Clinical trials: Lens Disease
Astigmatism
Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear
This is a prospective, multi-site, 4-visit, bilateral, dispensing, randomized, controlled, double-masked, 2x2 crossover study to evaluate subjective comfort, overall opinion and end of day comfort following wear of two different…
- Trial name
- NCT06749496
- Testing
- Test Lens, Control Lens
- Where
- 12 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Corneal Ulcer, Persistent Corneal Epithelial Defect
Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Trophic Ulcers
The purpose of this open, multicenter pilot trial is to assess the impact of the use of an amniotic membrane on the healing of a persistent epithelial lesion or of a corneal ulcer.
- Trial name
- NCT05172349
- Testing
- LV-Visio-AMTRIX
- Sponsor
- TBF Genie Tissulaire
Myopia
Clinical Comparison of Two Daily Disposable Silicone Hydrogel Soft Contact Lens
The objective of this study is to evaluate a new daily disposable silicone hydrogel soft contact lens by comparing to an existing daily disposable soft contact lens.
- Trial name
- NCT02676258
- Testing
- Si-Hy (olifilcon B), Vistakon (narafilcon A)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Visco Vision Inc.
Refractive Errors
Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05431478
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Assessment of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of LID018869 soft contact with ACUVUE® OASYS with HYDRACLEAR® PLUS (AOHP) soft contact lenses over 30 days of daily wear.
- Trial name
- NCT05050578
- Testing
- Lehfilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 10 sites in United States
- Volunteers
- 166 people
- Sponsor
- Alcon Research
Aphakia
Feasibility Study of an Accommodating IOL Design
The purpose of this clinical study is to assess safety and explore usability and effectiveness of the test product, AAL-FAIOL. This study will be conducted in Central America.
- Trial name
- NCT07147192
- Testing
- AAL-FAIOL, BAL-FAIOL, Phacoemulsification
- Where
- 4 sites in Costa Rica, Dominican Republic and 2 more
- Volunteers
- 17 people
- Sponsor
- Alcon Research
Cataract, Cataract Senile
Prospective Evaluation of the Tecnis Symfony Intraocular Lens (IOL)
Advances in cataract surgery and premium IOLs have allowed the ophthalmologist and optometrist to embrace the fact, as with Lasik patients, that refractive cataract surgery can allow their patients to be potentially free or less…
- Trial name
- NCT03579368
- Testing
- Symfony implantation
- Volunteers
- 200 people
- Sponsor
- Kovach Eye Institute
Cataract
Clinical Evaluation of the FluidVision Accommodation Intraocular Lens (AIOL)
The objective of this study is to evaluate the safety and effectiveness of an investigational IOL in providing a range of vision as compared to a commercially available trifocal IOL in subjects undergoing cataract extraction and…
- Trial name
- CLEAR (NCT03508778)
- Testing
- FluidVision AIOL, AcrySof IQ PanOptix Trifocal IOL, Cataract surgery
- Where
- South Africa
- Volunteers
- 95 people
- Sponsor
- PowerVision
Cataract
Nepafenac Compared to Placebo for Ocular Pain and Inflammation
The purpose of this study was to demonstrate that Nepafenac Ophthalmic Suspension, 0.1% is superior to Nepafenac Vehicle (placebo) for the prevention and treatment of ocular inflammation and pain associated with cataract surgery…
- Trial name
- NCT01426854
- Testing
- Nepafenac Ophthalmic Suspension, 0.1%, Nepafenac Vehicle Ophthalmic Solution
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Alcon Research
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of Performing 0.50 Diopter Astigmatism Correction on the Commercially Available RxSight Light Adjustable Lens (LAL)
The primary objective of this study is to evaluate the safety and effectiveness of performing 0.50 D cylinder correction on the RxSight Light Adjustable Lens (LAL) in patients who have undergone implantation with the FDA…
- Trial name
- NCT04005586
- Testing
- Light Delivery Device (LDD)
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- RxSight, Inc.
Cataract, Dry Eye Disease
The Influence of PRN Omega-3 Nutritional Supplement on Visual Acuity
This is a randomized, masked, placebo controlled study to assess the effect on visual acuity, if any, of the PRN omega-3 nutritional supplement in subjects undergoing cataract surgery.
- Trial name
- NCT02260973
- Testing
- Omega-3 (Triglyceride form)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Physician Recommended Nutriceuticals
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Clariti contact lenses.
- Trial name
- NCT03888482
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 154 people
- Sponsor
- Alcon Research
Cataract
Check of Optical Features and Accuracy of the Zeiss ZO Lens After Selection and Calculation With OKULIX
It is planned to implant the intraocular lenses XL Stabi ZO and Invent ZO into the eyes of patients for whom a cataract operation is medically indicated. The lenses are marketed and CE certified.
- Trial name
- ZO Okulix (NCT00842959)
- Testing
- Invent ZO, XL Stabi ZO
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Investigation of AcrySof® IQ PanOptix™ Presbyopia-Correcting Intraocular Lens (IOL) Model TFNT00
The purpose of this study is to investigate visual outcomes and assess safety at 12 months (330-420 days) post bilateral implantation of the AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL.
- Trial name
- NCT02529488
- Testing
- AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL
- Volunteers
- 167 people
- Sponsor
- Alcon Research
Myopia
To Evaluate the Efficacy and Safety of Aspherical Soft Contact Lens in Myopia Control
The objective of this study is to demonstrate that the Ticon Aspherical Daily Disposable Soft Contact Lens could retard myopia progress in youth
- Trial name
- NCT04238897
- Testing
- soft contact lens
- Volunteers
- 72 people
- Sponsor
- APP Vision Care Inc.
Myopia
A Study to Evaluate the Product Performance of a New Silicone Hydrogel Contact Lens
The objective of this study is to evaluate the product performance of a new silicone hydrogel soft contact lens when worn by current soft contact lens wearers on a daily wear basis.
- Trial name
- NCT01873846
- Testing
- Silicone Hydrogel Contact Lens
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
To Evaluate the Efficacy and Safety of Multifocal Soft Contact Lens in Myopia Control
The objective of this study is to investigate the efficacy and safety of soft lens in myopia control.
- Trial name
- NCT03413085
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Largan Medical Co., Ltd.
Ocular Graft-versus-host Disease
Safety and Efficacy of Pro-ocular™ 1% in Daily Scleral Lens Wearing Patients With Ocular Graft-versus-Host Disease
This clinical study seeks to evaluate the safety and efficacy of Pro-ocular™1% topical gel in patients with ocular Graft-versus-Host Disease who wear scleral lenses daily.
- Trial name
- NCT04769648
- Testing
- Pro-ocular™ Topical Gel 1%
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Glia, LLC
Ametropia
Ocular Responses to Short and Long-term Lens Wear
The purpose of this study was to determine whether ocular surface sensitivity to pneumatic, mechanical and chemical stimulation would be affected by the use of the combination of a specific silicone hydrogel lens material with…
- Trial name
- NCT00722891
- Testing
- Purevision Lenses with ReNu Multiplus, Purevision Lenses with Optifree RepleniSH
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error
Clinical Performance of a Silicone Hydrogel for Daily Disposable Wear
The purpose of this study is to compare the visual acuity of an investigational silicone hydrogel to a commercially available silicone hydrogel in contact lens wearers.
- Trial name
- NCT03095027
- Testing
- FID122819 contact lenses, Stenfilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
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