Clinical trials: Lens Disease
Aphakia, Presbyopia
Evaluation of AcrySof IQ Vivity Extended Vision Intraocular Lenses
The purpose of this post-market study is to describe the long-term safety and performance of AcrySof IQ Vivity and AcrySof IQ Vivity Toric intraocular lens (IOL) models in a real-world setting through routine clinical practice.
- Conditions
- Aphakia, Presbyopia, Residual Refractive Cylinder
- Trial name
- NCT06541795
- Testing
- AcrySof IQ Vivity Extended Vision IOL
- Where
- United States
- Sponsor
- Alcon Research
Cataract, Refractive Error
A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL
This is a multicenter, prospective, randomized, subject- and evaluator-masked, bilateral-implant study conducted at up to 15 sites worldwide.
- Trial name
- NCT04156737
- Testing
- TECNIS Symfony plus IOL Model ZHR00V, Trifocal Intraocular lens
- Where
- 5 sites in New Zealand, Philippines and 1 more
- Volunteers
- 205 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Surgeon Experience ReSTOR A +4 Intraocular Lens (IOL)
To collect visual outcome data post AcrySof ReSTOR Aspheric +4 implantation from surgeons throughout the United States.
- Trial name
- NCT00733512
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Alcon Research
Presbyopia
Multifocal High ADD Contact Lens Proof of Concept Trial
The purpose of this study is to evaluate the visual performance of a new multifocal High ADD contact lens compared to the currently-marketed AIR OPTIX® AQUA MULTIFOCAL (AOAMF) High ADD Contact Lens.
- Trial name
- NCT02117544
- Testing
- Lotrafilcon B multifocal contact lenses (new), Lotrafilcon B multifocal contact lenses
- Volunteers
- 268 people
- Sponsor
- Alcon Research
Inflammation, Cataract
Study of Dexycu in Treating Intraocular Inflammation
This is a phase III, prospective, randomised, double-masked, placebo-controlled, parallel-design, multicenter study of the efficacy, safety and pharmacokinetics of 9% dexamethasone intraocular injection for the treatment of…
- Trial name
- NCT06429306
- Testing
- Dexycu
- Where
- China
- Volunteers
- 285 people
- Sponsor
- Ocumension Therapeutics (Shanghai) Co., Ltd
Open-Angle Glaucoma
A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Glaucoma
The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with open-angle glaucoma or ocular hypertension and co-existing…
- Trial name
- NCT00323284
- Testing
- iStent plus Cataract Surgery, Cataract surgery only
- Where
- 31 sites in United States
- Volunteers
- 240 people
- Sponsor
- Glaukos Corporation
Cataract
Visual Outcomes After Cataract Surgery: Multifocal AcrySof® IQ ReSTOR® Intraocular Lenses Versus Monofocal Intraocular Lenses
The purpose of this study is to assess and compare visual outcomes of the AcrySof® IQ ReSTOR® +3.0 D intraocular lens (IOL) to a commercially available monofocal IOL in cataract patients.
- Trial name
- NCT01290068
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL, Monofocal IOL
- Volunteers
- 208 people
- Sponsor
- Alcon Research
Cataract, Corneal Astigmatism
Clinical Investigation of the Safety and Effectiveness of an Investigational Model of the TECNIS® Intraocular Lens
This study will be a prospective, multicenter, bilateral, comparative, three-way masked (Sponsor, subject and evaluator), randomized clinical investigation conducted at up to 15 sites.
- Trial name
- BRAVO (NCT03949335)
- Testing
- IOL Model ZFR00V, IOL Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 272 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Ametropia
Ocular Responses to Short and Long-term Lens Wear
The purpose of this study was to determine whether ocular surface sensitivity to pneumatic, mechanical and chemical stimulation would be affected by the use of the combination of a specific silicone hydrogel lens material with…
- Trial name
- NCT00722891
- Testing
- Purevision Lenses with ReNu Multiplus, Purevision Lenses with Optifree RepleniSH
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Assessment of Low Energy Lens Fragmentation Cataract Extraction in Patients Undergoing Cataract Surgery
The purpose of this research study is to evaluate the clinical outcomes of the use of low-energy segment removal with a micro-interventional irrigation/aspiration port (MICOR-304) to evacuate the lens prior to intraocular lens…
- Trial name
- NCT04747834
- Testing
- MICOR-304
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Myopia
Comparative Study of the Wearing Satisfaction of Two Soft Contact Lens Designs.
To evaluate the wearing satisfaction of a new design of the PureVision soft contact lenses.
- Trial name
- NCT00768885
- Testing
- PureVision 1, PureVision 2
- Where
- Japan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataracts
Cataract Surgery in Indian Patients With or Without LenSx® Laser
The purpose of this study is to record and analyze the profile and outcome of cataract patients receiving phacoemulsification (phaco) and artificial intraocular lens (IOL) implantation with or without femtosecond laser-assisted…
- Trial name
- NCT02605408
- Testing
- LenSx® laser system, Phacoemulsification
- Sponsor
- Alcon Research
Astigmatism
A Clinical Comparison of Two Soft Toric Contact Lenses
The aim of this study is to compare the short-term clinical performance of two toric contact lenses.
- Trial name
- NCT06758089
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia Correction, Astigmatism
A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery
To evaluate the clinical outcomes and patient satisfaction of two commercially available trifocal toric intraocular lenses Primary Objective: To compare the distance-corrected intermediate visual acuity between the two trifocal…
- Conditions
- Presbyopia Correction, Astigmatism, Cataract
- Trial name
- NCT07232615
- Testing
- Optiflex TRIO Intraocular Lens, AcrySof® IQ PanOptix®
- Where
- 6 sites in Germany, India and 1 more
- Volunteers
- 138 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Refractive Errors
Prospective Study of the Health Benefits of Ultra-Violet Filtering Contact Lenses
The purpose of this study is to examine the short-term protective effect of Ultra-Violet filtering contact lenses on macular pigment ocular density.
- Trial name
- NCT01444313
- Testing
- narafilcon A contact lens, nelfilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia, Astigmatism
Clareon IOL Retrospective Data Collection
The purpose of this study is to provide real world evidence (RWE) on the performance of the Clareon ultraviolet absorbing (UVA) intraocular lenses (IOLs) to support the overall body of evidence on the Clareon IOL family.
- Trial name
- NCT05796674
- Testing
- Clareon UVA IOL, WaveTec Optiwave Refractive Analysis (ORA) System, Cataract surgery
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- Alcon Research
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to evaluate visual and refractive parameters in a series of subjects bilaterally implanted with presbyopia-correcting intraocular lenses (IOLs) during cataract surgery.
- Trial name
- NCT01257217
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL Model SND1TT, Acri.LISA® 366D IOL
- Volunteers
- 31 people
- Sponsor
- Alcon Research
Refractive Error
Tear Film Stability of DAILIES® AquaComfort Plus® Contact Lenses vs. MyDay® Daily Disposable Contact Lenses
The purpose of this study is to evaluate tear film stability of DAILIES® AquaComfort Plus® (DACP) compared to MyDay® after 12 hours of lens wear.
- Trial name
- NCT02089191
- Testing
- Nelfilcon A contact lenses, Stenfilcon A contact lenses
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Alcon Research
Cataract, Pseudophakia
Retrospective, Non-interventional Clinical Investigation of the Safety and Performance of 640AD Monofocal Intraocular Lens
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOL) is indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Trial name
- NCT06578910
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- Hungary
- Volunteers
- 80 people
- Sponsor
- Medicontur Medical Engineering Ltd
Myopia, Hyperopia
DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study
The purpose of this study is to continuously assess the visual performance and safety of DAILIES TOTAL1 soft contact lenses in a real world setting and broader patient base through routine clinical practices.
- Conditions
- Myopia, Hyperopia, Presbyopia, Astigmatism
- Trial name
- NCT06483113
- Testing
- Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 192 people
- Sponsor
- Alcon Research
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.