Clinical trials: Lens Disease
Retinal Detachment, Macular Pucker
Zeiss RESIGHT Disposable Lenses Evaluation Study
To evaluate the intra-operative efficacy of a new intra-operative viewing device.
- Conditions
- Retinal Detachment, Macular Pucker, Macular Holes, Vitreomacular Traction
- Trial name
- RESIGHT (NCT05860985)
- Testing
- ZEISS disposable
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cataract Surgery, Cataract
Evaluation of Head-Mounted Spatial Computing and Three-Dimensional (3D) Visualization in Ocular Microsurgery: A Safety and Workflow Study
The purpose of this research is to evaluate the use of the research study device, the Apple Vision Pro head-mounted spatial computing display, with the Zeiss Artevo 850 digital microscope system, for the visualization during…
- Trial name
- NCT07301385
- Testing
- Apple Vision Pro (Head-Mounted Spatial Computing Display), Zeiss Artevo Digital Surgical Microscope
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Sharp HealthCare
Age-related Cataract
Metabo-lipidomics of the Ocular Surface for Cataract Surgery
Cataract is the world's leading cause of blindness, the treatment of which, exclusively surgical, offers excellent results in terms of visual recovery.
- Trial name
- CATARACTOMIQUE (NCT05802550)
- Testing
- Ocular Surface Disease Index, Interferometry, Oxford score
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Cataract
Postoperative Discomfort and Ocular Redness Following Phacoemulsification Surgery
Primary objective of the study is the assessment of the patients' discomfort and ocular redness following cataract extraction surgery by means of phacoemulsification and intraocular lens implantation.
- Trial name
- NCT02558218
- Testing
- Systane Ultra, tobradex quid (Standard)
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Democritus University of Thrace
Refractive Error
Initial Performance of a Modified Daily Disposable Contact Lens
The purpose of this study is to evaluate the incidence of ocular discomfort device-related adverse events with DAILIES TOTAL1® with UV Absorber (DT1 UV) contact lenses compared with current DAILIES TOTAL1® (DT1) contact lenses.
- Trial name
- NCT02694835
- Testing
- Delefilcon A contact lenses with UV Absorber, Delefilcon A contact lenses
- Volunteers
- 81 people
- Sponsor
- Alcon Research
Cataract
Evaluation of the Rotational Stability of the Monofocal SISA Implant Following Cataract Surgery
A good efficacy as well as good rotary stability is expected with the ocular implant.
- Trial name
- SISALens (NCT03356847)
- Testing
- Fitting of ocular implant
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cataract
Brillouin Scanning in Cataractous Eyes
To provide first results for biomechanical properties of cataractous lenses via Brillouin microscopy and correlations between LOCS III grading, cataractous lens scans from optical coherence tomography (OCT), and intraoperative…
- Trial name
- NCT07425626
- Testing
- Brillouin-Microscopy
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Fuchs' Endothelial Dystrophy, Cataract
Risk Assessment for Progression to DMEK Following Cataract Surgery in Fuchs Endothelial Corneal Dystrophy
Justification. Fuchs' corneal endothelial dystrophy (FECD) is one of the main causes of corneal transplantation. In many cases, the corneal decompensation derived from this dystrophy is triggered as a consequence of cataract…
- Trial name
- NCT04072029
- Testing
- Phacoemulsification with intraocular lens implantation
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Cataract
OCT-PRO Model vs. Clinicians: Cataract Surgery Outcome Prediction
Cataract is the leading cause of blindness worldwide, yet 5-20% of patients fail to achieve satisfactory visual recovery after surgery.
- Trial name
- NCT07713069
- Testing
- OCT-PRO prediction model, Routine Preoperative Counseling
- Volunteers
- 534 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Influence of an Capsular Tension Ring on the Rotation of an Intraocular Lens (Aspira®-aA Also Known as MC 6125 AS)
The purpose of this study is to observe the axial IOL rotation after surgery with a capsular tension ring (CTR) and a MC6125 AS IOL.
- Trial name
- NCT02649257
- Testing
- cataract surgery, intraocular lens (MC 6125 AS), capsular tension ring (CTR 13/11)
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Primary Open-angle Glaucoma, Cataract
Post Approval Study of the CyPass System
The purpose of this study is to demonstrate that the rate of clinically relevant complications associated with CyPass Micro-Stent placement and stability using the CyPass 241-S applier, as determined at 36 months in the…
- Trial name
- NCT03273907
- Testing
- CyPass Micro-Stent implanted with CyPass 241-S applier, Cataract surgery
- Where
- 20 sites in United States
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Fuchs' Corneal Dystrophy, Cataract
Combined Cataract Surgery and Planned Descemetorhexis
A pilot study designed to assess the feasibility of planned descemetorhexis for the treatment of Fuchs' corneal dystrophy.
- Trial name
- NCT02206594
- Testing
- Descemetorhexis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Medical College of Wisconsin
Presbyopia, Refractive Errors
Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses
Primary objective of this study is to compare two presbyopia correction surgical techniques, specificaly premium monovision, in which the dominant eye is corrected with an extended depth of field intraocular lens and the…
- Conditions
- Presbyopia, Refractive Errors, Cataract
- Trial name
- NCT05494177
- Testing
- bUDVA, bUIRA, bUNRA, bUICPS, bUNCPS, Contrast sensitivity
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Democritus University of Thrace
Astigmatism, Myopia
Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens Wearers
To compare the performance of two leading soft multifocal Toric contact lenses.
- Trial name
- NCT07829419
- Testing
- Lens A ( comfilcon A), Lens B ( lehfilcon A)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- CooperVision International Limited (CVIL)
Cataract, Intraocular Lens Complication
Functional IOL Implantation in Patients With Epiretinal Membrane
We have designed this prospective study to evaluate macular involvement and epiretinal membrane (ERM) grading by OCT in eyes with ERM and to compare clinical outcomes after implantation of Enhance IOL with standard monofocal IOL…
- Conditions
- Cataract, Intraocular Lens Complication, Epiretinal Membrane
- Trial name
- NCT06719739
- Testing
- Intraocular lens implantation
- Where
- 2 sites in China
- Volunteers
- 90 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Sjögren's Syndrome
MSCohi-O Lenses for Ocular Involvement in Sjögren's Syndrome
This study is aSingle-center, multiple-dosing, prospective, nonrandom, single-arm trial.
- Trial name
- NCT07185139
- Testing
- MSCohi-O Lenses
- Volunteers
- 12 people
- Sponsor
- Guangdong ProCapZoom Biosciences Co., Ltd.
Presbyopia, Cataract
The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.
- Trial name
- NCT00624039
- Testing
- UBM with pilocarpine in presbyopia
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Samsung Medical Center
Presbyopia
A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens
The objective of this study is to evaluate the product performance of an investigational multifocal low add soft contact lens.
- Trial name
- NCT01539694
- Testing
- LD118033 contact lens, PureVision multifocal contact lens
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Vitrectomy
Clinical Study to Confirm the Safety and Performance of the Virtuoso Phaco-vitrectomy Device
This is a pre-market clinical investigation with a device that does not bear the CE-marking. Aim of the study is to confirm the safety and performance of the device and collect user feedback.
- Conditions
- Cataract, Vitrectomy, Vitrectomy Operation Under General Anesthesia
- Trial name
- Virtuoso1 (NCT06799156)
- Where
- Germany
- Volunteers
- 205 people
- Sponsor
- Beaver-Visitec International, Inc.
Visual Disorder
Clinical Evaluation of Approved and Investigational Contact Lenses
This study is a multi-site, 5-visit dispensing, bilateral double-arm parallel group design, double-masked clinical trial using an investigational contact lens and a marketed contact lens.
- Trial name
- NCT02669095
- Testing
- Investigational Contact Lenses (Test), Marketed Contact Lenses (Control)
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
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