Clinical trials: Lens Disease
Refractive Error, Myopia
A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects
The purpose of this study is to compare the change from baseline in central corneal curvature at one week, between 2 silicone hydrogel lenses, in higher myopic subjects.
- Trial name
- NCT02066922
- Testing
- Delefilcon A contact lens, Narafilcon A contact lens, Spectacles
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
Evaluation of Toric Intraocular Lens(IOL) Combined With Capsular Tension Ring(CTR) in Patients With Cataract Combined With High Myopia
The objective of this study is to evaluate the postoperative visual quality and IOL stability in patients with cataracts and high myopia who have undergone surgery using astigmatism-correcting IOLs in conjunction with tension…
- Conditions
- Cataract, Astigmatism, Intraocular Lens Rotation
- Trial name
- NCT06571773
- Testing
- intraoperative implantation of Capsular Tension Ring, none intraoperative implantation of CTR
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai 10th People's Hospital
Myopia
Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study
This project aims to study the effects of treatment characteristics on myopia control in orthokeratology by investigating the effects of modified treatment zone by reducing the lens back optic zone diameter on the effect of…
- Trial name
- NCT03191942
- Testing
- Modified ortho-k lenses, Ortho-k lenses
- Where
- 2 sites in Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cataract, Pseudophakia
Clinical Outcomes of Patients Implanted With the RxSight Light Adjustable Lens (LAL)
The objective of this investigator initiated study (IIT-002) is to collect data on commercial patients implanted with the RxSight Light Adjustable Lens (LAL).
- Trial name
- NCT06488066
- Testing
- Data collection
- Where
- United States
- Sponsor
- Vance Thompson Vision
Cataract, Cataract Surgery
Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)
This study aims to generate data that characterizes visual outcomes, including the binocular distance-corrected intermediate visual acuity (DCIVA) at 66cm or defocus behavior, of the Clareon TruPlus modified monofocal intraocular…
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- BMVDI (NCT07589894)
- Testing
- Clareon TruPlus IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colvard Kandavel Eye Center
Cataract, Near Vision
The Best Way to Improve the Near Visual Acuity After ZXR00 IOL Implantation
The Best Way to Improve the Near Visual Acuity After ZXR00 IOL Implantation
- Trial name
- NCT05594537
- Volunteers
- 30 people
- Sponsor
- Yune Zhao
Astigmatism
Clinical Performance and Outcomes After Toric Lens Transition
To evaluate subjective and clinical outcomes after transitioning from one toric soft contact lens to another over a one-month period.
- Trial name
- NCT07898995
- Testing
- Fanfilcon A Toric Contact Lens
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision International Limited (CVIL)
Cataract, Presbyopia
IC-8 Apthera IOL New Enrollment Post Approval Study
The purpose of this study is to verify the post-market safety of the IC-8 Apthera IOL after the treatment of posterior capsular opacification (PCO), an expected complication related to IC-8 Apthera IOL implantation.
- Conditions
- Cataract, Presbyopia, Posterior Capsule Opacification
- Trial name
- NCT06060041
- Where
- 14 sites in United States
- Volunteers
- 435 people
- Sponsor
- Bausch & Lomb Incorporated
Cataracts
A Prospective Study Comparing Visual Outcomes and Patient Satisfaction Following Implantation of the Clareon PanOptix Versus Tecnis Odyssey IOL in Patients Undergoing Cataract Surgery.
To evaluate visual outcomes and patient satisfaction following bilateral implantation of the Clareon PanOptix versus Tecnis Odyssey IOL in patients undergoing cataract surgery
- Trial name
- NCT07768475
- Testing
- Intraocular Lens Implant
- Where
- 4 sites in United States
- Volunteers
- 266 people
- Sponsor
- Nvision Laser Eye Centers
Refractive Errors
Bifocal & Atropine in Myopia (BAM) Study
This study will test whether the combined treatment of 0.01% atropine and soft bifocal contact lens wear produces slower myopia progression and axial elongation compared to soft bifocal contact lenses alone in children ages 7 to…
- Trial name
- BAM (NCT03312257)
- Testing
- Multifocal D +2.50 add & 0.01% atropine
- Volunteers
- 49 people
- Sponsor
- Jenny Jones
Cataract
Pilot Study: Dynamic Light Scattering Device for Studying Early Changes in Cataract
This study will use a new dynamic light scattering device (DLS), developed jointly by NASA and the NEI, to study pre-senile cataracts (cataracts that develop in patients 55 years old or less).
- Trial name
- NCT00067483
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- National Eye Institute (NEI)
Cataract, Spherical Aberrations
Optical Quality After Implantation of a Spherical or Aspherical Intraocular Lens in Hypermetropic Patients
The purpose of this study is to evaluate differences in the depth of focus after implantation of a spherical or aspheric IOL in hypermetropic and emmetropic patients.
- Conditions
- Cataract, Spherical Aberrations, Intraocular Lenses, Depth of Focus
- Trial name
- NCT01995630
- Testing
- AMO Tecnis ZA9003, AMO Sensar AR40e
- Where
- Austria
- Volunteers
- 62 people
- Sponsor
- Medical University of Graz
Contact Lens Discomfort, Dry Eye Disease
Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers
The purpose of this prospective study is to evaluate the benefits of using the Bruder Moist Heat Compress in contact lens wearers who report reduced comfortable wear time.
- Conditions
- Contact Lens Discomfort, Dry Eye Disease, Meibomian Gland Dysfunction
- Trial name
- NCT02848222
- Testing
- Bruder Moist Heat Compress, Washcloth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Myopia
Wearing Behavior and Eye Length Changes in Children With Myopia Wearing Myopia Control Spectacle Lenses
The goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses…
- Trial name
- NCT07780851
- Testing
- Single Vision Lens (SVL), Myopia Control Lens (MCL)
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Ocular Surface Disease
Clinical Application Research of Scleral Lenses in Ocular Surface Diseases
To evaluate the therapeutic efficacy of scleral lenses in patients with irregular corneal astigmatism stemming from ocular surface diseases (OSD), focusing on visual acuity improvement, comfort, and overall satisfaction.
- Trial name
- NCT06555367
- Testing
- scleral lenses
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT02553681
- Testing
- roflufocon D contact lenses, RGP contact lenses made from roflufocon D
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Inflammation, Cataract
A Real-world Study of DEXYCU in the Treatment of Inflammation After Cataract Surgery
This is a prospective, real-world study aimed to evaluate the efficacy and safety of Dexycu in treating postoperative inflammation of cataracts.
- Trial name
- NCT06497699
- Testing
- Dexycu
- Where
- 2 sites in China
- Volunteers
- 263 people
- Sponsor
- Ocumension Therapeutics (Shanghai) Co., Ltd
Pain
Intravitreal Injection Site and Perceived Pain
The objective of this study is to explore the perception of pain during intravitreal injection related to the distance of the entry site from the limbus.
- Trial name
- NCT05640895
- Testing
- Intravitreal injection site
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Refractive Errors
Air Optix Extended Wear Contact Lenses
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term performance and safety of Air Optix Aqua Sphere, Air Optix plus HydraGlyde Sphere, and Air Optix plus HydraGlyde Toric soft contact lenses in…
- Trial name
- NCT05886881
- Testing
- Lotrafilcon B spherical soft contact lenses, Lotrafilcon B spherical soft contact lenses with comfort additive, Lotrafilcon B toric soft contact lenses with comfort additive
- Where
- 4 sites in United States
- Volunteers
- 505 people
- Sponsor
- Alcon Research
Cataract, Miosis
Nepafenac Versus Ketorolac Eye Drops in Prevention of Intraoperative Miosis During Cataract Surgery
This study aim at determining the efficacy of Nepafenac and Ketorolac in obtaining adequate intraoperative mydriasis and preventing miosis during cataract surgery.
- Trial name
- NCT03851172
- Testing
- Ketorolac Ophthalmic, Nepafenac Ophthalmic, Cyclopentolate Ophthalmic
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
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