Clinical trials: Lens Disease
Vision Disorders
Clinical Evaluation of Two Silicone Hydrogel Daily Disposable Contact Lenses
The purpose of this investigation is to evaluate the short-term, clinical performance of two silicone hydrogel daily disposable contact lenses.
- Trial name
- NCT02595502
- Testing
- JJVC Marketed Contact Lens (Test), Competitor Marketed Contact Lens (Control)
- Where
- 13 sites in United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Study to Evaluate the Safety and Efficacy of a New Silicone Hydrogel Contact Lens Design
The objective of this study is to evaluate the safety and efficacy of a new silicone hydrogel contact lens compared to the Bausch + Lomb PureVision contact lens when worn by adapted soft contact lens wearers.
- Trial name
- NCT01449526
- Testing
- B&L Investigational Contact Lens, B&L PureVision Contact Lens
- Volunteers
- 166 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia, Corneal Astigmatism
Evaluation of the Safety and Performance of the HARMONI® Toric Lens
The purpose of this study was to evaluate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic (HMTIOL) in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Aphakia, Corneal Astigmatism, Cataract
- Trial name
- NCT03050697
- Testing
- HARMONI® Modular Toric Intraocular Lens, Cataract extraction with intraocular lens (IOL) implantation
- Where
- New Zealand
- Volunteers
- 16 people
- Sponsor
- ClarVista Medical
Cataract
Comparison of Viusal Outcomes After Implantation of the POD 26% FineVision Toric (PhysIOL) and POD 26% Toric (PhysIOL)
The study is an observational non-randomised controlled study comparing the visual acuity after implantation of the POD 26% FINEVISION TORIC with respect to the POD 26% TORIC
- Trial name
- NCT02426385
- Testing
- FineVision Toric
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery
The purpose of this study is to determine the efficacy and safety assessment of T2380 for mydriasis and anaesthesia in phacoemulsification cataract surgery versus reference group (topical mydriatics and anaesthetic) 2X246…
- Trial name
- NCT02101359
- Testing
- T2380, Mydriatics, Tetracaine
- Where
- France
- Volunteers
- 609 people
- Sponsor
- Laboratoires Thea
Dry Eye Disease, Cataract
Systane Hydration in Subjects Undergoing Cataract Surgery
The primary objective of this study is to demonstrate reduced corneal staining with use of Systane Hydration among subjects with dry eye disease (DED) undergoing routine cataract removal and monofocal intraocular lens (IOL)…
- Trial name
- NCT05056233
- Testing
- Systane Hydration lubricant eye drops
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Pain, Inflammation
Efficacy of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery
This is an efficacy study of Bromfenac Ophthalmic Solution in cataract surgery.
- Conditions
- Pain, Inflammation, Cataract
- Trial name
- NCT01367249
- Testing
- Bromfenac Ophthalmic Solution
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
Performance of Two Daily Disposable Multifocal Contact Lenses
This study will compare the performance of two daily disposable multifocal soft contact lenses.
- Trial name
- NCT07444658
- Testing
- Lens A (kalfilcon A), Lens B (stenfilcon A)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CooperVision International Limited (CVIL)
Dry Eye Syndromes, Cataract
A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms
This study will evaluate the effect of sodium carboxymethylcellulose eye drops in the treatment of dry eye after cataract surgery.
- Trial name
- RLOTUS (NCT02028754)
- Testing
- Sodium Carboxymethylcellulose, Levofloxacin, Prednisolone
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Allergan
Cataract
Check of Optical Features and Accuracy of the Zeiss ZO Lens After Selection and Calculation With OKULIX
It is planned to implant the intraocular lenses XL Stabi ZO and Invent ZO into the eyes of patients for whom a cataract operation is medically indicated. The lenses are marketed and CE certified.
- Trial name
- ZO Okulix (NCT00842959)
- Testing
- Invent ZO, XL Stabi ZO
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Carl Zeiss Meditec AG
Myopia
Essilor® Stellest® Lenses Multicentre European Study (SLOMES)
The goal of this post-market clinical follow up Study is to demonstrate the efficacy, safety, acceptability, and quality of life implications of Essilor® Stellest® spectacle lenses in slowing myopia progression in European…
- Trial name
- SLOMES (NCT06263946)
- Testing
- Essilor® Stellest® spectacle lenses
- Where
- 3 sites in France, Ireland and 1 more
- Volunteers
- 150 people
- Sponsor
- Essilor International
Refractive Error
Lubricity Post-Wear - Competitive Lenses Pilot
The purpose of this study is to measure the coefficient of friction of three silicone hydrogel, daily disposable contact lenses after 16 hours of wear.
- Trial name
- NCT02402127
- Testing
- Narafilcon A contact lenses, Stenfilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Allergic Conjunctivitis
Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in Allergic Conjunctivitis
The purpose of this study is to evaluate the efficacy and safety of an anti-allergy drug with a contact lens compared to placebo in preventing ocular itching associated with allergic conjunctivitis
- Trial name
- NCT00432757
- Testing
- Ketotifen with a Contact Lens (generic name not yet established)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Vistakon Pharmaceuticals
Refractive Error
Evaluation of Deposits on Contact Lenses Worn Daily Wear
The purpose of this study was to measure front surface deposits on contact lenses when worn for ten hours.
- Trial name
- NCT00725153
- Testing
- Balafilcon A contact lenses (PureVision), Etafilcon A contact lenses (Acuvue2)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Primary Angle Closure Glaucoma, Primary Angle Closure
Hydrus Microstent and Lens Extraction for the Treatment of Primary Angle-Closure Glaucoma
This study is a prospective evaluation of the Hydrus Microstent for the treatment of Primary Angle Closure (PAC) and Primary Angle Closure Glaucoma (PACG) with adjunctive cataract.
- Trial name
- NCT04622605
- Testing
- Trabecular bypass and Schlemm's canal stent
- Where
- Philippines
- Volunteers
- 31 people
- Sponsor
- Asian Eye Institute
Myopia, Hyperopia
Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers
The purpose of this study was to compare the clinical performance of two different reusable lenses in habitual spherical soft lens wearers.
- Trial name
- NCT06098339
- Testing
- Lens A (fanfilcon A), Lens B (lotrafilcon B)
- Where
- 3 sites in United States, Canada
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT02553681
- Testing
- roflufocon D contact lenses, RGP contact lenses made from roflufocon D
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Cataract
Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1
The objective of this study is to prospectively evaluate the visual parameters in a series of patients after phacoemulsification cataract surgery in a series of patients bilaterally implanted with the AcrySof® ReSTOR® Aspheric…
- Trial name
- NCT00710931
- Testing
- AcrySof ReSTOR Aspheric IOL model SN6AD1
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Cataracts
An Assessment of Residual Spherical Aberration, Postoperative Total High Order Aberrations, and Functional Vision Correlation Following Intraocular Lens (IOL) Implantation
The purpose of this study was to evaluate total residual spherical aberration (TSA) post-IOL implantation, and to determine if an association exists between TSA, postoperative high order aberrations (HOA), and functional vision…
- Trial name
- NCT01190631
- Testing
- Acrysof IQ (SN60WF) IOL
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alcon Research
Aphakia, Cataract
Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism
The objective of this study is to evaluate uncorrected distance vision and quality of vision as measured by the McAlinden QoV questionnaire 3 months following the final lock-in treatment of the implanted RxSight Light Adjustable…
- Trial name
- NCT03729024
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 21 people
- Sponsor
- RxSight, Inc.
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