (hereinafter referred to as the "ISL") implanted in blind eye.
- Where
- Latvia
- Volunteers
- 4 people
- Sponsor
- Hanita Lenses
Cataract, Pain
LE Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Loteprednol Etabonate Ophthalmic Gel, (BID and TID) versus Vehicle Group for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery.
- Conditions
- Cataract, Pain, Ocular Inflammation
- Trial name
- NCT02786901
- Testing
- Loteprednol Etabonate Ophthalmic Gel dosed TID, Loteprednol Etabonate Ophthalmic Gel dosed BID, Vehicle Gel
- Where
- 6 sites in United States
- Volunteers
- 600 people
- Sponsor
- Bausch & Lomb Incorporated
Non-Proliferative Diabetic Retinopathy, Cataract
Nepafenac Once Daily for Macular Edema - Study 2
The purpose of this study is to demonstrate superiority of Nepafenac Ophthalmic Suspension, 0.3% dosed once daily relative to Nepafenac Vehicle based upon clinical outcomes among diabetic participants following cataract surgery.
- Trial name
- NCT01872611
- Testing
- Nepafenac Ophthalmic Suspension, 0.3%, Vehicle, Prednisolone acetate
- Volunteers
- 819 people
- Sponsor
- Alcon Research
Astigmatism
Comparison of Comfilcon A Toric Contact Lenses and Samfilcon A Toric Contact Lenses
The objective of this study is to evaluate the subjective acceptance of comfilcon A toric contact lens, compared to samfilcon A toric lens.
- Trial name
- NCT03519932
- Testing
- comfilcon A toric lens, samfilcon A toric lens
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- CooperVision, Inc.
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Cataract
Cataract Surgery: Femto LDV Z8 Versus Conventional
The aim of the study is to demonstrate the performance and safety of the Femtosecond laser-assisted anterior capsulotomy and lens fragmentation on human eyes using the FEMTO LDV Z8 compared to conventional technique in cataract…
- Trial name
- COMFORT (NCT02351271)
- Testing
- Femto LDV Z8, Manual capsulorhexis&lens fragmentation
- Volunteers
- 130 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Refractive Error, Cataract
Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions
Purpose of The Study: The purpose of this study is the following: A)To gather age-related normative visual acuity data for the Vimetrics Central Vision Analyzer (CVA, Vimetrics, LLC, Media, Pa) B)To gather visual acuity data for…
- Conditions
- Refractive Error, Cataract, Maculopathy
- Trial name
- NCT02028351
- Where
- 2 sites in United States, Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sinclair Technologies, LLC
Cataract
Clinical Investigation of Omega Refractive Capsule Model V With Use of an FDA Approved IOL
The objective of this study is to evaluate the safety and effectiveness of the investigational Omega Refractive Capsule (model V)
- Trial name
- ORCV (NCT04574102)
- Testing
- Omega Refractive Capsule with FDA approved Intraocular Lens, FDA approved Intraocular lens
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Glaucoma, Cataract
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination
The goal of this clinical trial is to further observe and learn if the SpyGlass Pharma Bimatoprost Implant System / IOL Combination works to treat cataracts and either ocular hypertension or glaucoma.
- Conditions
- Glaucoma, Cataract, Ocular Hypertension
- Trial name
- NCT07154810
- Where
- Honduras
- Volunteers
- 23 people
- Sponsor
- SpyGlass Pharma, Inc.
Juvenile Myopia, Myopia
Assessment of DOT Spectacles in Chinese Children
This is a randomized, controlled, evaluator-blinded, multicenter, two-arm parallel group clinical trial to evaluate the continued safety and efficacy of Diffusion Optics Technology (DOT) spectacle lenses by comparing to single…
- Trial name
- CATHAY (NCT05562622)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 5 sites in China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Cataract, Lens Opacity
Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707)
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacity, Presbyopia
- Trial name
- NCT03688399
- Testing
- IOL implantation experimental, IOL implantation comparator
- Where
- Hungary
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Hyperopia, Myopia
Clinical Study of Visibility Tinted Clariti Contact Lens
The purpose of this study was to investigate the safety and efficacy of the Sauflon Clariti Monthly silicone hydrogel contact lenses with handling tint (Sauflon Pharmaceuticals Limited) by comparison with Air Optix Aqua silicone…
- Trial name
- NCT01996787
- Testing
- Air Optix Aqua, Clariti with Handling Tint
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sauflon Pharmaceuticals Ltd
Presbyopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The primary objective of this study is to demonstrate noninferiority in visual acuity at distance when wearing the test contact lenses (LID210464) compared to the control contact lenses (AOHG MF) after 30 days of wear.
- Trial name
- NCT05338333
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
- Where
- 8 sites in United States
- Volunteers
- 101 people
- Sponsor
- Alcon Research
Myopia, Myopia Progression
Comparing Myopia Control Spectacle Lenses and Standard Single Vision Spectacle Lenses in Children With Myopia
The purpose of this clinical trial is to compare a new myopia control spectacle lens with a standard single vision spectacle lens in slowing the progression of myopia (nearsightedness) in healthy children aged 6 to under 11…
- Trial name
- PEARL (NCT07839091)
- Testing
- Investigational Myopia Control Spectacle Lens, Single Vision Spectacle Lens
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Cataracts
Contralateral ReSTOR / Monofocal or Phakic Eye
Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.
- Trial name
- NCT00731640
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alcon Research
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