Clinical trials: Lens Diseases
Refractive Error
Clinical Performance of a Silicone Hydrogel for Daily Disposable Wear
The purpose of this study is to compare the visual acuity of an investigational silicone hydrogel to a commercially available silicone hydrogel in contact lens wearers.
- Trial name
- NCT03095027
- Testing
- FID122819 contact lenses, Stenfilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Cataract
Clinical Safety and Efficacy of Hydrophilic Acrylic Intraocular Lenses
Clinical safety and efficacy of CT ASPHINA 409 IOLs after implantation
- Trial name
- UVEA409 (NCT03145103)
- Testing
- CT ASPHINA 409
- Where
- Sweden
- Volunteers
- 282 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Intraocular Lens (IOL) Calculation Improvement
Intraocular Lens (IOL) formulas sometimes differ from expected. Using novel measurement methods before and after cataract surgery improved formulas are tried be developed.
- Trial name
- NCT01372657
- Testing
- biometry calculation
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University Hospital, Basel, Switzerland
Myopia
CHILDREN MYOPIA CONTROL
The purpose of this trial is evaluating the clinical effect of a myopia control spectacle lens compared to a single vision spectacle lens in slowing down the progression of myopia in children living in Israel.
- Trial name
- NCT05477329
- Testing
- Lenses
- Where
- Israel
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Shamir Optical Industry Ltd
Cataract
The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction
This will be a single arm, open-label, prospective study of patient-reported outcomes of patients with bilateral implantation of the Panoptix or Panoptix Toric implant.
- Trial name
- NCT05346172
- Testing
- PanOptix or PanOptix Toric IOL
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Cataract, Macular Degeneration
Technology-based Eye Care Services (TECS) Compare
The purpose of this study is to compare the Technology-based Eye Care Services (TECS) protocol to the standard face to face ophthalmologic exam.
- Conditions
- Cataract, Macular Degeneration, Glaucoma
- Trial name
- NCT02558712
- Testing
- Technology-based Eye Care Services (TECS) Protocol
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Emory University
Diabetic Macular Edema, Cataract Senile
Influence of Cataract Surgery on Early DME The DICAT-II Study
To determine if cataract surgery may have an impact on the natural history of early DME (E-DME)
- Conditions
- Diabetic Macular Edema, Cataract Senile, Surgery--Complications
- Trial name
- DICAT-II (NCT04096131)
- Testing
- cataract surgery
- Where
- Switzerland
- Volunteers
- 143 people
- Sponsor
- European School of Advanced Studies in Ophthalmology
Cataract
Effect of 1.8-mm Steep-axis Clear Corneal Incision on the Posterior Corneal Astigmatism in Candidates for Toric IOL Implantation
we aimed to analyze the effects of cataract surgery using a 1.8-mm steep-axis clear corneal incision (CCI) on the posterior corneal surfaces based on the keratometry from the rotating Scheimpflug imaging device (Pentacam HR) in…
- Trial name
- NCT04924231
- Testing
- astigmatism
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Age-Related Macular Degeneration, Cataract
Age-Related Eye Disease Study (AREDS) Follow-Up
This study is a 5-year extension of the AREDS protocol, in which investigators followed the natural course of age-related macular degeneration (AMD) and cataracts.
- Trial name
- NCT00594672
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Eye Institute (NEI)
Myopia
Dual Focus Soft Contact Lens Wear Cessation Study
The purpose of this study is to investigate the effect of ceasing treatment with dual focus soft contact lenses.
- Trial name
- NCT05779072
- Testing
- Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Meibomian Gland Dysfunction, Dry Eye
Treatment of Meibomian Gland Dysfunction and Dry Eye in Contact Lens Wearers
The pilot study objective is to evaluate the potential benefits of LipiFlow® System treatment of contact lens wearers with meibomian gland dysfunction and evaporative dry eye by assessing for improvement in meibomian gland…
- Trial name
- NCT02102464
- Testing
- LipiFlow treatment
- Where
- 6 sites in United States, Canada
- Volunteers
- 55 people
- Sponsor
- TearScience, Inc.
Cataract
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
Prospective, randomized, multicenter, multi-arm, subject and vision-assessor-masked, two stage study with Stage 1 as a three-arm initial enrollment period, followed by Stage 2 as a head-to-head study refined based on the Stage 1…
- Trial name
- NCT06922084
- Testing
- Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Cataract
A Single-arm, Open-label Feasibility Study for Assessing the Safety and Performance of the Modified AssiAnchor
The AssiAnchor 2 is a fixation ophthalmic device. The device is manufactured by Hanita Lenses from PMMA material which is being used for the production of Intra-ocular lenses.
- Trial name
- cataracts (NCT03455114)
- Testing
- AssiAnchor
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Hanita Lenses
Refractive Error, Dry Eye
Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers
The purpose of the study is to investigate the corneal epithelial cell response associated with lens wear that results in solution-induced corneal staining (Phase1) and to determine the cell appearance in symptomatic and…
- Trial name
- ABBOTSFORD (NCT01629706)
- Testing
- Balafilcon A contact lens, Habitual contact lenses, Renu multi-purpose solution
- Volunteers
- 92 people
- Sponsor
- CIBA VISION
Myopia
Correction of Myopia Evaluation Trial 2
The purpose of the study is to determine if progressive addition lenses (PALs) versus single vision lenses (SVLs) slow the progression of low myopia in children with poor accommodative responses (i.e., large accommodative lags)…
- Trial name
- COMET2 (NCT00320593)
- Testing
- Progressive Addition Lenses (PALs), Single Vision Lenses (SVLs)
- Where
- 8 sites in United States
- Volunteers
- 118 people
- Sponsor
- Jaeb Center for Health Research
Contact Lens and Punctal Plug in Preventing Corneal Injuries
A Comparison Between Bandage Contact Lens, Punctal Plugs and Standard Measures in Preventing Corneal Injuries
Study Rationale: The insertion of a bandage contact lens or punctal plug in a defined group of patients admitted to the ICU may be more effective than standard care in decreasing the incidence of corneal injuries.
- Trial name
- COMLENPLSTAN (NCT01961193)
- Testing
- contact lens, punctal plug
- Where
- Israel
- Volunteers
- 105 people
- Sponsor
- Rabin Medical Center
Lens Subluxation
A Modified-simple Technique for Managing Moderate and Severe Subluxated Lens Extraction
The investigators describe a modified knotless Z-suture technique to stabilize the capsular bag to the sclera in eyes with moderate and severe ectopic lentis requiring cataract surgery using a standard CTR.
- Trial name
- NCT06627062
- Testing
- moderate and severe subluxated lens extraction
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Astigmatism
Clinical Evaluation of Invigor Toric 1-Day Contact Lenses
An evaluation of the clinical performance of the 1-day toric test contact lens compared to the 1-day toric control contact lens over one hour of lens wear.
- Trial name
- NCT04016623
- Testing
- 1-day toric test contact lens, 1-day toric control contact lens
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Refractive Error
Lubricity Post-Wear - Competitive Lenses Pilot
The purpose of this study is to measure the coefficient of friction of three silicone hydrogel, daily disposable contact lenses after 16 hours of wear.
- Trial name
- NCT02402127
- Testing
- Narafilcon A contact lenses, Stenfilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Cataracts, Glaucoma
Family Studies of Eye Traits
This study will examine blood specimens from patients with various eye disorders who previously participated in the Beaver Dam Eye Study to try to identify genes responsible for these disorders.
- Conditions
- Cataracts, Glaucoma, Myopia
- Trial name
- NCT00342342
- Where
- 5 sites in United States
- Volunteers
- 7,370 people
- Sponsor
- National Human Genome Research Institute (NHGRI)