Clinical trials: Lenses
Myopia, Refractive Errors
DD T2 Daily Disposable Registration Trial
The purpose of this study is to evaluate the performance of the investigational verofilcon A contact lens compared to the commercially available delefilcon A contact lens, by assessing visual acuity as the primary variable.
- Trial name
- NCT03305770
- Testing
- verofilcon A contact lenses, delefilcon A contact lenses
- Where
- 6 sites in United States
- Volunteers
- 107 people
- Sponsor
- Alcon Research
Dry Eye
Safety and Efficacy of Optive in Contact Lens Wearers With Dry Eyes
The purpose of this study is to determine if Optive®eye drops are safe for people who wear contact lenses and have dry eyes. The second goal of the study is to determine if using Optive®eye drops can improve my dry eye scores on…
- Trial name
- NCT00469573
- Testing
- 1. Optive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Contact Lens Solutions
A Range of Contact Lenses and Care System Combinations
The objective of this study is to compare the short-term clinical response to all combinations of two lens types: fanfilcon A and comfilcon A with two care systems: Hy-Care and Lite.
- Trial name
- NCT03632083
- Testing
- Hy-Care Contact Lens Solution, Lite Contact Lens Solution, fanfilcon A soft contact lens
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Cataract
Bioequivalence of Eye Drops and Spray Administration of Vigamox
The study compares the amounts of Vigamox absorbed when administered as eye drops or in a spray form. Both administrations will be prior to patients undergoing elective cataract surgery and the aqueous samples will be analyzed by…
- Trial name
- NCT00666042
- Testing
- Vigamox - administration in spray form, Vigamox eye drops
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Advanced Ophthalmic Pharma
Cataract
Comparison of Femto-laser and Manually Created Clear Corneal Incisions During Cataract Surgery
The aim of this study is to test the hypothesis, that in terms of Surgically Induced corneal Astigmatism (SIA), Higher-order Aberrations (HOA), and wound geometry the femtosecond clear corneal incisions (CCIs) created during…
- Trial name
- Z8_CCI (NCT04082273)
- Testing
- Femtosecond Laser for Cataract Surgery, Conventional Cataract Surgery
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Astigmatism
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
This is a prospective, multi-center, subject-masked, bilateral, daily wear, two-month dispensing study
- Trial name
- NCT02921412
- Testing
- fanfilcon A
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract
EYEFILL® C. -US Viscoelastic Clinical Investigation
The purpose of this multicenter, prospective, randomized clinical study is to determine the safety and effectiveness of the EYEFILL® C.-US Viscoelastic in patients undergoing cataract extraction and intraocular lens (IOL)…
- Trial name
- NCT02024711
- Testing
- EYEFILL® C.-US Viscoelastic, Healon® Viscoelastic (CONTROL)
- Where
- 8 sites in United States
- Volunteers
- 262 people
- Sponsor
- Bausch Health Americas, Inc.
Cataracts
A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
The purpose of this study is to compare AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in both eyes (bilateral implantation) to AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in the dominant eye with AcrySof® IQ ReSTOR® +3.0 D Multifocal…
- Trial name
- NCT01684007
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Refractive Error - Myopia Simple
Evaluation of the Safety and Efficacy of PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3)
The goal of this clinical trial is to learn if PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3) are safe and effective for vision correction in adults.
- Trial name
- NCT06995781
- Testing
- Experimental Intervention, Active Comparator Intervention
- Volunteers
- 69 people
- Sponsor
- Pegavision Corporation
Myopia
Two Daily Disposable Contact Lenses in Symptomatic Patients
The purpose of this study is to evaluate the performance of DAILIES TOTAL1® and ACUVUE OASYS® 1-DAY and with respect to visual acuity in a symptomatic study population of monthly or bi-weekly replacement lens wearers.
- Trial name
- NCT03628599
- Testing
- Delefilcon A contact lenses, Senofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 39 people
- Sponsor
- Alcon Research
Myopia
Evaluation of Etafilcon A Daily Disposable Lenses
To evaluate the clinical performance of daily disposable etafilcon A lenses.
- Trial name
- NCT02061592
- Testing
- etafilcon A
- Where
- 7 sites in United States
- Volunteers
- 136 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Multifocal Toric Contact Lenses
This is a double-masked, bilateral, randomized, non-dispensing clinical trial. The study lenses will be worn in a bilateral and random fashion using a 5x5 crossover Williams design with 5 lens types and 5 periods.
- Trial name
- NCT03208088
- Testing
- etafilcon A Investigational Toric Multifocal Contact Lens
- Where
- 7 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Evaluation of Deposits on Contact Lenses Worn Daily Wear
The purpose of this study was to measure front surface deposits on contact lenses when worn for ten hours.
- Trial name
- NCT00725153
- Testing
- Balafilcon A contact lenses (PureVision), Etafilcon A contact lenses (Acuvue2)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Myopia
Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of TOTAL30 contact lenses with Biofinity contact lenses over 30 days of daily wear.
- Trial name
- NCT04980456
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 257 people
- Sponsor
- Alcon Research
Ametropia, Myopia
Apioc Contact Lens Feasibility
This clinical trial will document the feasibility of the Apioc lens design by assessing which lens shape parameters yield successful on-eye-fit and movement of the Apioc contact lens design and evaluate the subjectively-reported…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03688672
- Testing
- Apioc Contact Lens Design
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Cataract
Clinical Results of Asqelio™ EDOF Toric Soft Hydrophobic Intraocular Lens After Cataract Surgery
The goal of this observational study is to assess the clinical outcomes of binocular implantation of Asqelio EDOF Toric IOLs in healthy cataract patients.
- Trial name
- NCT06229756
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AST Products, Inc.
Astigmatism
Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study was to compare the clinical performance of two monthly toric silicone hydrogel contact lenses in habitual wearers, when worn for 1-month each.
- Trial name
- NCT05933772
- Testing
- Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
- Where
- 5 sites in United States, Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
This is a multi-center, randomized, double-masked clinical trial. All study devices are market approved/cleared in the localities where the study is conducted.
- Trial name
- PROTECT (NCT05159765)
- Testing
- Single vision contact lenses, Multifocal contact lenses
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Cataract, Astigmatism
Toric Intraocular Lens Following Cataract Surgery
The objective of this clinical trial is to evaluate the safety and effectiveness of the Bausch + Lomb Toric Accommodating Posterior Chamber Silicone Intraocular Lens used to provide near, intermediate, and distance vision and a…
- Trial name
- NCT01140477
- Testing
- Toric Accommodating Lens, Accommodating Lens
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Bausch & Lomb Incorporated
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