Clinical trials: Lens Disease
Cataract
"A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation"
Cataract surgery is the most common surgical procedure performed on humans today. The postoperative regimen includes a combination of steroids, NSAIDs (non-steroidal anti-inflammatory drugs) and antibiotics.
- Trial name
- NCT04781335
- Testing
- Dexycu, Standard of Care post operative eye drops (steroid, antibiotic, NSAID)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Eye Institute of West Florida
Ametropia
Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Testing the Safety and Acceptability of Using a Rewetting Drop with Contact Lenses
- Trial name
- NCT00691197
- Testing
- Carboxymethylcellulose sodium and Glycerin, Carboxymethylcellulose sodium
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Allergan
Ocular Inflammation
Efficacy and Safety Study of IBI-10090 in Cataract Surgery Patients
This study will test the efficacy and safety of IBI-10090 in the treatment of ocular inflammation after cataract surgery.
- Trial name
- NCT01214174
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- ICON Bioscience Inc
Lens Diseases
Association Between Pseudoexfoliation Syndrome and Diabetes Mellitus
Pseudoexfoliation syndrome (PEX) is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye and was first described in 1917 by Lindberg.
- Trial name
- NCT03741153
- Testing
- slit lamp
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cataract
A Novel Congenital Cataract Category System
Congenital cataracts (CC) are the leading cause of childhood visual disabilities and treatable childhood blindness worldwide1. CC patients have a wide range of presentations of lens opacities and are generally categorized into…
- Trial name
- NCT02793869
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Sun Yat-sen University
Cataract
A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects
This investigator-initiated trial is a prospective, randomized, parallel-group, bilateral implantation study comparing Clareon TruPlus versus Clareon monofocal intraocular lenses (IOLs).
- Trial name
- NCT07693205
- Testing
- Clareon TruPlus, Clareon monofocal
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Berkeley Eye Center
Cataract
Comparison Between Low-Dose and High-Dose Nepafenac Sodium
In South Punjab, Pakistan, where tertiary hospitals manage a high cataract workload, data on nepafenac sodium to reduce this inflammatory response is not up to the mark.
- Trial name
- NCT07749027
- Testing
- Nepafenac sodium (High-dose ), Nepafenac sodium (Low-dose )
- Where
- Pakistan
- Volunteers
- 176 people
- Sponsor
- Muhammad Aamir Latif
Cataract Extraction
EyeKon Medical Inc. Capsular Tension Ring Study
This study evaluates the safety and effectiveness of a capsular tension ring (CTR) when used during cataract surgery. Capsular Tension Rings are used during intraocular lens implantation to give added support in order to keep the…
- Trial name
- CTR (NCT02332369)
- Testing
- Capsular Tension Ring
- Where
- 3 sites in United States
- Volunteers
- 125 people
- Sponsor
- EyeKon Medical, Inc.
Cataract
Stability of Secondary Intraocular Lenses With no Capsular Support
Assessment and differences in the centration, tilt and wobble of two secondary IOLs without capsular support.
- Trial name
- NCT06345846
- Testing
- IFIOL, SFIOL
- Where
- Austria
- Volunteers
- 82 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Astigmatism
Clinical Evaluation of Two Toric Soft Contact Lenses
The aim of this study is to compare the short-term clinical performance of two toric contact lenses.
- Trial name
- NCT06490302
- Testing
- Lens A (ocufilcon D), Lens B (fanfilcon A)
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Cataract, Presbyopia Correction
Visual Quality and Performance of Eyes With Asqelio™ EDoF Toric Lenses
This study evaluates the optical quality and clinical performance of the Asqelio™ EDOF Toric intraocular lens (IOL) in patients undergoing cataract surgery or refractive lensectomy.
- Trial name
- NCT06707545
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- AST Products, Inc.
Cataract
Safety and Efficacy of FLACS With the FEMTO LDV Z8 Laser Compared to Conventional Cataract Surgery in Chinese Patients
This trial will be designed as a multi-center randomized non-inferiority clinical trial to demonstrate safety and efficacy of the FEMTO LDV Z8 laser for cataract surgery in a Chinese population in China compared to the…
- Trial name
- Z8CAT01 (NCT03953053)
- Testing
- Femtosecond Laser Assissted Cataract Surgery
- Where
- Switzerland
- Volunteers
- 132 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Cataract
Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients
By comparing DEL-1 and IL-17 levels in the aqueous humor of diabetic cataract patients with the aqueous humor of non-diabetic patients, we aim to understand the biochemical effects of diabetes-related inflammatory processes in…
- Trial name
- DEL-1 and IL-1 (NCT06995131)
- Testing
- Observational Study Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Uşak University
Ocular Hypertension
Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear
The purpose of this study is to determine if short-term wear of a spherical rigid contact lens, called a scleral lens, will raise intraocular pressure in ocular hypertensive patients.
- Trial name
- NCT04442464
- Testing
- Scleral Lens
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Contact Lens Discomfort, Meibomian Gland Dysfunction
Meibomian Gland Dysfunction Management
The purpose of this study is to compare electronic debridement of the eyelid margin (BlephEx) to manual debridement of the eyelid margin as treatment options for patients intolerant to contact lens wear consequent to Meibomian…
- Trial name
- NCT03652337
- Testing
- BlephEx, Manual debridement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of the Incarnate Word
Refractive Errors
Measurement of Refractive SE Following Implantation of LS313 MF30 IOL
This Study determines the most precise method for measuring post-operative refraction following implantation of the asymmetric multifocal LS-313 MF30 comparing the results of Refraction of the different Autorefractor Keratometers…
- Trial name
- NCT03292614
- Testing
- Measurements of the postoperative refraction
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Cataract, Vision
Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs
The purpose of this study is to evaluate and compare the depth of focus and visual outcomes after implantation of the Acrysof IQ SN60WF aspheric intraocular lens (IOL) and the Acrysof Natural SN60AT spherical IOL.
- Trial name
- NCT00886249
- Testing
- Acrysof IQ, Acrysof Natural IOL
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cataract, Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome
An assessment of the surgical performance of DisCoVisc compared to Healon5 during cataract surgery with intraocular lens implantation where miotic/small pupils or intraoperative Floppy Iris Syndrome exists.
- Trial name
- NCT00711347
- Testing
- DisCoVisc, Healon5
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Alcon Research
Cataract, Lens Disease
Magnetic Resonance Imaging to Study the Normal Eye
This study will assess the value of improved magnetic resonance imaging (MRI) techniques to study the lens of the human eye. Knowledge of how cataracts develop and progress has been hampered by the lack of human tissue available…
- Trial name
- NCT00005911
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract
Parameters of 2 Phaco Tips Designs in Torsional Phacoemulsification
To compare the efficiency of surgical procedures using 2 phaco tip designs in torsional phacoemulsification using the bevel-down technique.
- Trial name
- NCT02089698
- Testing
- Mini-flared, Reversed tip
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
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