Clinical trials: Lens Implantation, Intraocular
Cataract
Influence of DisCoVisc Ophthalmic Viscosurgical Device (OVD) on Intraoperative Aberrometry Readings
The purpose of the study is to develop a nomogram that correlates intraoperative, aphakic refraction measurements when the anterior chamber is pressurized with either balanced salt solution (BSS) or DisCoVisc; and to understand…
- Trial name
- NCT03751033
- Testing
- BSS, DiscoVisc
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Clinical Research Consultants, Inc.
Aphakia
Evaluation of Clareon Vivity/Vivity Toric
This study seeks to generate clinical data from subjects previously implanted with the Clareon Vivity/Vivity Toric Intraocular Lenses (IOLs) or Clareon Monofocal/Clareon Toric IOLs.
- Trial name
- NCT05852470
- Testing
- Clareon Vivity/Vivity Toric Extended Vision IOL, Clareon Monofocal/Clareon Toric IOL
- Where
- 7 sites in United States
- Volunteers
- 155 people
- Sponsor
- Alcon Research
Lens Diseases
Evaluating Presbyopia-Correcting IOLs in Complex Cataract Cases With Anterior Segment Abnormalities
The goal of cataract surgery has evolved from simply restoring sight to providing clear and comfortable full-range vision. Traditionally, monofocal IOLs remain the routine choice for special cases with anterior segment…
- Trial name
- NCT07321756
- Testing
- Unilateral Posterior Chamber Implantation of Presbyopia-Correcting IOL, Unilateral Posterior Chamber Implantation of Monofocal IOL
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Myopia, Myopic Astigmatism
Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)
This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian® Implantable Collamer® Lens (ICL) in study participants who have a diagnosis of myopia or myopia with…
- Trial name
- NCT04283149
- Testing
- EVO/EVO+ Visian ICL
- Where
- 14 sites in United States
- Volunteers
- 327 people
- Sponsor
- Staar Surgical Company
Cataract
Postoperative Total Wavefront Pattern Between Two Types of Intraocular Lenses Implanted in Cataract Surgery
With the advancement of cataract eye surgery and wavefront sensors, the previously unquantifiable refractive measurements have been identified and the high order aberrations have shown their effect on high resolution imaging.
- Trial name
- NCT04701255
- Testing
- phacoemulsification with intraocular lens implantation, ocular aberrometer assesment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cataract, Glaucoma
Effect of Yellow-Tinted Intraocular Lens on Standard Automated Perimetry (SAP) and Short-wavelength Automated Perimetry (SWAP) in Patients With and Without Glaucoma
To investigate the effect of yellow-tinted IOLs on the Short Wave-length Automated Perimetry (SWAP) and Standard Automated Perimetry (SAP) in patients with and without glaucoma.
- Trial name
- NCT01305616
- Testing
- Phacoemulsification with yellow-tinted intraocular lens
- Where
- Iran
- Volunteers
- 34 people
- Sponsor
- Rassoul Akram Hospital
Cataract, Lens Opacities
Comparison of Clinical Outcomes POD L GF vs POD F GF in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1802 (NCT03688425)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Primary Angle Closure Glaucoma, Primary Angle Glaucoma Closure Suspect
Effect of Multifocal Intraocular Lens on Contrast Sensitivity in Primary Angle-Closure Patients
This prospective study included patients with primary angle-closure (PAC or primary angle-closure glaucoma (PACG) and visually significant cataract.
- Conditions
- Primary Angle Closure Glaucoma, Primary Angle Glaucoma Closure Suspect, Senile Cataract
- Trial name
- NCT04972435
- Testing
- Contrast sensitivity
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Siriraj Hospital
Aphakia
Clinical Evaluation of the Lenstec Softec HP1 Intraocular Lens
The study is designed as a post market evaluation of the Softec HP1 IOL for continuance of the CE certificate. The primary effectiveness endpoint is to evaluate the safety and performance levels produced by this IOL in patients…
- Trial name
- NCT03900260
- Testing
- Softec HP1 Intraocular Lens
- Where
- 3 sites in United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Aphakia, Postcataract
Trial to Investigate the Safety and Effectiveness of the KI-362-US1 (YP2.2VM) Intraocular Lens (IOL) in Adult Participants for Correction of Aphakia Following Cataract Extraction
A study to learn how well an artificial lens, called an intraocular lens (IOL), works in adults who have cataract surgery. During this type of surgery, the eye's natural lens is removed and replaced with an artificial lens to…
- Trial name
- NCT07650201
- Testing
- KI-362-US1 (YP2.2VM)
- Volunteers
- 340 people
- Sponsor
- Kowa Research Institute, Inc.
Cataract
Postoperative Rotational Dynamics of Three Toric Intraocular Lens Designs
This prospective comparative cohort study evaluates and compares postoperative rotational stability and time-course dynamics of three commercially available toric intraocular lenses (TECNIS Toric II [ZCU], AcrySof IQ Toric, and…
- Trial name
- 3 TORIC ROTATE (NCT07453992)
- Testing
- TECNIS Toric II (ZCU), AcrySof IQ Toric, AT TORBI 709M
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Cataract
Rotational Stability of Acrysof IQ Vivity Extended Vision Toric IOL and Refractive Visual Outcome.
The purpose of this research is to assess the rotational stability of the AcrySof IQ Vivity Extended Vision Toric IOL and Refractive Visual outcome.
- Trial name
- NCT05119127
- Testing
- Alcon Vivity toric intra ocular lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kevin Barber
Cataract, Lens Opacities
Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery
Controlled, open label, prospective Post Market Clinical Follow-Up, single-center clinical study to investigate visual performance after implantation of a trifocal IOL (PhysIOL Pod L GF) in patients that underwent refractive…
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT04054427
- Testing
- IOL implantation experimental
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Presbyopia
Visual and Economic Profits of ReSTOR® Multifocal Intraocular Lenses (IOL) on Public Health Patients in Spain
Surgical correction of presbyopia is possible via the implantation of multifocal intraocular lenses after removal of the crystalline lens.
- Trial name
- NCT01088282
- Testing
- Cataract surgery
- Where
- 2 sites in Spain
- Volunteers
- 120 people
- Sponsor
- University of Barcelona
Cataract
Light Filters in Intraocular Lenses (IOLs) and Its Influence on Colour and Contrast Vision.
Visible-light-filtering IOLs are implanted increasingly often in cataract surgery. Several studies examined the effect of light-filters on contrast and colour vision. However, the study outcomes were varying.
- Trial name
- NCT00612729
- Testing
- Polylens Y30 intraocular lens, Orange Series Model PC 440 Y intraocular lens
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Hospital Hietzing
Cataract, Presbyopia
Clinical Study to Evaluate the LensGen® Juvene® Intraocular Lens
To assess the safety and effectiveness of the Juvene® IOL for the treatment of aphakia and mitigation of the effects of presbyopia after removal of the natural crystalline lens due to cataract.
- Trial name
- Nirvana (NCT05364983)
- Testing
- Juvene IOL, Tecnis® Monofocal (ZCB00, PCB00 or DCB00)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Cataract, Pseudophakia
Safety and Efficacy of the Hydrophobic Intraocular Lens Asqelio Monofocal With Biaspheric Design
The goal of this observational study is to learn about the Asqelio monofocal intraocular lens (IOL) model QLIO130C in patients undergoing cataract surgery.
- Trial name
- NCT06056154
- Testing
- LIO ASQELIO TM monofocal QLIO130C
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- AST Products, Inc.
Cataract
Clinical Investigation of the Modified Rayner Monofocal Aspheric 600C (With Axis Marks) Intraocular Lens
This will be a prospective, open-label, 125 subject (maximum), two-year multicentre investigation to assess the safety, effectiveness and rotational stability of the modified 600C (axis marks) intraocular lens (IOL) in subjects…
- Trial name
- NCT02378636
- Testing
- 600S
- Where
- United Kingdom
- Sponsor
- Rayner Intraocular Lenses Limited
Aphakia
Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL) With an Improved Injector System
The purpose of this study is to evaluate the clinical outcomes of an investigational IOL in patients undergoing cataract extraction and intraocular lens implantation using an improved injector system.
- Trial name
- NCT02418871
- Testing
- FluidVision AIOL, Cataract surgery
- Where
- 5 sites in Hungary, South Africa
- Volunteers
- 53 people
- Sponsor
- PowerVision
Cataract
Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
This study is a single center, ambispective study of visual outcomes after successful bilateral cataract surgery. Subjects will be assessed at least 3 months postoperatively at a single visit.
- Trial name
- NCT06550375
- Testing
- TECNIS Odyssey IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mann Eye Institute