Clinical trials: Lens Disease
Myopia
Evaluating the Initial Lens Handling Experience of Neophyte Contact Lens Wearers Fitted With Precision1 and 1-Day Acuvue Moist Contact Lenses
The initial subjecting handling experience of neophyte contact lens wearers with Precision1 will be compared to that with a daily disposable lens which mas been on the market for numerous years (1-Day ACUVUE Moist).
- Trial name
- SALUKI (NCT04205162)
- Testing
- Verafilcon A, Etafilcon A
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Product Performance of a New Silicone Hydrogel Contact Lens
The objective of this study is to evaluate the product performance of kalifilcon A, compared to the Johnson \& Johnson Acuvue Oasys® 1-Day with HydraLuxe™ (senofilcon A) daily disposable contact lens and Alcon DAILIES TOTAL1®…
- Trial name
- NCT04901897
- Testing
- kalifilcon A, delefilcon A, senofilcon A
- Where
- 35 sites in United States
- Volunteers
- 805 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Education of Patients
The Effect of Preoperative Education Delivered Using the Pecha Kucha Method on the Quality of Recovery
Objective: The aim of this research is to determine the effect of the Pecha Kucha training method on the quality of patient recovery in patient education.
- Conditions
- Cataract, Education of Patients, Postoperative Recovery
- Trial name
- NCT07383168
- Testing
- Education with Pecha Kucha
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cataract, Cataract Senile
Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement
The introduction of presbyopia-correcting intraocular lenses (PC-IOLs) has provided cataract and refractive surgeons the ability to provide patients with a wider range of visual success and spectacle independence post-cataract…
- Conditions
- Cataract, Cataract Senile, Presbyopia
- Trial name
- NCT04570579
- Testing
- Vivity Extended Depth of Focus Intraocular Lens
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Alanna Nattis, DO
Cataract (Post-operative Cataract Surgery Follow-up), Refraction Error
Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery?
Astigmatism is a common cause of continued dependence on glasses after cataract surgery and may lead to patient dissatisfaction with surgical outcomes.
- Trial name
- AST-2 (NCT07623317)
- Testing
- Adapted clear corneal incisions
- Volunteers
- 100 people
- Sponsor
- Linkoeping University
Demodex Blepharitis
Demodex Blepharitis in Scleral Lens Wearers
The purpose of this study will be to see if Xdemvy (lotilaner ophthalmic solution) 0.25% has a positive impact on ocular surface symptoms and PROSE device functionality and performance.
- Trial name
- NCT07561450
- Testing
- Xdemvy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Boston Sight
Cataract
Study of Phacodepth Required for Safe and Effective Chop During Phacoemulsification for Cataract.
There is a correlation between phacodepth required for full thickness nuclear crack and the various grades of cataract
- Trial name
- CALIBCHOP (NCT01256918)
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Dr. Ram Manohar Lohia Hospital
Cataract
Neural Compensation, Visual Function and Visual Quality After Monofocal or Multifocal Intraocular Lens Implantation
Multifocal intraocular lenses (MIOLs) provide enhanced far and near visual acuity, but they can bring about halos and glare, which are caused by design deficiencies of the IOLs.
- Trial name
- NCT02644720
- Testing
- multifocal intraocular lens implantation, monofocal intraocular lens implantation, Dexamethasone
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Glaucoma, Glaucoma, Open-Angle
Pigment Dispersion Syndrome With and Without Glaucoma
To compare patients having PDS without and with OH or GL by documenting and following the clinical features and course of their disease and evaluating the patient's performance on a variety of diagnostic tests.
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Ocular Hypertension
- Trial name
- NCT00001152
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- National Eye Institute (NEI)
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of MSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "MSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716385
- Testing
- MSiHy Silicone Hydrogel Soft Contact Lens, Monthly Silicone Hydrogel Contact Lenses (oA)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Cataract
Developing an Atlas to Teach Nurses to Clean Micro-instruments Used in Cataract Surgery: Effect on Patient Safety
Aims and objectives The purpose of this study was to develop an atlas to explore the effect of micro-instrument cleaning on the safety of cataract surgery.
- Trial name
- NCT02867189
- Testing
- atlas of micro-instrument
- Volunteers
- 120 people
- Sponsor
- Hua Liu
Cataract
The Visual Plasticity During Adversity and Prosperity in Infants With Congenital Cataracts
Phenotypic plasticity is the ability of individuals to change their phenotypic status when exposed to environmental variations. However, whether the plastic changes show differential susceptibility in adversity and prosperity is…
- Trial name
- NCT03593824
- Testing
- bilateral cataract removal surgery for dense cataract, bilateral cataract removal surgery for non-dense nuclear cataract
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Cataract
Safety and Effectiveness of the Opira AIOL in Comparison to Commercial IOLs in Patients Undergoing Cataract Surgery
This is a clinical trial comparing an investigative accommodative IOL and two commercial IOLs in patients with cataracts undergoing primary cataract surgery.
- Trial name
- NCT04756908
- Testing
- Cataract Surgery
- Where
- 2 sites in Costa Rica, Mexico
- Volunteers
- 200 people
- Sponsor
- FSV6, Ltd.
Cataract
Prospective, Multicenter, Non-comparative Clinical Investigation to Support Safety & Effectiveness of I.SPACE®
I.SPACE® is a hyaluronic acid injectable gel CE (European Conformity) marketed since 2010. It is indicated for use as a surgical aid in ophthalmic anterior segment surgery.
- Trial name
- PROMIR (NCT05146310)
- Testing
- I.SPACE®
- Where
- 3 sites in France
- Volunteers
- 81 people
- Sponsor
- Laboratoires Vivacy
Cataract, Presbyopia
Comparison of Two Aspheric Intraocular Lenses for Micro-monovision
In an aging population, cataract and presbyopia become increasingly common. A cataract develops when the natural crystalline lens inside a person's eye, becomes cloudy over time, causing reduction of vision.
- Conditions
- Cataract, Presbyopia, Pseudophakia
- Trial name
- NCT05531110
- Testing
- Cataract surgery with insertion of Eyhance ICB00, Cataract surgery with insertion of Alcon SN60WF
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Myopia
Efficacy and Safety of the New Defocus Spectacle Lens in Preventing Progression of Myopia
The clinical effects of new technical spectacles with refractive correction function are mixed. A randomised trial is designed to compare the effects of new defocusing spectacle lenses and traditional aspheric spectacle lenses on…
- Trial name
- NCT05740904
- Testing
- New defocus spectacle lenses, Convenional aspheric single-vision spectacle lenses
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
High Myopia, Cataract
The Role of Capsular Tension Rings in Intraocular Lens Stability in High Myopia Cataract Patients: A Prospective Self-Controlled Study
Study Purpose: This prospective, self-controlled clinical study aims to evaluate the impact of capsular tension rings (CTR) on intraocular lens (IOL) stability in high myopia patients undergoing bilateral cataract surgery.
- Trial name
- NCT07052825
- Testing
- CTR implantation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jin Yang
Keratoconus
Comparative Analysis of the Visual Performance After TICL Implantation in Patients With Stable Keratoconus
To report on 4-year postoperative safety, efficacy, stability and predictability outcomes(to evaluate the visual, refractive, contrast sensitivity, defocus curve and aberrometric data preoperation, and compare with a similar…
- Trial name
- TICL (NCT02833649)
- Testing
- Toric Implantable collamer Lens
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Cataract
PureSee/Odyssey Mix-and-Match IOL
Observational, prospective, bilateral, single-arm investigator-initiated study. Single cohort at one site: TECNIS PureSee intraocular lens in the dominant eye and TECNIS Odyssey intraocular lens in the non-dominant eye.
- Trial name
- NCT07898917
- Testing
- Mix-and-match PureSee/Odyssey cohort
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gainesville Eye Associates
Cataract
Capella Scientia Development Study
This study involves collecting biometry and aberration data using the next generation biometer, Unity DX.
- Trial name
- NCT06987474
- Testing
- Unity DX and SMARTCataract DX (SCDX) Biometer, IOLMaster 700 Biometer, Argos with Alcon Image Guidance Biometer
- Where
- 5 sites in United States, India and 2 more
- Volunteers
- 400 people
- Sponsor
- Alcon Research
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