Clinical trials: Lens Disease
Myopia
1 Week Crossover Study Between Two Soft Contact Lenses
The objective of this investigation is to compare the visual clinical performance of two daily disposable soft contact lenses.
- Trial name
- NCT06611410
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Myopia, Refractive Errors
Clinical Comparison of Two Daily Disposable Soft Contact Lenses
The purpose of this study is to evaluate the overall performance of investigational contact lenses (DD T2) when compared to clariti® 1 day contact lenses.
- Trial name
- NCT03518008
- Testing
- verofilcon A contact lenses, somofilcon A contact lenses
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Alcon Research
Cataracts
Clinical Investigation of AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0]
The purpose of this study is to compare the safety and efficacy of an investigational multifocal intraocular lens (IOL) to an FDA-approved monofocal IOL.
- Trial name
- NCT01510717
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ Monofocal IOL Model SN60WF
- Volunteers
- 409 people
- Sponsor
- Alcon Research
Myopia
Performance Comparison Between Fanfilcon A and Senofilcon A Sphere Lenses
Prospective, multi-center, bilateral, double-masked, randomized, cross-over, daily wear, 1 month dispensing study (2 weeks each lens pair)
- Trial name
- NCT02956460
- Testing
- fanfilcon A, senofilcon A
- Where
- 4 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism
Clinical Evaluation of Invigor Toric 1-Day Contact Lenses
An evaluation of the clinical performance of the 1-day toric test contact lens compared to the 1-day toric control contact lens over one hour of lens wear.
- Trial name
- NCT04016623
- Testing
- 1-day toric test contact lens, 1-day toric control contact lens
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Astigmatism
Evaluate the Safety and Effectiveness of the Biotrue ONEday for Astigmatism
Comparing Test Lens for Astigmatism Soft Contact Lens (Test) to 1-Day Control for Astigmatism contact lenses (Control).
- Trial name
- NCT03681808
- Testing
- Control, Test
- Where
- 13 sites in United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
A Contralateral Dispensing Clinical Trial of Study Test Silicone Hydrogel Lens Against Enfilcon A Silicone Hydrogel Lens
This will be a 1-month dispensing, double-masked, randomized, contralateral study comparing the test lens against the control lens. The assignment of lenses to eyes (i.e.
- Trial name
- NCT02537717
- Testing
- Sapphire Lens, enfilcon A
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataracts
A Real-World Study in China for the TECNIS Eyhance™ Intraocular Lens
This is a prospective and retrospective, single-center, single-arm, open-label clinical study of the TECNIS Eyhance™ IOL. The study will enroll up to 100 subjects from a single site in China.
- Trial name
- NCT05090813
- Testing
- Model ICB00
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Presbyopia
Performance of a Multifocal Contact Lens - Presbyopia Study
This is a four week study to evaluate the performance of a multifocal contact lens in habitual wearers of silicone hydrogel multifocal contact lenses.
- Trial name
- NCT02450747
- Testing
- etafilcon A MULTIFOCAL
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Daily Disposable Silicone Hydrogel Contact Lens, Stenfilcon A, Clinical Study
Clinical evaluation of stenfilcon A compared with narafilcon A and delefilcon A This is a total 120 subject, randomized, open label, bilateral wear, two week crossover study (each lens for 1 week) evaluating the clinical…
- Trial name
- NCT02637804
- Testing
- stenfilcon A, narafilcon A, delefilcon A
- Volunteers
- 106 people
- Sponsor
- CooperVision, Inc.
Myopia
Adaptation To and Satisfaction With Contact Lens Wear In Myopic Young Adults
The purpose of this study was to assess whether young adults could adapt to and achieve satisfaction with a daily disposable contact lens.
- Trial name
- NCT04857723
- Testing
- daily disposable contact lens
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
A new multi-purpose solution (MPS)was clinically evaluated against Opti-Free RepleniSH MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01024855
- Testing
- RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Presbyopia
Clinical Evaluation of Two Multifocal Contact Lenses
The aim of this study is to evaluate the patient subjective experiences of the monthly multifocal lens when compared to the daily disposable multifocal lens after 15 minutes of daily wear.
- Trial name
- NCT05457608
- Testing
- Lens A, Lens B
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract
Clinical Trial to Evaluate the Model SC9 IOL Compared to the Model LI61SE IOL (Bausch & Lomb)
To evaluate the Model SC9 Intraocular Lens for the improvement of near and intermediate vision when compared to a legally marketed monofocal IOL.
- Trial name
- NCT03179397
- Testing
- Model SC9, Model LI61SE
- Where
- 13 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- CORD, LLC
Aphakia
Feasibility Study of an Accommodating IOL Design
The purpose of this clinical study is to assess safety and explore usability and effectiveness of the test product, AAL-FAIOL. This study will be conducted in Central America.
- Trial name
- NCT07147192
- Testing
- AAL-FAIOL, BAL-FAIOL, Phacoemulsification
- Where
- 4 sites in Costa Rica, Dominican Republic and 2 more
- Volunteers
- 17 people
- Sponsor
- Alcon Research
Myopia, Moderate, Myopic Astigmatism
A Prospective, Randomized Clinical Study of Two Phakic Toric Implantable Lenses
Primary Objective: To compare the efficacy and the residual refractive error of EYECRYLTM Phakic toric versus Visian® Toric ICL in moderate to high myopic patient with co-existing astigmatism.
- Conditions
- Myopia, Moderate, Myopic Astigmatism, Myopia, Degenerative
- Trial name
- NCT06839898
- Testing
- EYECRYLTM Phakic Toric Intraocular Lens Treatment Arm, Visian® Toric ICL Treatment Arm
- Where
- 4 sites in Germany, India
- Volunteers
- 172 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Cataract
Clinical Investigation of OMEGA Gemini Capsule, Model Gemini IV With an Approved Monofocal or Toric IOL
This study is a prospective, randomized, controlled, paired eye, subject-masked design.
- Trial name
- NCT04058314
- Testing
- Gemini IV, Control Eye
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Myopia
Clinical Comparison of Two Daily Disposable Contact Lenses in a Population of Daily Disposable Contact Lens Wearers
The purpose of this study is to evaluate the performance of two commercially marketed daily disposable contact lenses in a population of daily disposable contact lens wearers.
- Trial name
- NCT01233076
- Testing
- Nelfilcon A contact lens, Narafilcon B contact lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
Evaluation of the Performance of Monthly Replacement Sphere Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study is to evaluate the clinical performance of two monthly silicone hydrogel contact lenses in habitual wearers of frequent replacement (FRP) lenses when worn for one month.
- Trial name
- NCT05114564
- Testing
- Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
- Where
- 4 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract
Ocular Biodistribution Study for Topically Applied ESBA105
The purpose of this study is to determine whether ESBA105, a single-chain (scFv) antibody against TNF-alpha, efficiently penetrates into the anterior chamber and the vitreous body upon topical administration to the eye.
- Trial name
- NCT00820014
- Where
- 2 sites in Switzerland
- Volunteers
- 79 people
- Sponsor
- ESBATech AG
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