Clinical trials: Lens Disease
Cataract
The Visual Plasticity During Adversity and Prosperity in Infants With Congenital Cataracts
Phenotypic plasticity is the ability of individuals to change their phenotypic status when exposed to environmental variations. However, whether the plastic changes show differential susceptibility in adversity and prosperity is…
- Trial name
- NCT03593824
- Testing
- bilateral cataract removal surgery for dense cataract, bilateral cataract removal surgery for non-dense nuclear cataract
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Intraoperative Floppy Iris Syndrome, Cataract
Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome (IFIS) is a potentially serious cataract surgery complication. IFIS is most commonly associated with the chronic use of tamsulosin and other alpha1-adrenergic receptor antagonists prescribed in…
- Conditions
- Intraoperative Floppy Iris Syndrome, Cataract, Age-related Cataract, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT06266962
- Testing
- 1% Atropine drops, Epinephrine
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- University Hospital Olomouc
Keratoconus
A Clinical Study of Keratoconus in Asian Patients and Assessment of Different Topographic Patterns of Keratoconus in Asian Patients
A clinical study of keratoconus in Asian Patients and assessment of different topographic patterns of keratoconus in Asian patients
- Trial name
- NCT00347074
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Cataract, Presbyopia
The Visual Performances of a Progressive Multifocal Intraocular Lens With Extended Depth of Focus
The purpose of this observational, non-controlled, multicenter trial with a retrospective design is to evaluate the visual performance of one cohort of patients who received the EDOF MINI WELL® intraocular lenses following…
- Trial name
- NCT02740010
- Testing
- EDOF Mini WELL Ready IOL
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- SIFI SpA
Cataract
Visual Performance of the Vivity IOL in Post-myopic LASIK and PRK Patients
The objective is to evaluate visual outcomes and patient satisfaction in patients with a history of myopic LASIK or PRK who will have completed cataract surgery with the Vivity IOL.
- Trial name
- NCT05961046
- Testing
- Vivity IOL
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Laser & Corneal Surgery Associates
Cataract
A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
The goal of this clinical trial is to learn if MELT-300 works on procedural sedation in adult participants undergoing cataract extraction with lens replacement (CELR). It will also learn about the safety of MELT-300.
- Trial name
- NCT06383273
- Testing
- MELT-300 sublingual tablet, Midalozam sublingual tablet
- Where
- 12 sites in United States
- Volunteers
- 528 people
- Sponsor
- Melt Pharmaceuticals
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION
Myopia
Performance Comparison Between Comfilcon A and Senofilcon C Lenses
The aim of this study is to determine the clinical performance of comfilcon A in comparison to senofilcon C.
- Trial name
- NCT02920957
- Testing
- comfilcon A, senofilcon C
- Where
- 5 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Aphakia
Clinical Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL)
The purpose of this study is to evaluate the safety and effectiveness of an investigational IOL.
- Trial name
- NCT02049567
- Testing
- FluidVision AIOL, Cataract Surgery
- Where
- 8 sites in Germany, South Africa
- Volunteers
- 170 people
- Sponsor
- PowerVision
Refractive Error
Formula Identification (FID) 114657 in Contact Lens Wearers
The purpose of this study is to evaluate the thickness of the pre-lens tear lipid layer after 2 hours of lens wear with use of FID 114657 compared to saline control.
- Trial name
- NCT02293538
- Testing
- FID 114657 eye drops (10 ml), Saline control eye drops (15 ml), Habitual contact lenses
- Volunteers
- 234 people
- Sponsor
- Alcon Research
Allergic Conjunctivitis
Use of BEPREVE (Bepotastine Besilate Ophthalmic Solution) 1.5% for Allergic Conjunctivitis and Contact Lenses
The purpose of this study is to assess if BEPREVE (bepotastine besilate ophthalmic solution) 1.5% will have an effect on contact lens wear in patients with contact lens intolerance due to allergic conjunctivitis.
- Trial name
- NCT01337557
- Testing
- Bepotastine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Glaucoma, Cataract Senile
Effect of Presbyopic Correction Lens on Humphrey Visual Field Testing in Patients With Multifocal Intraocular Lens
Purpose of this study was to evaluate the effect of presbyopic correction lens on Humphrey visual field (HVF) testing in patients with 2 models of multifocal intraocular lens (MIOL) both with and without glaucoma.
- Trial name
- NCT05220007
- Testing
- Humphrey visual field testing
- Where
- Thailand
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Cataract
Illuminated Chopper in Cataract Surgery
This study compares cataract surgery performed with an illuminated chopper and intracameral illumination with cataract surgery performed under conventional external coaxial microscope illumination.
- Trial name
- IChopper (NCT07840885)
- Testing
- iChopper Illumination Chopper and iVision Light Source, Conventional Microscope Illumination
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- YES Eye Clinic
Myopia
A Clinical Comparison of Two Daily Disposable Contact Lenses.
The objective of this study is to evaluate the clinical performance of two daily disposable contact lenses.
- Trial name
- NCT00775021
- Testing
- etafilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 123 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Comparison of the Capsular Stability With Two Different IOL Models in Patients With Pseudoexfoliation Syndrome: an Exploratory Study
The pseudoexfoliation (PXF syndrome) is caused by production and deposition of extracellular material in the anterior chamber of the eye as well as in other tissues of the body. Approx. 70 million worldwide have a PXF syndrome.
- Trial name
- NCT02155478
- Testing
- ISERT 250 (HOYA, Japan): a standard IOL, AMO ZCB00 IOL (Abbott Medical Optics, United States): a standard IOL
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Astigmatism
The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens
The aim of this study is to evaluate the clinical performance of stenfilcon A toric lenses compared with etafilcon A toric lenses for astigmatism.
- Trial name
- NCT02801006
- Testing
- stenfilcon A, etafilcon A
- Where
- 2 sites in Japan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Intraocular Lens
Visual Outcomes and Contrast Sensitivity in Patients Implanted With Tecnis Eyhance Intraocular Lens
To compare visual outcomes for various distances, reading speed, contrast sensitivity, glare occurence, defocus curve and subjective satisfaction in patients implanted with the extended depth of focus lens (Tecnis Eyhance) in one…
- Trial name
- NCT04800887
- Testing
- TECNIS Eyhance intraocular lens, Monofocal intraocular lens Tecnis ZCB00
- Where
- Czechia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Myopia, Cornea
Euclid Phoenix Lens Design Trial
The "first fit" success rate of the current Euclid orthokeratology "MAX" lens design will be compared to that of the new Euclid orthokeratology MAX "Phoenix" lens design in 30 children.
- Trial name
- NCT06389916
- Testing
- Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design)
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Myopia, Astigmatism
Randomized, Prospective Comparison of the Outcome of Toric Implantable Contact Lens (TICL) and Q-LASIK for the Correction of Myopia With Astigmatism
The objective is to conduct a contralateral prospective clinical study to compare the safety, efficacy, and quality of vision of the STAAR Surgical Co.
- Trial name
- NCT01088568
- Testing
- the implantation of toric implantable collamer lens, customized laser-assisted in situ keratomileusis
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Cataract, IOL
Clinical Analysis of Two Toric Intraocular Lenses
Purpose: Comparison of two torical intraocular lenses with differents haptic design in patients with cataract. Methods: In this prospective, randomized clinical trial 120 eyes of 60 patients underwent phacoemulsification.
- Trial name
- NCT03371576
- Testing
- intraocular lenses
- Volunteers
- 60 people
- Sponsor
- Hospital Hietzing
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.