Clinical trials: Lens Implantation, Intraocular
Glistenings
Evaluation of Glistenings in Intraocular Lenses Implanted in Normal Patients Following Routine Cataract Extraction.
Evaluation of glistenings in intraocular lenses implanted in normal patients following routine cataract surgery. The lenses used will be Model X-60 made by the AVS company Vs AcrySof MA50BM made by the Alcon company.
- Trial name
- AVS Vs MA50BM (NCT01131481)
- Testing
- Intraocular lens
- Where
- United States
- Sponsor
- Fry Eye Associates and Fry Eye Surgery Center
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Cataract
Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
This study will involve up to 20 bilateral patients per surgeon. Patients will be assessed pre-operatively, and at subsequent visits (following the implantation of the intraocular lens in the second eye) at 1 week, 1 month, 3…
- Trial name
- NCT00934622
- Testing
- AcrySof® ReSTOR® Aspheric IOL
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Congenital Cataract, Intraocular Lens Implantation
Comparison of the Efficacy of Intraocular Lens Optic Capture and In-the-bag Implantation Over 1 Year in Children With Congenital Cataract
Approximately 30 eyes with congenital cataract who underwent primary or secondary intraocular lens implantation surgery at Zhejiang Eye Hospital from March 2018 to December 2020 were enrolled.
- Conditions
- Congenital Cataract, Intraocular Lens Implantation, Optic Capture
- Trial name
- NCT05275764
- Testing
- primary or secondary intraocular lens implantation surgery
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Wenzhou Medical University
Aphakia, Cataract
RxSight Light Adjustable Lens and Light Delivery Device New Enrollment Study
The primary objective of this study is to conduct a post-approval study which compares the LAL to a monofocal control IOL for safety outcomes.
- Trial name
- NCT05202808
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 14 sites in United States
- Volunteers
- 500 people
- Sponsor
- RxSight, Inc.
Cataract, Corneal Endothelial Keratopathy
Staged and Combined Surgery for Cataract Patients With Corneal Endothelial Dysfunction
The purpose of this study is to evaluate the safety and efficacy of staged and combined phacoemulsification with intraocular lens implantation and Descemet membrane endothelial keratoplasty (DMEK) to treat cataract patients with…
- Conditions
- Cataract, Corneal Endothelial Keratopathy, Phacoemulfisication+IOL Implantation, Endothelial Keratopathy
- Trial name
- NCT02523950
- Testing
- Staged phacoemulsification and DMEK, Combined phacoemulsification and DMEK, Intraocular lens (IOL) implantation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Haotian Lin
Patients Implanted With Monofocal Intraocular Lens
Prospective Evaluation of Near and Intermediate Visual Outcomes With Monofocal Intraocular Lenses: The Mast Study
The purpose of this study is to evaluate the near and intermediate visual outcomes of patients who have undergone routine cataract surgery (removal of cloudy crystalline lens) with phacoemulsification (the break-up and removal of…
- Trial name
- NCT01191515
- Testing
- Monofocal Intraocular Lenses
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataract
Evaluation of the Rotational Stability
To evaluate rotational stability of the investigational device implanted after cataract surgery.
- Trial name
- NCT03247751
- Testing
- intraocular lens
- Volunteers
- 95 people
- Sponsor
- Nidek Co. LTD.
Cataract
I-ZIP Ocular Bandage Pivotal Study
To evaluate the safety and performance of the I-ZIP Ocular Bandage in subjects undergoing uneventful unilateral clear corneal phacoemulsification with foldable monofocal intraocular lens (IOL) implantation compared with the Oasis…
- Trial name
- NCT00774228
- Testing
- I-ZIP Ocular Bandage, Oasis 24 Hour Soft Shield Collagen Corneal Shield
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Ocular Therapeutix, Inc.
Cataract
Binocular Vision in Monocular Pseudophakia
Following cataract surgery, an intraocular lens (IOL) is implanted in the eye. The majority of people develop an operable cataract when they are over the age of 50.
- Trial name
- BVMP (NCT01872000)
- Testing
- Cataract surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Intraocular Lens
Rotation of an Intraocular Lens - HOYA Vivinex iSert P261
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. In the UK, more than half of people who are over 65 years old have some cataract development in one or both eyes.
- Trial name
- Rot P261 (NCT03157375)
- Testing
- Intraocular Lens Implantation
- Where
- Austria
- Volunteers
- 66 people
- Sponsor
- Medical University of Vienna
Congenital Cataract
Infant Aphakia Treatment Study (IATS)
The primary purpose is to determine whether infants with a unilateral congenital cataract are more likely to develop better vision following cataract extraction surgery if they undergo primary implantation of an intraocular lens…
- Trial name
- IATS (NCT00212134)
- Testing
- Contact lens correction of aphakia, Intraocular lens implantation
- Where
- 13 sites in United States
- Volunteers
- 114 people
- Sponsor
- Stanford University
Intraocular Lens, Cataract
Comparison of a Novel Non-diffractive Extended Depth of Focus Intraocular Lens (IOL) and a Trifocal IOL
The purpose of this study is to compare visual performance and quality of life (QOL) following bilateral implantation of a novel non-diffractive extended depth-of-focus (EDOF) intraocular lens (IOL) (AcrySof® IQ Vivity, Alcon…
- Conditions
- Intraocular Lens, Cataract, Quality of Life
- Trial name
- NCT05262504
- Testing
- İntraocular lens implantation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Baskent University Ankara Hospital
GLAUCOMA 1, OPEN ANGLE, D (Disorder), Cataract
Comparison of Visual Outcomes and Patient Satisfaction in Mild to Moderate Glaucoma Patients Undergoing Cataract Surgery With EDOF Versus Monofocal IOLs
Cataract is the leading cause of reversible vision loss, while glaucoma remains the primary cause of irreversible blindness, often impairing contrast sensitivity (CS), glare tolerance, and dark adaptation.
- Trial name
- NCT07436871
- Testing
- Cataract surgery (Monofocal intraocular lens implantation), cataract surgery (Extended depht of focus intraocular lens implantation)
- Volunteers
- 74 people
- Sponsor
- OMIQ Research
Cataract
A Dynamic Study of Pupil Diameter After Artificial Lens Implantation in Patients With High Myopia
Age-related cataract remains the leading cause of blindness in developing countries. And, with the aging of the population in these countries, the number of cataract patients will continue to grow.
- Trial name
- NCT06505434
- Testing
- Cataract surgery
- Volunteers
- 60 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Cataract
Vivinex Impress XY1-EM vs RayOne EMV
Comparison of the outcomes of bilateral implantation of extended depth of vision (EDOF) intraocular lenses (IOLs): the Rayone EMV and the Vivinex Impress XY1-EM in patients with cataract
- Trial name
- NCT06891092
- Testing
- RayOne EMV, Vivinex Impress
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Bialystok
Astigmatism
Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)
The purpose of this study is to generate clinical data to quantify the impact of residual astigmatism on the overall visual performance during distance, intermediate, and near viewing in patients implanted with Clareon Vivity…
- Trial name
- NCT06784063
- Testing
- Clareon Vivity Extended Vision IOL
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Cataract
Clinical Investigation of Omega Refractive Capsule, Model VI
The objective of this study is to evaluate the safety and effectiveness of the investigational Omega Refractive Capsule (model VI)
- Trial name
- ORCVI (NCT04574115)
- Testing
- Omega Refractive Capsule with an FDA approved Intraocular Lens, FDA approved Intraocular Lens
- Where
- Costa Rica
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Aphakia, Cataract
Single Center Exploratory Study To Evaluate The Use Of The RxSight Light Adjustable Lens (LAL) And The Light Delivery Device (LDD) To Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT04529616
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 79 people
- Sponsor
- RxSight, Inc.
Cataract
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
Prospective, randomized, multicenter, multi-arm, subject and vision-assessor-masked, two stage study with Stage 1 as a three-arm initial enrollment period, followed by Stage 2 as a head-to-head study refined based on the Stage 1…
- Trial name
- NCT06922084
- Testing
- Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center