Clinical trials: Lenses, Intraocular
Cataract
Evaluation of the Rotational Stability
To evaluate rotational stability of the investigational device implanted after cataract surgery.
- Trial name
- NCT03247751
- Testing
- intraocular lens
- Volunteers
- 95 people
- Sponsor
- Nidek Co. LTD.
Aphakia, Presbyopia
Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population
The primary objective of this clinical study is to assess the clinical performance of the PanOptix IOL in a Chinese population.
- Trial name
- NCT04755231
- Testing
- AcrySof IQ PanOptix Presbyopia Correcting IOL, Cataract surgery
- Where
- 9 sites in China
- Volunteers
- 181 people
- Sponsor
- Alcon Research
Cataract
To Compare Early Rotation of Two Extended Depth of Focus Intraocular Lenses
To demonstrate that the Carl Zeiss Meditec (CZM) Extended depth of focus (EDOF) Intraocular lens (IOL) is superior to the competitor EDOF IOL with respect to Rotational Stability.
- Trial name
- VENUStoric (NCT03839420)
- Testing
- CZM IOL, Competitor IOL
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Carl Zeiss Meditec AG
Aphakia, Cataract
Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.
This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.
- Conditions
- Aphakia, Cataract, Clear Lens Exchange, Refractive Lens Exchange
- Trial name
- NCT05290870
- Testing
- Posterior-chamber intraocular lens
- Where
- Netherlands
- Volunteers
- 2,183 people
- Sponsor
- Teleon Surgical B.V.
Inflammation, Pain
Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation
The purpose of this study is to evaluate the clinical efficacy and safety of XG-102 (900µg) compared to vehicle in the treatment of subjects with inflammation and pain following cataract surgery.
- Conditions
- Inflammation, Pain, Cataract
- Trial name
- NCT02235272
- Testing
- XG-102
- Where
- United States
- Volunteers
- 339 people
- Sponsor
- Xigen SA
Cataract
Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery System (EGDS) compared to placebo in patients…
- Trial name
- NCT01602068
- Testing
- Dexamethasone Phosphate Ophthalmic, 100 mM Sodium Citrate Buffer
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Aphakia
A Real-World Evidence (RWE) Long-Term Follow-Up Study to Assess Outcomes of Alcon Monofocal Intraocular Lenses
The purpose of this post-market clinical follow-up (PMCF) study is to describe the long-term safety and performance of AcrySof Single-Piece and AcrySof Multi-Piece monofocal intraocular lenses (IOLs).
- Trial name
- NCT05799950
- Testing
- AcrySof single-piece IOL, AcrySof multi-piece IOL
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 138 people
- Sponsor
- Alcon Research
Presbyopia, Ametropia
Clinical Trial With Artiflex Presbyopic (Artiplus)
The purpose of this clinical trial is to evaluate the effectiveness and safety of the multifocal Artiflex Presbyopic (Artiplus) intraocular lens.
- Conditions
- Presbyopia, Ametropia, Refractive Errors, Myopia
- Trial name
- NCT04632784
- Testing
- Artiflex Presbyopic (Artiplus) implantation
- Where
- 7 sites in South Korea, Spain
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ophtec BV
Cataract
Evaluation of 3 Intraocular Lenses Following Lens Extraction
The objective of this study is to evaluate the efficacy and subject satisfaction with three different FDA approved lenses for adults over 40 years of age who desire a reduction in spectacle dependence.
- Trial name
- NCT01122576
- Testing
- Crystalens AO, ReSTOR, Tecnis Multifocal IOL
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Presbyopia
Evaluation of Long-Term Clinical Acceptability and Satisfaction With the IC-8 Intraocular Lens
The purpose of this study is to evaluate the long-term clinical acceptability and overall satisfaction with the IC-8 IOL at least 12 months post-IOL implantation.
- Trial name
- NCT03314766
- Testing
- IC-8 IOL
- Where
- 7 sites in Germany, Italy and 2 more
- Volunteers
- 64 people
- Sponsor
- AcuFocus, Inc.
Cataract, Aphakia
Visual and Refractive Outcomes of The ClarVista HARMONI™ Modular Intraocular Lens System (HMIOL)
The purpose of this study was to evaluate visual and refractive outcomes with the use of the HARMONI™ Modular Intraocular Lens (HMIOL) System implantation, assembly, and optic exchange in subjects undergoing cataract surgery.
- Trial name
- NCT03681886
- Testing
- Harmoni Modular Intraocular Lens, Optic Exchange
- Volunteers
- 150 people
- Sponsor
- ClarVista Medical
Cataract
Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.
- Trial name
- NCT01061918
- Testing
- Tecnis MF, ReSTOR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Glaucoma, Ocular Hypertension
Evaluation of the Safety, Efficacy, Dose Response of the Bimatoprost Drug Ring System (BIM-DRS) in Pseudophakic Patients Diagnosed With Open Angle Glaucoma or Ocular Hypertension
The goal of this clinical trial is to learn if two different doses of the SpyGlass Bimatoprost-Drug Ring System (BIM-DRS) work to treat adult pseudophakic patients with either glaucoma or ocular hypertension.
- Trial name
- NCT07641296
- Testing
- BIM-DRS Low Dose, BIM-DRS High Dose, SpyGlass IOL with silicone pads (no drug)
- Volunteers
- 24 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataracts
Contralateral ReSTOR / Monofocal or Phakic Eye
Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.
- Trial name
- NCT00731640
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Presbyopia
Visual Outcomes After Presbyopic Lens Exchange
Evaluation of mean preoperative and postoperative Corrected distance visual acuity (CDVA) after Refractive Lens Exchange in presbyopic patients
- Trial name
- RELAX (NCT03790592)
- Testing
- trifocal IOL
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Carl Zeiss Meditec AG
Visual Acuity
Comparative Study of Photopic and Mesopic Distance, Intermediate and Near Visual Acuity, and Spectacle Independence
The purpose of this study is to evaluate visual acuity in different lighting conditions (daylight and night time) and distances (distance, near and intermediate), and the independence of glasses, in patients who have had…
- Trial name
- NCT01191502
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Cataract
Clinical Evaluation of a New Aspheric Intraocular Lens.
This study evaluates the visual performance and occurrence of posterior capsular opacification after implantation of a new aspherical intraocular lens compared with a control spherical lens of otherwise identical design.
- Trial name
- NCT00786565
- Testing
- Advanced Akreos Adapt in one operated eye., Akreos Adapt in fellow operated eye.
- Volunteers
- 75 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Evaluation of the BunnyLens TR Intraocular Lens
With age, a human crystalline lens opacifies (cataract) disabling the eye in generating a clear, well contrasted image. The only therapeutic solution to this problem is surgical replacement of the crystalline lens with an…
- Trial name
- NCT01659801
- Testing
- BunnyLens TR
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Tilt and Decentration
Comparison of Methods for Assessing Intraocular Lens Position
Prospective, multi-center, non-interventional, open label, clinical study.
- Trial name
- NCT07218419
- Testing
- IOL Decentration Assessment
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.