Clinical trials: Lens Disease
Astigmatism
A Clinical Performance of Two Soft Toric Contact Lenses
The study objective was to gather short-term clinical performance data for two soft toric contact lenses.
- Trial name
- NCT05633082
- Testing
- Lens 1 (omafilcon B), Lens 2 (fanfilcon A)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Open-angle Glaucoma
Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract
To evaluate the safety and efficacy of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate open angle glaucoma.
- Trial name
- NCT00721968
- Testing
- Glaucoma Stent Surgery (GTS400 Stent), cataract surgery alone
- Volunteers
- 62 people
- Sponsor
- Glaukos Corporation
Cataract
Clinical Safety and Efficacy of Hydrophilic Acrylic Intraocular Lenses
Clinical safety and efficacy of CT ASPHINA 409 IOLs after implantation
- Trial name
- UVEA409 (NCT03145103)
- Testing
- CT ASPHINA 409
- Where
- Sweden
- Volunteers
- 282 people
- Sponsor
- Carl Zeiss Meditec AG
Myopia
Clinical Evaluation of Two Daily Disposable Silicone Hydrogel Contact Lenses
The purpose of this crossover study was to evaluate the end-of-day comfort of two commercially available, daily disposable, silicone hydrogel contact lenses.
- Trial name
- NCT01561560
- Testing
- Delefilcon A contact lenses, Narafilcon A contact lenses
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Alcon Research
Cataract and IOL Surgery
Development of Optical Biometer
The Helioscope (Cassini Technologies B.V.) is a novel device under development that aims at combining LED-based corneal topography and SS-OCT to provide accurate and fast measurements of both the corneal shape and the ocular…
- Trial name
- CH-0203 (NCT07325162)
- Testing
- New Investigational Optical Biometer (Device), Comparator Device A (Cassini Ambient), omparator Device B (Argos)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cassini Technologies
Cataract
India PanOptix Post Marketing Study
The purpose of this Post Marketing Study is to study the safety and effectiveness of the ACRYSOF IQ PanOptix intraocular lens (IOL) in an Indian population.
- Trial name
- NCT03706066
- Testing
- Acrysof IQ PanOptix IOL, Cataract surgery
- Where
- 5 sites in India
- Volunteers
- 80 people
- Sponsor
- Alcon Research
Refractive Error
AIR OPTIX® COLORS Registration Trial
The purpose of this study was to evaluate the subjective and objective performance and the physiological response to AIR OPTIX® COLORS soft contact lenses compared with AIR OPTIX® AQUA contact lenses in participants with normal…
- Trial name
- NCT01440322
- Testing
- Lotrafilcon B contact lens with color, Lotrafilcon B contact lens
- Volunteers
- 150 people
- Sponsor
- CIBA VISION
Cataract
Safety and Efficacy of FLACS With the FEMTO LDV Z8 Laser Compared to Conventional Cataract Surgery in Chinese Patients
This trial will be designed as a multi-center randomized non-inferiority clinical trial to demonstrate safety and efficacy of the FEMTO LDV Z8 laser for cataract surgery in a Chinese population in China compared to the…
- Trial name
- Z8CAT01 (NCT03953053)
- Testing
- Femtosecond Laser Assissted Cataract Surgery
- Where
- Switzerland
- Volunteers
- 132 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Myopia
Dispensing Evaluation of Printed Etafilcon A With Polyvinylpyrrolidone (PVP)
The purpose of this study is to evaluate the lens fit (mechanical and cosmetic lens fit) of the printed etafilcon A with polyvinylpyrrolidone (PVP).
- Trial name
- NCT01180777
- Testing
- etafilcon A (A), etafilcon A (B), etafilcon A (C)
- Where
- 6 sites in United States
- Volunteers
- 95 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Allergic Conjunctivitis
Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
The purpose of this study is to evaluate the safety of a novel contact lens in healthy normal volunteers
- Trial name
- NCT00569777
- Testing
- K-Lens (generic name not established) and Ketotifen
- Where
- 3 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Vistakon Pharmaceuticals
Cataract
A Prospective Single Center Clinical Study for Capsulotomy Using the LenSx 550 Laser
The LenSx 550 laser system is a femtosecond laser intended for use in performing anterior capsulotomy during cataract surgery. The anterior capsulotomy creates a circular opening in the anterior surface of the capsular bag that…
- Trial name
- NCT00959322
- Testing
- LenSx 550 Laser System
- Where
- Hungary
- Volunteers
- 60 people
- Sponsor
- LenSx Lasers Inc.
CORNEAL EDEMA
Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal Edema
The Hyper-CL™ lenses are indicated for therapeutic use as a bandage to protect the corneal surface and to relieve corneal pain in the treatment of acute or chronic ocular pathologies, such as bullous keratopathy, corneal…
- Trial name
- NCT02660151
- Testing
- Hyper-CL™ lens, Regular soft contact lens, Salt solution
- Where
- 4 sites in Israel, Poland
- Volunteers
- 68 people
- Sponsor
- Eye-yon Medical
Astigmatism, Refractive Errors
Clinical Comparison of Toric Contact Lenses Fit Characteristics
The purpose of this study is to compare the fit characteristics between four Alcon commercially available toric contact lenses.
- Trial name
- NCT05805345
- Testing
- Delefilcon A toric soft contact lens, Lehfilcon A toric soft contact lens, Lotrafilcon B toric soft contact lens
- Where
- 7 sites in United States
- Sponsor
- Alcon Research
Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes
CDL Validation Study
Ocular surface photography is significantly limited in standardization and reproducibility. This reduces its applicability for clinical monitoring of acute or chronic disease.
- Conditions
- Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes, Limbal Stem-cell Deficiency, Eye Lesion
- Trial name
- NCT05461469
- Where
- Austria
- Volunteers
- 104 people
- Sponsor
- Occyo GmbH
Myopia
Evaluation of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses developed by Bausch + Lomb.
- Trial name
- NCT01309880
- Testing
- Test lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder)
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
The goal of this clinical trial is to learn if a new contact lens device can record patterns in eye pressure for 24 hours in adults with glaucoma and in healthy participants.
- Conditions
- Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Ocular Hypertension, Ocular Hypertension (OH)
- Trial name
- NCT06689696
- Testing
- miLens system
- Where
- 3 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Smartlens, Inc.
Contact Lens Fit, Myopia
Clinical Performance of a Silicone Hydrogel Lens With Use of FID 114675A
The purpose of this study is to evaluate the clinical performance of a silicone hydrogel contact lens when used with an investigational multi-purpose disinfecting solution (MPDS).
- Trial name
- NCT01240135
- Testing
- FID 114675A multi-purpose disinfecting solution (MPDS), renu fresh Multi-Purpose Solution (MPS), Galyfilcon A contact lenses (Acuvue Advance)
- Volunteers
- 89 people
- Sponsor
- Alcon Research
Cataract
A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery
A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery
- Trial name
- NCT05550350
- Testing
- Dexycu
- Sponsor
- EyePoint Pharmaceuticals, Inc.
Myopia
Wearability of and Myopia Progression With ZEISS MyoCare Spectacle Lenses
This is a clinical trial evaluating the wearability and effectiveness of three types of ZEISS spectacle lenses in controlling myopia progression.
- Trial name
- NCT07021560
- Testing
- ZEISS MyoCare spectacle lenses, ZEISS SV RX SPH 1.5, ZEISS Clearview
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZEISS Vision Care
Myopia
Soft Lens Study: Biomedics 1 Day Extra Sphere and Clariti 1 Day Sphere
The aim of this study is to evaluate and compare the performance of two soft contact lenses.
- Trial name
- NCT06817785
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
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