Clinical trials: Lens Disease
Presbyopia
Vivity IOL: Emmetropia Compared to Monovision.
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT05464732
- Testing
- Vivity IOL emmetropia, Vivity IOL monovision
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Refraction Error, Photorefractive Keratectomy
Comparison of Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses Versus Non-Medicated Bandage Contact Lenses on Postoperative Pain Control After Photorefractive Keratectomy
Photorefractive keratectomy (PRK) is a well-established surface ablation procedure for the correction of refractive errors. Despite excellent visual and refractive outcomes, postoperative pain remains a significant concern…
- Trial name
- NCT07705763
- Testing
- Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses, Contact Bandage Lenses
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Madina Teaching Hospital Faisalabad
Refractive Error, Corneal Implantation
Piggyback Sulcoflex Toric IOL for Correcting Refractive Error Following Corneal Transplantation
A prospective study to evaluate the safety and efficacy of a piggyback sulcoflex toric intraocular lens in pseudophakic patients for correcting refractive errors following corneal transplantation
- Conditions
- Refractive Error, Corneal Implantation, Intraocular Lens Implantation
- Trial name
- NCT01718184
- Testing
- toric intraocular lens implantation, Sulcoflex intraocular lens implantation
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Pseudophakic Cystoid Macular Edema
Efficacy of Nonsteroidal Anti-Inflammatory Drugs for the Prevention of Cystoid Macular Edema Following Cataract Phacoemulsification
This randomized clinical study evaluated the effectiveness of different postoperative nonsteroidal anti-inflammatory drug (NSAID) regimens in patients undergoing uncomplicated phacoemulsification cataract surgery.
- Trial name
- NCT07696104
- Testing
- Bromfenac 0.09 % Ophthalmic Solution, Nepafenac 0.1% eyedrops, diclofenac 0.1% ophthalmic susp.
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Pomeranian Medical University Szczecin
Myopia
Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of three silicone hydrogel contact lenses over a 2 week period.
- Trial name
- NCT01244516
- Testing
- galyfilcon A, BC 8.30, lotrafilcon B, BC 8.60, comfilcon A, BC 8.60
- Where
- 35 sites in United States
- Volunteers
- 540 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Incipient Cataract, Senile Nuclear Sclerosis
Resident-Performed Laser-Assisted vs Manual Traditional Phacoemulsification Cataract Surgery
The study design will be a prospective study comparing laser-assisted cataract extraction cases and traditional manual phacoemulsification cases.
- Trial name
- NCT02561104
- Testing
- Laser-assisted cataract surgery., Traditional manual phacoemulsification
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- University of Texas Southwestern Medical Center
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Refractive Errors, Myopia
Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
The goal of this observational study is to test whether surgeries for lenses designed to be implanted in the eye to correct refractive error can be done without the need for using viscoelastic substances that are used routinely…
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism, Hypermetropia
- Trial name
- NCT06371079
- Testing
- phakic intraocular lens implantation traditional, phakic intraocular lens implantation reduced OVD
- Where
- Iraq
- Volunteers
- 448 people
- Sponsor
- Loay Abdulmutalib Almusawi
Exfoliation Syndrome, Primary Open Angle Glaucoma
Imaging Lens Deposits in Exfoliation Syndrome
The purpose of this study is to use a special eye imaging technique, anterior segment optical coherence tomography (AS-OCT), to image the lens (the curved, transparent part of the eye that helps you to see clearly by directing…
- Conditions
- Exfoliation Syndrome, Primary Open Angle Glaucoma, Cataracts
- Trial name
- NCT02042703
- Testing
- anterior segment OCT
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Duke University
Cataract, Nursing Caries
Effects of Music and Stress Ball Application on Patients During Cataract Surgery
Cataract is one of the leading causes of preventable blindness in the world and in Türkiye. Cataract surgery is one of the most frequently performed and most reliable surgeries for eye diseases.
- Trial name
- NCT06555770
- Testing
- Music intervention, Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cataract, Dry Eye
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study is to evaluate the efficacy on quality of vision and dry eye signs and symptoms in patients undergoing cataract surgery using the ReZoom® multifocal IOL.
- Trial name
- NCT00349583
- Testing
- Topical Cyclosporine, Tears
- Where
- United States
- Sponsor
- Innovative Medical
Erosion; Cornea, Traumatic
Comparison Between Bandage Contact Lens and Pressure Patching for The Erosion Area and Pain Scale in Corneal Erosion Patients
This research aims to compare between bandage contact lens and pressure patching in reducing size of erosion area and pain scale in corneal erosion patients as well as its complications.
- Trial name
- NCT01809483
- Testing
- Bandage contact lens, Pressure patching
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Udayana University
Cataract, Surgery
Pain Expression in the Perioperative Period of Cataract Surgery
Patients having cataract extraction in the second eye under topical anesthesia with monitored anesthesia care often report increased pain and awareness relative to the first surgery in the fellow eye, despite similar operative…
- Conditions
- Cataract, Surgery, Eye Pain
- Trial name
- NCT01824927
- Testing
- First eye (FE), Second eye (SE), Steroids eye drops
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Evidence Based Cataract Study Group
Cataract; Surgery; Phacoemulsification; Biometry; Intraocular Lens Power
Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification
Cataract is a leading cause of blindness in the world. Cataract surgery is one of the most commonly performed ocular procedures.
- Trial name
- NCT05564455
- Testing
- Biometry with Kane formula, Biometry with SRK-T formula
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Cataract
The Effect of Infusion Pressure on the Outcomes of Phacoemulsification Surgery; the ENHANSE Study
The effect of infusion pressure on the outcomes of phacoemulsification surgery.
- Trial name
- ENHANSE (NCT04637685)
- Testing
- Centurion Phacoemulsification System
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Cataract, Macular Degeneration
S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000
RATIONALE: Aging may affect a person's vision. Vitamin E and/or selenium may help prevent cataracts or age-related macular degeneration in men receiving these drugs as part of a clinical trial for the prevention of prostate…
- Trial name
- SEE (NCT00784225)
- Testing
- selenium, vitamin E
- Where
- United States
- Volunteers
- 13,475 people, healthy volunteers welcome
- Sponsor
- SWOG Cancer Research Network
Open-angle Glaucoma
Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract
To evaluate the safety and efficacy of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate open angle glaucoma.
- Trial name
- NCT00721968
- Testing
- Glaucoma Stent Surgery (GTS400 Stent), cataract surgery alone
- Volunteers
- 62 people
- Sponsor
- Glaukos Corporation
Cataract, Astigmatism
Patient Perception of Visual Distortions
The purpose of this study is to evaluate visual distortions reported by pseudophakic patients.
- Trial name
- NCT02203747
- Testing
- Administration of patient self-assessment
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Ocular Inflammation, Crystalline Lens; Chalcosis
A Study of Ear Nerve Stimulation to Treat Eye Inflammation
The purpose of this study to find out whether a device that delivers mild electrical stimulation to the ear (transcutaneous auricular vagus nerve stimulation, or taVNS) can reduce inflammation in the eye in people with ocular…
- Conditions
- Ocular Inflammation, Crystalline Lens; Chalcosis, Intraocular Lens Complication
- Trial name
- NCT07831876
- Testing
- Cymbathera One System
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Aphakia, Astigmatism
Clareon IOL Retrospective Data Collection
The purpose of this study is to provide real world evidence (RWE) on the performance of the Clareon ultraviolet absorbing (UVA) intraocular lenses (IOLs) to support the overall body of evidence on the Clareon IOL family.
- Trial name
- NCT05796674
- Testing
- Clareon UVA IOL, WaveTec Optiwave Refractive Analysis (ORA) System, Cataract surgery
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- Alcon Research
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