Clinical trials: Lens Disease
Cataract
Postmarket Study of an Intraocular Lens Power Selection System
The purpose of the study was to evaluate the visual acuity outcomes when using the Optiwave Refractive Analysis (ORA) with VerifEye+ and Barrett Toric Calculator for calculating intraocular lens (IOL) power and axis in subjects…
- Trial name
- NCT03579433
- Testing
- ORA with VerifEye+, Alcon Barrett Toric Calculator, Acrysof® IQ Toric IOL
- Where
- 9 sites in United States
- Volunteers
- 124 people
- Sponsor
- Alcon Research
Cataract
NPI-002 Intravitreal Implant for the Delay of Cataract Progression
This study will examine the safety and efficacy NPI-002 intravitreal implants post vitrectomy.
- Trial name
- NCT05026632
- Testing
- NPI-002 Intravitreal Implant
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Nacuity Pharmaceuticals, Inc.
Myopia, Moderate, Myopic Astigmatism
A Prospective, Randomized Clinical Study of Two Phakic Toric Implantable Lenses
Primary Objective: To compare the efficacy and the residual refractive error of EYECRYLTM Phakic toric versus Visian® Toric ICL in moderate to high myopic patient with co-existing astigmatism.
- Conditions
- Myopia, Moderate, Myopic Astigmatism, Myopia, Degenerative
- Trial name
- NCT06839898
- Testing
- EYECRYLTM Phakic Toric Intraocular Lens Treatment Arm, Visian® Toric ICL Treatment Arm
- Where
- 4 sites in Germany, India
- Volunteers
- 172 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Refractive Error, Myopia
Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan
The purpose of this study is to evaluate lens centration and subjective impressions of DAILIES® AquaComfort Plus® (DACP) lenses compared to 1-DAY ACUVUE® MOIST® (1DAM) lenses in ball sports players.
- Conditions
- Refractive Error, Myopia, Myopic Astigmatism
- Trial name
- NCT02103309
- Testing
- Nelfilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 42 people
- Sponsor
- Alcon Research
Refractive Error
Clinical Evaluation of MyDay™ and 1-DAY ACUVUE® TruEye®
The purpose of this study is to evaluate the functional vision of 2 daily disposable silicone hydrogel contact lenses using Time Controlled Visual Acuity (TCVA) measurements at high luminance and high contrast after 10+/-3 days…
- Trial name
- NCT02388763
- Testing
- Stenfilcon A contact lenses, Narafilcon A contact lenses
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Hyperopia, Myopia
A Clinical Comparison of Two Soft Contact Lenses (C24-755)
The aim of this study is to compare the short-term clinical performance of two soft contact lenses.
- Trial name
- NCT06758076
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 52 people
- Sponsor
- CooperVision, Inc.
Refractive Errors
Clinical Performance Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens
The purpose of this study is to obtain on-eye performance data to inform contact lens product development.
- Trial name
- NCT04055519
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, Multi-purpose disinfection solution
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Myopia
Evaluation of Daytime Corneal Swelling During Wear of Galyfilcon A Lenses
The purpose of this study is to evaluate corneal swelling, limbal redness, and endothelial bleb response to wearing galyfilcon A lenses in asian eyes.
- Trial name
- NCT01482819
- Testing
- galyfilcon A, galyfilcon A plus, lotrafilcon A
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia, Astigmatism
Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix
The purpose of this Post-Market Clinical Follow-up study is to describe the long-term safety and performance of the Clareon Vivity and Vivity Toric and Clareon PanOptix and PanOptix Toric IOLs.
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT05796453
- Testing
- Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 470 people
- Sponsor
- Alcon Research
Refractive Error
Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens
Randomized, double-masked, controlled, 2-arm parallel group, multi-site, 3-month dispensing study of Johnson \& Johnson Vision Care, Inc.
- Trial name
- NCT02515994
- Testing
- senofilcon C, comfilcon A
- Where
- 10 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Myopia
Presbyopic Phakic Intraocular Lens for Myopia Correction
This is a prospective single-center study of implantations of the presbyopic version of phakic intraocular lens IPCL (EyeolUK, United Kingdom).
- Trial name
- NCT03836898
- Testing
- Presbyopic posterior chamber phakic intraocular lens IPCL
- Where
- Czechia
- Volunteers
- 10 people
- Sponsor
- Gemini Eye Clinic
Refractive Errors, Ametropia
Clinical Performance of Two Commercial, Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of DAILIES TOTAL1 ( DT1) contact lenses with Infuse contact lenses.
- Conditions
- Refractive Errors, Ametropia, Myopia
- Trial name
- NCT05010512
- Testing
- Delefilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers
The purpose of this trial is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of 5 different daily disposable contact lenses.
- Trial name
- NCT00953407
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 128 people
- Sponsor
- CIBA VISION
Refractive Errors, Ametropia
Clinical Biocompatibility Evaluation of Contact Lens Coatings
The primary objective is to evaluate corneal staining observed after 2 hours of wear with contact lenses with investigational coating against PureVision™ lenses, all pre-cycled with OPTI-FREE® RepleniSH® multi-purpose…
- Trial name
- NCT03034928
- Testing
- Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Astigmatism
Comparison of Comfilcon A Toric Contact Lenses and Samfilcon A Toric Contact Lenses
The objective of this study is to evaluate the subjective acceptance of comfilcon A toric contact lens, compared to samfilcon A toric lens.
- Trial name
- NCT03519932
- Testing
- comfilcon A toric lens, samfilcon A toric lens
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- CooperVision, Inc.
Cataract
Retrospective Analysis of the Time Elements for Different Workflow Scenarios During Femtosecond Laser-assisted Cataract Surgery (FLACS) From the Surgeon, Staff, and Patient Perspectives.
This study involves the retrospecitve review of time stamps during surgery to assess the time efficiencies of different workflow scenarios of femtosecond laser-assisted cataract surgery from the surgeon, staff, and patient…
- Trial name
- NCT07038395
- Testing
- workflow
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- LensAR Incorporated
Dry Eye
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Assess the impact of concomitant Miebo use while wearing contact lenses
- Trial name
- NCT07054606
- Testing
- Perfluorohexyloctane ophthalmic solution
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Astigmatism
Observational Prospective Clinical Investigation on Monofocal Toric Intraocular Lens
Evaluation, at least one-year long-term, of the clinical performance and safety of Mini Toric Ready Intraocular Lens (IOL), a monofocal toric intraocular lens.
- Trial name
- NCT06250855
- Testing
- Mini Toric IOL
- Where
- 2 sites in Romania
- Volunteers
- 105 people
- Sponsor
- SIFI SpA
Cataract
Evaluation of 3 Intraocular Lenses Following Lens Extraction
The objective of this study is to evaluate the efficacy and subject satisfaction with three different FDA approved lenses for adults over 40 years of age who desire a reduction in spectacle dependence.
- Trial name
- NCT01122576
- Testing
- Crystalens AO, ReSTOR, Tecnis Multifocal IOL
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Clinical Investigation of the Bacterially-Derived Healon5 Ophthalmic Viscosurgical Device (OVD)
Prospective, multicenter, paired-eye, randomized, masked, clinical trial of the bacterially-derived Healon5 OVD versus the currently available Healon5 OVD control.
- Trial name
- NCT02782676
- Testing
- Investigational Healon5 OVD, Healon5 OVD
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
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