Clinical trials: Lens Disease
Cataract Bilateral, Presbyopia
Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT03771274
- Testing
- Tecnis ZLB00 & Symfony IOL
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Astigmatism
Clinical Performance of Atypical Contact Lens Powers on Subjects With Astigmatism
This study will evaluate the fitting characteristics and physiological response of two toric lenses manufactured by Vistakon.
- Trial name
- NCT00697190
- Testing
- senofilcon A toric, galyfilcon A toric
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Myopic Astigmatism
A Clinical Trial Assessing the Safety and Effectiveness of Orthokeratology Lenses in Patients With Myopia and Myopic Astigmatism
This is a prospective, multi-centre, single-arm clinical trial to evaluate the effectiveness and safety of MCOK-01 lenses in patients with myopia and myopic astigmatism who need dioptric correction.
- Trial name
- SEMOA (NCT07047924)
- Testing
- MCOK-01
- Where
- 4 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Menicon Co., Ltd.
Cataract
Observational, Prospective Clinical Investigation on Mini 4 Ready Intraocular Lens
Cataract surgery presents an extremely high success rate in improving vision and quality of life and it is currently the most commonly performed ophthalmic surgery, especially considering its growing utility in the aging…
- Trial name
- NCT06093880
- Testing
- monofocal intraocular lens
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- SIFI SpA
Corneal Diseases
The Relation Between BSS Solution Temperature and Endothelial Cells and Post Phaco Discomfort
patients underwent phacoemulsification , balanced saline solution used during the operation will be at room temperature in one group and cool 2.7 c in the other group.
- Trial name
- NCT06904560
- Testing
- phacoemulsification
- Volunteers
- 40 people
- Sponsor
- Sohag University
Lid Wiper Epitheliopathy
Lid Wiper Epitheliopathy Trial
The purpose of this study is to evaluate the effect of contact lens lubricity on lid wiper epitheliopathy (LWE) in symptomatic contact lens wearers.
- Trial name
- NCT01870856
- Testing
- Spectacles, Delefilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 187 people
- Sponsor
- Alcon Research
Cystoid Macular Edema
Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
Purpose: Study the effect of nepafenac ophthalmic suspension 0.1% to prevent post-operative cystoid macular edema following uncomplicated cataract surgery Participants: Patients having cataract surgery at UNC who meet eligibility…
- Trial name
- NCT00494494
- Testing
- Standard Care, nepafenac
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
Comparability of Keratometry of VERION Image Guided System With Established Measuring Devices
The purpose of this study is to determine if the keratometric functions of the VERION Image Guided System are comparable to those of established keratometric devices (IOLMaster 500, Pentacam HR, LenStar LS900).
- Trial name
- NCT02377154
- Testing
- Slit lamp, Autorefractor, IOLMaster 500
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Lens Diseases
Study on the Application of Intraoperative Optical Coherence Tomography Technique in the Diagnosis and Treatment of Lens Diseases
Accurately assessing and dealing with anterior segment changes in the eyes of patients with lens diseases can better guide the operation details during surgery and make reasonable plans for possible intraoperative and…
- Trial name
- NCT06687356
- Testing
- Surgery with Intraoperative Optical Coherence Tomography application, Conventional surgery
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract
Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye
The objective is to assess binocular distance-corrected near (40 cm) visual acuity of patients after uneventful cataract surgery with bilateral implantation of the AcrySof® Vivity Intraocular lens (IOL) when the non-dominant eye…
- Trial name
- NCT04482439
- Testing
- Vivity Extended Depth of Focus intraocular lens (IOL)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Newsom Eye & Laser Center
Cataract, Nuclear Progressive
The Post-Vitrectomy Lenstatin™ Study
To determine the efficacy of Lenstatin™, an over-the-counter nutritional supplement, in inhibiting the progression of nuclear cataract in eyes after pars plana vitrectomy.
- Trial name
- NCT02131194
- Testing
- Lenstatin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lenstatin LLC
Myopia
Myopia Control in Children: Comparison of Defocus Incorporated Multiple Segments® Lenses Versus Atropine 0.05% Eyedrops
Myopia is the most common refractive disorder in the world. Many strategies have been developed to control myopia in children. Among them, the instillation of low-concentration atropine eyedrops has been proven to be effective in…
- Trial name
- ATROSMART (NCT05062031)
- Testing
- Defocus Incorporated Multiple Segments® (DIMS®) lenses, Atropine 0.05% eyedrops, Monofocal lenses
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Glaucoma, Cataract
Vivity Outcomes in Patients With Early Stage Glaucoma
The goal of the study is to determine the visual outcomes in patients with mild, pre-perimetric glaucoma who undergo cataract surgery with implantation of the Alcon Vivity Extended Range Intraocular Lens (IOL).
- Conditions
- Glaucoma, Cataract, Presbyopia
- Trial name
- VIVA (NCT04670575)
- Testing
- Cataract Surgery with Implantation of Vivity Extended Range of Vision IOL
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vance Thompson Vision
Cataract, Cataract Mature
Study of the Efficiency and Workflow of Femtosecond Laser Assisted Cataract Surgery in a Spanish Public Hospital
Purpose: To assess the time-efficiency of a designated operation room (OR) workflow in the introduction of Femtosecond laser-assisted cataract surgery (FLACS, LenSx, Alcon®).
- Conditions
- Cataract, Cataract Mature, Cataract, Nuclear
- Trial name
- FLACS (NCT03931629)
- Testing
- CONVENTIONAL PHACO
- Volunteers
- 167 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Astigmatism
Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
The relative performance of a new toric soft contact lens against toric contact lenses currently available in market, specifically for visual acuity and lens orientation.
- Trial name
- NCT00584831
- Testing
- senofilcon A, balafilcon A, omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Corneal Astigmatism
Tomographic Analysis of Anterior, Posterior, Total Corneal Refractive Power Changes After Laser-assisted Keratotomy
To analyze the effect of femtolaser-assisted keratotomy on corneal astigmatism (anterior, posterior and Total corneal refractive power) measured by Scheimpflug tomography after laser lens surgery.
- Trial name
- NCT03097302
- Testing
- Laser keratotomy
- Volunteers
- 23 people
- Sponsor
- University Clinic Frankfurt
Vision Disorders
Effect of Lens Presentation on the Clinical Oculomotor Assessment at Near
This study will compare near clinical oculomotor parameters (heterophoria, vergence ranges, AC/A and accommodative findings) measured when lenses and/or prisms are introduced using three different instruments namely: (i) a…
- Trial name
- NCT02679313
- Testing
- Phoropter
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Cataract
The Use of an Anterior Chamber Maintainer as a Sole Fluid Source in Micro Incision Cataract Surgery as Compared to a Standard Phacoemulsification Procedure
The purpose of this study is to compare the use of an Anterior Chamber Maintainer (ACM) as the sole fluid source in phacoemulsification micro incision cataract surgery (using 1.1mm corneal incision) as opposed to conventional…
- Trial name
- NCT01553760
- Testing
- Phacoemulsification using an ACM as the sole fluid source, Conventional Phaco
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Disorders of the Eye Following Cataract Surgery
Microbiological Evaluation of the Ocular Flora Before Cataract Surgery
The purpose of the present study is to elucidate the spectrum of ocular flora and their antimicrobial susceptibility profiles in patients undergoing routine cataract surgery.
- Trial name
- NCT02124603
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- SIFI SpA
Cataract
Clinical Safety and Efficacy of Hydrophilic Acrylic Intraocular Lenses
Clinical safety and efficacy of CT ASPHINA 409 IOLs after implantation
- Trial name
- UVEA409 (NCT03145103)
- Testing
- CT ASPHINA 409
- Where
- Sweden
- Volunteers
- 282 people
- Sponsor
- Carl Zeiss Meditec AG
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