Clinical trials: Lens Disease
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Daily Disposable Lens Wearers
The purpose of this study is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of two different daily disposable contact lenses.
- Trial name
- NCT01035905
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens
- Volunteers
- 63 people
- Sponsor
- CIBA VISION
Astigmatism
Clinical Performance of Toric Hydrogel Contact Lenses Following One Week of Daily Wear
The aim of this prospective study is to evaluate the clinical performance of filcon IV1 toric and ocufilcon D toric contact lenses after 1 week of wear in each pair.
- Trial name
- NCT02847169
- Testing
- filcon IV1 toric lens, ocufilcon D toric lens
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of 2 different care systems (one hydrogen peroxide based cleaning and disinfecting system and one PHMB containing multipurpose system) with…
- Trial name
- ID11-56 (NCT01594294)
- Testing
- AOSEPT® Plus contact lens solution, ReNu MultiPlus® contact lens solution, Etafilcon A contact lenses
- Volunteers
- 100 people
- Sponsor
- Alcon Research
Keratoconus
The Homburg Keratoconus Center (HKC)
Aim of this study is to conduct longitudinal and cross-sectional analyses about the corneal ectatic disease Keratoconus based on data obtained from Keratoconus patients in the Homburg Keratoconus Center (HKC).
- Trial name
- NCT03923101
- Testing
- Topographic, tomographic and biomechanical analysis.
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Universität des Saarlandes
Aphakia, Cataract
Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) to reduce postoperative refractive…
- Trial name
- NCT03660865
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- RxSight, Inc.
Refractive Errors, Presbyopia
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
The purpose of this clinical trial is to assess on-eye performance and overall fit of an investigational multifocal toric contact lens to aid in confirmation of the study lens design.
- Conditions
- Refractive Errors, Presbyopia, Astigmatism
- Trial name
- NCT05886907
- Testing
- Lehfilcon A multifocal toric contact lenses, Samfilcon A multifocal toric contact lenses, CLEAR CARE
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
Evaluation of Toric Intraocular Lens(IOL) Combined With Capsular Tension Ring(CTR) in Patients With Cataract Combined With High Myopia
The objective of this study is to evaluate the postoperative visual quality and IOL stability in patients with cataracts and high myopia who have undergone surgery using astigmatism-correcting IOLs in conjunction with tension…
- Conditions
- Cataract, Astigmatism, Intraocular Lens Rotation
- Trial name
- NCT06571773
- Testing
- intraoperative implantation of Capsular Tension Ring, none intraoperative implantation of CTR
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai 10th People's Hospital
Myopia
Performance Evaluation of DAILIES® TOTAL1™ in First Time Contact Lens Wearers
The purpose of this study was to evaluate the performance of DAILIES® TOTAL1™ in first time contact lens wearers.
- Trial name
- NCT01494545
- Testing
- Delefilcon A contact lens
- Volunteers
- 102 people
- Sponsor
- Alcon Research
Cataract
Accuracy of the New Barrett TAL Formula With the Argos Measurements: A Multicenter Prospective Study
This study is a prospective, multi-site, multi-surgeon, observational study of refractive accuracy with the Argos using BTAL after successful cataract surgery.
- Trial name
- NCT06085131
- Testing
- Argos
- Where
- 6 sites in United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- Shammas Eye Medical Center
Astigmatism
Comparison of Senofilcon A Toric Lenses to Balafilcon A Toric Lenses Over Extended Wear Period
To evaluate two toric contact lenses on the ocular physiology of existing contact lens wearers when used in an extended wear modality of days/six nights.
- Trial name
- NCT00762502
- Testing
- senofilcon A toric contact lens, balafilcon A toric contact lens
- Where
- 8 sites in United States, Australia
- Volunteers
- 112 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Manipulating Temporal Expectations to Accelerate Recovery After Cataract Surgery
This study tested whether changing how quickly patients expect to heal after cataract surgery changes how quickly their vision recovers. Adults having cataract surgery in both eyes were randomly assigned to one of two groups.
- Trial name
- NCT07899112
- Testing
- Faster-timeline video and healing-attention surveys, Standard-timeline video and matched surveys
- Where
- 2 sites in United States
- Volunteers
- 147 people
- Sponsor
- Harvard University
Vision Impairment and Blindness, Glaucoma
Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice
In this cohort study, the investigators will test vision screenings in Danish general practice for patients over 70 years of age with minimum one chronic condition.
- Conditions
- Vision Impairment and Blindness, Glaucoma, Age-Related Macular Degeneration, Cataract
- Trial name
- DETECT (NCT07015034)
- Testing
- focus on vision impairment in older patients in general practice
- Where
- 2 sites in Denmark
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dry Eye
Dry Eye OmniLenz Application of Omnigen Research Study
Dry eye disease (DED) is a disease of the ocular surface characterised by ocular surface inflammation and damage and neurosensory abnormalities.
- Trial name
- DOORS (NCT04553432)
- Testing
- Amniotic membrane Omnigen[TM], Bandage soft Contact Lens OmniLenz[R]
- Where
- United Kingdom
- Volunteers
- 79 people
- Sponsor
- Aston University
Myopia
A Comparison of Manufacturing Processes for AIR OPTIX® COLORS Contact Lens
The purpose of this feasibility study was to compare AIR OPTIX® COLORS contact lenses manufactured using an automated process to AIR OPTIX® COLORS contact lenses manufactured using a semi-automatic process.
- Trial name
- NCT01614678
- Testing
- Lotrafilcon B contact lens with color, automated, Lotrafilcon B contact lens with color, semi-automated
- Volunteers
- 49 people
- Sponsor
- CIBA VISION
Presbyopia, Pseudophakia
Identification of Minimum Focal Points in Vision Curve Formation
The primary objective of this study is to identify how many focal points and at which distances are necessary for reliable visual curve formation and area of the curve (AoC) calculation using mathematical models and comparing the…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06260852
- Testing
- Diagnostic Test: Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Cataract
Visual Performance of an Extended Depth of Focus IOL in an Emmetropic or Monovision Modality
Comparison of the visual performance of a refractive extended depth of focus intraocular lens in an emmetropic or monovision modality
- Trial name
- NCT06624826
- Testing
- Emmetropic modality, Monovision modality
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Glaucoma, Diabetic Retinopathy
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits
Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course.
- Conditions
- Glaucoma, Diabetic Retinopathy, Refractive Errors, Cataract
- Trial name
- AL-SIGHT (NCT04328207)
- Testing
- No Financial Incentive, Financial Incentive
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cataracts
Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens
Prospective, multicenter, bilateral, interventional, controlled, masked (sponsor, subjects, and evaluators), randomized clinical trial.
- Trial name
- NCT06377514
- Testing
- Test IOL Model DEN00V, Control IOL Model DCB00
- Where
- 9 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Errors
Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study to evaluate the safety and efficacy of HI-BRITE large diameter rigid gas permeable contact lens (hexafocon b) test when worn on a daily wear basis in the correction of myopia/hyperopia/astigmatism/presbyopia/ and irregular…
- Trial name
- NCT02812316
- Testing
- HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
- Where
- Taiwan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Myopia
Short-term Clinical Performance of Multifocal Soft Contact Lens
The study is aimed to observe the short-term clinical performance of MiSight™ multifocal soft contact lens compared with Proclear™ 1day, including objective examination, subjective acceptability of wearers, and doctors'…
- Trial name
- NCT05273606
- Testing
- MiSight mutifocal soft contact lens, Proclear 1 Day soft contact lens
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
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