Clinical trials: Lens Disease
Meibomian Gland Dysfunction
Contact Lens Comfort Relative to Meibomian Gland Status
This trial aims to establish a correlation between patient reported comfort while using soft contact lenses and meibomian gland dysfunction (MGD).
- Trial name
- NCT01819194
- Testing
- senofilcon A
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Effect of Blue Light Filtration on Visual Performance
The purpose of this study is to evaluate photostress recovery with blue light filter clip-on glasses among pseudophakes [ie, subjects in which the natural lens of the eye has been replaced with an artificial lens (intraocular…
- Trial name
- NCT01938989
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses
- Volunteers
- 158 people
- Sponsor
- Alcon Research
Myopia
Clinical Evaluation of Reusable Soft Contact Lenses
The purpose of this study was to confirm the clinical performance of a novel manufacturing process for comfilcon A contact lenses in habitual wearers over a one-month period of lens wear.
- Trial name
- NCT06119191
- Testing
- Control Lenses (comfilcon A with current process), Test Lenses (comfilcon A with novel process)
- Where
- 5 sites in United States
- Volunteers
- 77 people
- Sponsor
- CooperVision International Limited (CVIL)
Ametropia
A Clinical Study of the Comfilcon A Asphere Soft Contact Lens in Users of Digital Devices
The aim of this work is to investigate the clinical performance and subjective acceptance of the comfilcon A asphere contact lens when compared to single-vision spectacles in subjects who have never worn contact lenses and who…
- Trial name
- NCT04067050
- Testing
- comfilcon A asphere, Spectacles
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Contact Lens-Induced Corneal Disorder of Both Eyes (Diagnosis)
Corneal Oxygen Uptake With Apioc Contact Lenses
The purpose of this research is to determine if a new investigational contact lens shape allows the eye to get more oxygen.
- Trial name
- NCT04031118
- Testing
- Apioc Contact Lens
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Cataract
Visual Function After Implantation of AcrySof® Toric Lens
The objective of this study is to evaluate the postoperative visual function of Taiwanese patients following bilateral or unilateral AcrySof Toric Intraocular Lens (IOL) implantation.
- Trial name
- NCT01074606
- Testing
- AcrySof Toric Intraocular Lens
- Where
- Taiwan
- Volunteers
- 56 people
- Sponsor
- Alcon Research
Cataract
Clinical Study to Evaluate the Safety and Performance of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens in Subjects Undergoing Cataract Extraction
The objective of the study is to evaluate the safety and performance of the enVista trifocal intraocular lens when implanted in the capsular bag.
- Trial name
- NCT04224155
- Testing
- enVista MX60EFH trifocal intraocular lenses (IOLs), enVista MX60E monofocal intraocular lenses (IOLs)
- Where
- 9 sites in Canada
- Volunteers
- 165 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Non-dispensing Fitting Study Comparing the Clinical Performance Hydrogel Sphere Design Contact Lenses.
The aim of this non-dispensing study is to evaluate the clinical performance of different hydrogel contact lens designs.
- Trial name
- NCT02727816
- Testing
- filcon IV I (BC 8.6), filcon IV I (BC 8.7), ocufilcon D
- Where
- Mexico
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract, Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome
An assessment of the surgical performance of DisCoVisc compared to Healon5 during cataract surgery with intraocular lens implantation where miotic/small pupils or intraoperative Floppy Iris Syndrome exists.
- Trial name
- NCT00711347
- Testing
- DisCoVisc, Healon5
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Alcon Research
Cataract
Comparison Between a Toric Monofocal and Multifocal Intraocular Lens
The primary objective of the study is to observe the rotational stability of the implant 30 minutes, one day, 6 weeks, 6 months and 12 months after the implant surgery.
- Trial name
- NCT04907318
- Testing
- Cataract surgery
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Beaver-Visitec International, Inc.
Myopia, Hyperopia
Daily Disposable Performance of 1•DAY ACUVUE® TruEye™ and 1•DAY ACUVUE® MOIST® With LACREON® TECHNOLOGY
This study is an observational registry of patients who have recently been prescribed 1•DAY ACUVUE® TruEye® or 1•DAY ACUVUE® MOIST® Brand Contact Lenses with LACREON® TECHNOLOGY.
- Trial name
- TEMPO (NCT01467557)
- Testing
- narafilcon B daily disposable soft contact lenses, etafilcon A daily disposable soft contact lenses
- Where
- 37 sites in United States
- Volunteers
- 1,171 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Post-Market Clinical Survey of Clareon® IOL AutonoMe™ in Japanese Subjects
This purpose of this survey study is to collect and describe clinical outcomes for the intraocular lens (IOL) delivery performance of Clareon® IOL AutonoMe™ when used in daily practice.
- Trial name
- NCT03824028
- Testing
- Clareon® IOL AutonoMe™ automated preloaded delivery system
- Where
- 3 sites in Japan
- Volunteers
- 384 people
- Sponsor
- Alcon Research
Astigmatism
Orientation Characteristics of Daily Disposable Toric Contact Lenses
Brief summary: Approximately 30 soft toric contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double-masked (subject and investigator), repeated measures insertion study.
- Trial name
- NCT06069609
- Testing
- kalifilcon A Daily Disposable Toric, Acuvue Oasys 1-Day for Astigmatism
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Contact Lens Discomfort, Contact Lens-induced Corneal Disorder
Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel
This study compares contact lens comfortable wear duration, and signs and symptoms of contact lens discomfort, test versus control.
- Conditions
- Contact Lens Discomfort, Contact Lens-induced Corneal Disorder, Contact Lens Acute Red Eye, Contact Lens-induced Corneal Fluorescein Staining
- Trial name
- NCT03994406
- Testing
- CLM2 topical gel
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Glia, LLC
Cataract
Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing
This study compares two intraocular lenses, the Softec HD and the Tecnis Z9002, used to replace the natural crystalline lens after cataract extraction.
- Trial name
- NCT01249144
- Testing
- Intraocular Lens (IOL)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lenstec Incorporated
Myopia
Acute Clinical Evaluation of Multi-purpose Solutions (MPS) in Soft Contact Lens Wearers
The purpose of this study was to clinically evaluate lens care solutions used with soft contact lenses.
- Trial name
- NCT00929487
- Testing
- Contact lens multi-purpose solution, Saline/blister pack solution, Contact lenses
- Where
- United Kingdom
- Volunteers
- 278 people
- Sponsor
- Alcon Research
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
This study seeks to evaluate the impact of wearing a new daily disposable soft contact lens on the neophyte population.
- Trial name
- NCT00708032
- Testing
- spectacles, narafilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors
Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses
The purpose of this study is to assess long term performance and safety of verofilcon A soft contact lenses in a real-world setting in a population of 7 years or older having at least 1 year of verofilcon A (sphere or toric)…
- Trial name
- NCT06462456
- Testing
- Verofilcon A spherical soft contact lenses, Verofilcon A toric soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- Alcon Research
Myopia
BIOCLEAN MPS (Multi-Purpose Solution) VII in Combination With Biofinity Lens: A Two Week Crossover Study
Two week, Open Label, randomized, bilateral, crossover, 1 week of daily wear in each combination (lens / disinfecting cleaning system).
- Trial name
- NCT02537730
- Testing
- Bioclean MPS VII, Aosept Clearcare, comfilcon A
- Where
- 3 sites in Japan
- Volunteers
- 33 people
- Sponsor
- CooperVision, Inc.
Primary Open Angle Glaucoma (POAG)
Safety and Performance Study of the ARGOS-IO (Intraocular) System in Patients With Primary Open Angle Glaucoma (POAG)
The purpose of this study is to evaluate the safety and performance of the ARGOS-IO system in patients with POAG and indicated cataract surgery.
- Trial name
- NCT02434692
- Testing
- ARGOS-IO system
- Where
- 11 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Implandata Ophthalmic Products GmbH
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