Clinical trials: Lens Disease
Cataract
The Cutting Efficiency of Hybrid Tips in Different Grades of Cataract
The objective is to assess the efficiency (as measured by phaco time, aspiration time, and fluid use) of the hybrid tip in removing cataract grade 3 \& 4 in high and low intraocular pressure (IOP) settings.
- Trial name
- NCT05495555
- Testing
- INTREPID® Hybrid tip
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cataract and Laser Institute of Southern Oregon
Cataract, Lens Opacities
Comparison of Clinical Outcomes POD L GF vs POD F GF in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1802 (NCT03688425)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Ametropia
Evaluation of Investigational (Frequent Replacement) FRP Lens for Daily Wear
The purpose of the study is to compare the investigational contact lens to a marketed contact lens. The study results were not used for design validation of investigational contact lens,
- Trial name
- NCT02362724
- Testing
- Sapphire, Pearl
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- CooperVision, Inc.
Fuchs' Endothelial Dystrophy, Cataract
The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
The purpose of this research is to investigate the effects of ripasudil administered as an ophthalmic solution in patients with FED after femtosecond laser assisted cataract surgery.
- Trial name
- NCT06048380
- Testing
- Ripasudil
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore Eye Research Institute
Myopia
Clinical Performance of Existing Wearers of Enfilcon A Following a Refit With Fanfilcon A Lenses for 4 Weeks
The aim of this dispensing study is to evaluate the clinical performance of habitual wearers of enfilcon A lenses following a refit with fanfilcon A lenses over 4 weeks of daily wear.
- Trial name
- NCT02670473
- Testing
- fanfilcon A (test)
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract, Myopia
Measurement of Antioxidant Activity and Oxidative Stress in Patients Undergoing Ophthalmic Surgery.
This trial hypothesized that novel laser refractive surgery techniques (LASIK, KLEx) or laser-assisted cataract surgery (FLACAS) could suppress postoperative inflammation and improve recovery in patients by reducing oxidative…
- Trial name
- NCT06743594
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Cataract
Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery
Using Psychophysics Methods for Quantitative Assessment of Sensory Binocular Imbalance After Cataract Surgery
- Trial name
- NCT06751342
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Cataract, Presbyopia
Evaluation of Long-Term Clinical Acceptability and Satisfaction With the IC-8 Intraocular Lens
The purpose of this study is to evaluate the long-term clinical acceptability and overall satisfaction with the IC-8 IOL at least 12 months post-IOL implantation.
- Trial name
- NCT03314766
- Testing
- IC-8 IOL
- Where
- 7 sites in Germany, Italy and 2 more
- Volunteers
- 64 people
- Sponsor
- AcuFocus, Inc.
Myopia, Preschool
Early Intervention for Premyopic Children
The purpose of this research project is to add evidence of pharmacological (0.01% atropine) and optical (Defocus Integrated Multiple Segments spectacle lenses) approaches for myopia prevention among premyopic preschoolers, which…
- Trial name
- NCT06200194
- Testing
- MiyoSmart Spectacles, 0.01% atropine
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.
Assessing DEXTENZA efficacy when placed within the upper eyelid canaliculus as opposed to the lower eyelid canaliculus.
- Trial name
- NCT04592081
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kerry Assil, MD
Myopia
CHILDREN MYOPIA CONTROL
The purpose of this trial is evaluating the clinical effect of a myopia control spectacle lens compared to a single vision spectacle lens in slowing down the progression of myopia in children living in Israel.
- Trial name
- NCT05477329
- Testing
- Lenses
- Where
- Israel
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Shamir Optical Industry Ltd
Cataracts
A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
The purpose of this study is to compare AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in both eyes (bilateral implantation) to AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in the dominant eye with AcrySof® IQ ReSTOR® +3.0 D Multifocal…
- Trial name
- NCT01684007
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Myopia, Presbyopia
Clinical Comparison of Two Multifocal Contact Lenses Made of Silicone Hydrogel Materials
The purpose of this study was to compare visual performance measures between two multifocal contact lenses on presbyopic wearers.
- Trial name
- NCT01371539
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 109 people
- Sponsor
- CIBA VISION
Cataract, Presbyopia
Clinical Study to Evaluate the LensGen® Juvene® Intraocular Lens
To assess the safety and effectiveness of the Juvene® IOL for the treatment of aphakia and mitigation of the effects of presbyopia after removal of the natural crystalline lens due to cataract.
- Trial name
- Nirvana (NCT05364983)
- Testing
- Juvene IOL, Tecnis® Monofocal (ZCB00, PCB00 or DCB00)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Aphakic Eye
Iris Suture Fixation vs Iris Claw for Correction of Aphakia
Evaluate and compare the advantages and disadvantages of iris suture fixation versus iris claw of posterior chamber IOLs
- Trial name
- IOLs (NCT06933654)
- Testing
- IOL implantation surgery for aphkic eye
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Glaucoma, Cataract
A Comparison of Three Different Formulations of Prednisolone Acetate 1%
Generic prednisolone acetate 1% is less effective than Pred Forte 1% or Econopred Plus 1%.
- Trial name
- NCT00345046
- Testing
- Pred Forte, EconoPred Plus, Prednisolone Acetate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Myopia
Clinical Trial of Several Contact Lenses in Extended Wear
The study is to clinically evaluate currently marketed contact lenses when used in an extended wear modality of up to seven days/six nights.
- Trial name
- NCT00762788
- Testing
- senofilcon A, lotrafilcon A, lotrafilcon B
- Where
- India
- Volunteers
- 350 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Dry Eye Disease (DED), Cataract (Post-operative Cataract Surgery Follow-up)
Effect of Dry Eye Disease on Accuracy of Intraocular Lens Power Calculation Before Phacoemulsification
This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome.
- Trial name
- NCT07525336
- Testing
- dry eye disease optimization
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cataract
Vivinex Impress XY1-EM vs RayOne EMV
Comparison of the outcomes of bilateral implantation of extended depth of vision (EDOF) intraocular lenses (IOLs): the Rayone EMV and the Vivinex Impress XY1-EM in patients with cataract
- Trial name
- NCT06891092
- Testing
- RayOne EMV, Vivinex Impress
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Bialystok
Presbyopia
1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia
Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study.
- Trial name
- NCT05325931
- Testing
- kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
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