Clinical trials: Lens Disease
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Cataract
Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery
The purpose of this study is to demonstrate the non-inferiority of the study treatment (combined levofloxacin + dexamethasone eye drops) followed by dexamethasone eye drops alone vs.
- Trial name
- LEADER7 (NCT03739528)
- Testing
- Levofloxacin + dexamethasone followed by dexamethasone, Tobramycin + Dexamethasone
- Where
- 57 sites in Italy
- Volunteers
- 808 people
- Sponsor
- NTC srl
Intraocular Lens Replacement
Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
The purpose of this study is to determine the safety, efficacy and pharmacokinetics of OMS302 (the study drug) for maintaining intraoperative mydriasis and preventing post operative pain in individuals undergoing Intraocular Lens…
- Trial name
- OMS302-ILR-004 (NCT01579565)
- Testing
- OMS302
- Where
- 14 sites in United States, Netherlands
- Volunteers
- 416 people
- Sponsor
- Omeros Corporation
Myopia
Evaluation of The Clinical Acceptance of Soft Contact Lenses for Myopia Control
The main objective of the study was to evaluate the clinical acceptance of soft contact lenses for Myopia control.
- Trial name
- NCT04709237
- Testing
- omafilcon A control lens, omafilcon A test lens 1, omafilcon A test lens 2
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error
AIR OPTIX® COLORS Registration Trial
The purpose of this study was to evaluate the subjective and objective performance and the physiological response to AIR OPTIX® COLORS soft contact lenses compared with AIR OPTIX® AQUA contact lenses in participants with normal…
- Trial name
- NCT01440322
- Testing
- Lotrafilcon B contact lens with color, Lotrafilcon B contact lens
- Volunteers
- 150 people
- Sponsor
- CIBA VISION
Myopia
Multi-Center Clinical Evaluation of Two Reusable Soft Contact Lenses
The purpose of this study is to compare the subjective performance of comfilcon A lens against samfilcon A lens after 4 weeks of reusable lens wear.
- Trial name
- NCT02542072
- Testing
- comfilcon A, samfilcon A
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 90 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Myopia
Evaluation of Delefilcon A Contact Lenses
The purpose of the study is to evaluate the lens fit characteristics of delefilcon A contact lenses with different base curves and diameters.
- Trial name
- NCT06884202
- Testing
- Delefilcon A contact lenses with different base curves and diameters, Delefilcon A contact lenses with standard base curves and diameters
- Where
- 16 sites in United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Aphakia, Cataract
Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT03895034
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- RxSight, Inc.
Aphakia, Cataract
Single Center Exploratory Study To Evaluate The Use Of The RxSight Light Adjustable Lens (LAL) And The Light Delivery Device (LDD) To Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT04529616
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 79 people
- Sponsor
- RxSight, Inc.
Refractive Error
Clinical Performance of a Silicone Hydrogel for Daily Disposable Wear
The purpose of this study is to compare the visual acuity of an investigational silicone hydrogel to a commercially available silicone hydrogel in contact lens wearers.
- Trial name
- NCT03095027
- Testing
- FID122819 contact lenses, Stenfilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Refractive Error
Tear Film Evaluation of Dailies® AquaComfort Plus® Multifocal and Toric
The purpose of this study is to evaluate the pre lens tear film characteristics of DAILIES® Aqua Comfort Plus® Multifocal (DACP MF) and Toric (DACP Toric) compared to DAILIES® Aqua Comfort Plus® Sphere (DACP) daily disposable…
- Trial name
- NCT02289742
- Testing
- Nelfilcon A multifocal contact lenses, Nelfilcon A toric contact lenses, Nelfilcon A sphere contact lenses
- Volunteers
- 48 people
- Sponsor
- Alcon Research
Cataract, Inflammation
Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
The objective of this clinical study is to compare the safety and efficacy of mapracorat ophthalmic suspension, 3% with its vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Conditions
- Cataract, Inflammation, Surgery
- Trial name
- NCT01591655
- Testing
- Mapracorat, Vehicle
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Multi-Centre Clinical Evaluation Of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the subjective performance for handling of two daily disposable contact lenses, stenfilcon A and etafilcon A.
- Trial name
- NCT01707238
- Testing
- etafilcon A, stenfilcon A
- Where
- 7 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- CooperVision, Inc.
Visual Disorder
A Clinical Trial to Evaluate Investigational Silicone Hydrogel Contact Lenses Worn Continuously for One Week
This study is a prospective, randomized, double-masked, bilateral, dispensing, parallel-group clinical trial design. All subjects will participate in a 2-week daily disposable contact lens adaptation period prior to being…
- Trial name
- NCT02543528
- Testing
- Investigational Lens 1, Investigational Lens 2, Investigational Lens 3
- Where
- India
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Ocular Comfort and the "Aging" Lens (ERBIUM)
The purpose of this trial was to evaluate the factors affecting comfortable contact lens wear and how those factors affect contact lens replacement frequency.
- Trial name
- NCT01198600
- Testing
- Habitual contact lens, Lotrafilcon B contact lens, Contact lens cleaning and disinfecting system (ClearCare)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- CIBA VISION
Primary Open Angle Glaucoma, Cataract
Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent
The purpose of this study is to assess long-term (10 years post-CyPass implantation) status of the corneal endothelium in subjects who were implanted with the CyPass Micro-Stent in the COMPASS trial.
- Trial name
- COMPASS XXT (NCT04629521)
- Testing
- CyPass Micro-Stent, Cataract Surgery
- Where
- 12 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Ametropia
Evaluation of Investigational (Frequent Replacement) FRP Lens for Daily Wear
The purpose of the study is to compare the investigational contact lens to a marketed contact lens. The study results were not used for design validation of investigational contact lens,
- Trial name
- NCT02362724
- Testing
- Sapphire, Pearl
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Performance of Existing Wearers of Enfilcon A Following a Refit With Fanfilcon A Lenses for 4 Weeks
The aim of this dispensing study is to evaluate the clinical performance of habitual wearers of enfilcon A lenses following a refit with fanfilcon A lenses over 4 weeks of daily wear.
- Trial name
- NCT02670473
- Testing
- fanfilcon A (test)
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataracts
A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
The purpose of this study is to compare AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in both eyes (bilateral implantation) to AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in the dominant eye with AcrySof® IQ ReSTOR® +3.0 D Multifocal…
- Trial name
- NCT01684007
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Myopia, Presbyopia
Clinical Comparison of Two Multifocal Contact Lenses Made of Silicone Hydrogel Materials
The purpose of this study was to compare visual performance measures between two multifocal contact lenses on presbyopic wearers.
- Trial name
- NCT01371539
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 109 people
- Sponsor
- CIBA VISION