Clinical trials: Lens Disease
Myopia
Acute Clinical Evaluation of Multi-purpose Solutions (MPS) in Soft Contact Lens Wearers
The purpose of this study was to clinically evaluate lens care solutions used with soft contact lenses.
- Trial name
- NCT00929487
- Testing
- Contact lens multi-purpose solution, Saline/blister pack solution, Contact lenses
- Where
- United Kingdom
- Volunteers
- 278 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Prospective Study of an Investigational Toric Soft Contact Lens
The purpose of this study was to demonstrate substantial equivalence of an investigational toric soft contact lens to the commercially available Focus® DAILIES® Toric soft contact lens when worn in a daily wear, daily disposable…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01461811
- Testing
- Nelfilcon A toric contact lenses (with comfort additives), Nelfilcon A toric contact lenses
- Volunteers
- 154 people
- Sponsor
- CIBA VISION
Aphakia, Cataract
Clinical Evaluation of a Novel Trifocal IOL
The purpose of this study is to understand the visual outcomes of the investigational intraocular lens (IOL) Model LPYWT0 when compared to the commercially marketed Clareon PanOptix Pro IOL Model PXYWT0.
- Trial name
- NCT07587138
- Testing
- LPYWT0, PXYWT0, Cataract Surgery
- Where
- 5 sites in Australia, India and 1 more
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Cataract, Corneal Astigmatism
Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism
The objectives of the clinical investigation are to determine the safety and performance of the RayOne EMV Toric (Model RAO210T) following unilateral implantation and approximately 6 months (120 to 180 days) of post-operative…
- Trial name
- NCT05985304
- Testing
- RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
- Where
- 9 sites in United States
- Volunteers
- 274 people
- Sponsor
- Rayner Intraocular Lenses Limited
Myopia
A Comparison of AIR OPTIX® COLORS Versus FRESHLOOK® COLORBLENDS
The purpose of this study was to evaluate the overall comfort of AIR OPTIX® COLORS compared to FRESHLOOK® COLORBLENDS in habitual wearers of the FRESHLOOK® COLORBLENDS .
- Trial name
- NCT01635933
- Testing
- Lotrafilcon B contact lens with color, Phemfilcon A contact lens with color
- Volunteers
- 370 people
- Sponsor
- Alcon Research
Myopia
Soft Lens Study: Biomedics 1 Day Extra Sphere and Clariti 1 Day Sphere
The aim of this study is to evaluate and compare the performance of two soft contact lenses.
- Trial name
- NCT06817785
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Cataract
Clinical Outcomes After Implantation of a Monofocal Hydrophobic IOL, Bi-Flex 877PAY With POB-MA Preloaded Injector
The purpose of our investigation is to retrospectively assess visual outcomes, refractive stability, safety features of the lens and the incidence of developing PCO (posterior capsular opacification) in a 12-month period…
- Trial name
- NCT06469541
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Medicontur Medical Engineering Ltd
Presbyopia
Comparison of Two Multifocal Contact Lenses
The purpose of this study is to compare two multifocal contact lenses in presbyopic wearers.
- Trial name
- NCT01250054
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 17 people
- Sponsor
- CIBA VISION
Myopia
Assessing the Performance of Lotrafilcon A Lenses During a Three Month Period
The purpose of this trial is to assess the performance of an investigational contact lens over a three month period.
- Trial name
- NCT00933166
- Testing
- Lotrafilcon A contact lens
- Volunteers
- 169 people
- Sponsor
- CIBA VISION
Cataract
A Clinical Investigation of MINIVISC® PLUS 14 mg/ml Fermented Ophthalmic Viscosurgical Device (OVD-F), Used for Cataract Surgery and Implantation of Intraocular Lenses, Glaucoma Surgery, Anterior Segment Surgery and Corneal Transplantation (CGAC)
A clinical investigation to confirm the clinical safety and performance of OVD-F device MINIVISC® PLUS 1.4 % for cataract surgery and implantation of intraocular lenses, glaucoma surgery, anterior segment surgery and corneal…
- Trial name
- Minivisc01 (NCT07184437)
- Testing
- OVD-F device Minivisc®PLUS 14 mg/ml
- Where
- 6 sites in Belgium, Sweden
- Volunteers
- 134 people
- Sponsor
- Bohus Biotech AB
Myopia
Multi-Center Clinical Evaluation of Two Reusable Soft Contact Lenses
The purpose of this study is to compare the subjective performance of comfilcon A lens against samfilcon A lens after 4 weeks of reusable lens wear.
- Trial name
- NCT02542072
- Testing
- comfilcon A, samfilcon A
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 90 people
- Sponsor
- CooperVision, Inc.
Myopia
Safety and Efficacy of a Contact Lens for Daily Disposable Use
This study is to evaluate the safety and efficacy of a new hydrogel daily disposable contact lens compared to the Bausch + Lomb SofLens® daily disposable contact lens when worn by current soft contact lens wearers on a daily…
- Trial name
- NCT01365039
- Testing
- Test, daily disposable contact lens, SofLens daily disposable contact lens
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error
Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses (Study 2)
The purpose of this study is to compare the subjective performance of two daily disposable contact lenses with respect to comfort and handling.
- Trial name
- NCT01917162
- Testing
- Nelfilcon A contact lens, UltraFilcon B contact lens
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- Alcon Research
Cataract
A Clinical Investigation of the ClarVista HARMONI™ Modular Intraocular Lens Implant Following Cataract Surgery
The main objectives of this feasibility study were: To demonstrate the feasibility of HARMONI Modular Intraocular Lens (HMIOL) implantation and assembly in subjects undergoing cataract surgery (All HMIOL Cohort), and To…
- Trial name
- NCT02521766
- Testing
- Harmoni Modular Intraocular Lens, Commercially Available Intraocular Lens, Optic exchange
- Where
- 2 sites in New Zealand, Philippines
- Volunteers
- 217 people
- Sponsor
- ClarVista Medical
Ametropia
Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens
The primary objective of thes study is to confirm that the ocular response to the Test lenses are similar to those of the Control lenses when used in a 1 week planned replacement, daily wear modality over a 1-month period.
- Trial name
- NCT01706770
- Testing
- enfilcon A, galyfilcon A
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Prospective Study of an Investigational Daily Disposable Contact Lens
The purpose of this study is to evaluate the performance of an investigational daily disposable contact lens.
- Trial name
- NCT01295905
- Testing
- delefilcon A contact lens, narafilcon B contact lens
- Volunteers
- 90 people
- Sponsor
- CIBA VISION
Myopia
BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens
To determine if patients are unreactive to the lens care solution / Biofinity combination.
- Trial name
- NCT02196766
- Testing
- Bioclean First Care EX / comfilcon A, Aosept Clearcare / comfilcon A
- Where
- 3 sites in Japan
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Myopia
Evaluation of Delefilcon A Contact Lenses
The purpose of the study is to evaluate the lens fit characteristics of delefilcon A contact lenses with different base curves and diameters.
- Trial name
- NCT06884202
- Testing
- Delefilcon A contact lenses with different base curves and diameters, Delefilcon A contact lenses with standard base curves and diameters
- Where
- 16 sites in United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Cataract Extraction
Exploratory Study of OMS302 Injection in Subjects Undergoing Unilateral Cataract Extraction by Phacoemulsification.
This is an exploratory study to determine the safety and clinical benefit of OMS302 Injection in subjects undergoing Cataract Extraction with Lens Replacement (CELR) using a coaxial phacoemulsification process.
- Trial name
- NCT00721695
- Testing
- OMS302, OMS302-PE, Vehicle
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Omeros Corporation
Cataracts
A Real-World Registry to Investigate the Performance of LenSx® Laser in Chinese Patients
The purpose of this study is to investigate the performance of LenSx® Laser in femtosecond laser-assisted cataract surgery (FLACS) in real-world medical practice in Chinese patients.
- Trial name
- NCT02396719
- Testing
- LenSx® Laser
- Where
- China
- Volunteers
- 1,541 people
- Sponsor
- Alcon Research
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