Clinical trials: Lenses
Refractive Errors, Astigmatism
Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens
The purpose of this clinical study is to assess the clinical performance of an investigational toric soft contact lens compared to a commercially available toric contact lens in a crossover dispense trial when worn in a daily…
- Trial name
- NCT05211739
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Cataract, Aphakic Eye
Comparative Study of the Tomey OA-2000, Tomey CASIA2, and the LenStar LS900
This is a prospective comparative study that will be conducted at one clinical site in the United States, in which subjects who sign an informed consent form and fulfil all inclusion and exclusion criteria, will have OCT scans…
- Conditions
- Cataract, Aphakic Eye, Pseudophakia
- Trial name
- NCT06065072
- Testing
- Optical measurement
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Cataract
DisCoVisc Versus DuoVisc, Healon5 and AmVisc Plus
A comparison of the ability of DisCoVisc to that of other ophthalmic viscosurgical devices (OVDs) (DuoVisc, Healon5 or Amvisc PLUS) regarding endothelial protection and anterior chamber space maintenance during non-eventful…
- Trial name
- NCT00712244
- Testing
- DisCoVisc, DuoVisc, Healon5
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Presbyopia
Comparison of a Multifocal Contact Lens to a Traditional Multifocal Contact Lens
The purpose of the trial is to compare the performance of two multifocal contact lens systems/products in established presbyopic subjects.
- Trial name
- NCT00886119
- Testing
- Lotrafilcon B multifocal contact lens, Omafilcon A multifocal contact lens
- Volunteers
- 48 people
- Sponsor
- CIBA VISION
Cataract
Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% for the Treatment of Inflammation and Pain Associated With Cataract Surgery (CLOSE-2)
Cataract surgery is one of the most common surgical procedures performed worldwide. In fact, in 2017, 3.8 million cataracts procedures were performed in the US.
- Trial name
- CLOSE-2 (NCT04249076)
- Testing
- Clobetasol Propionate, Vehicle
- Where
- 18 sites in United States
- Volunteers
- 215 people
- Sponsor
- Salvat
Refractive Error
Lubricity Post-Wear - Competitive Lenses Pilot
The purpose of this study is to measure the coefficient of friction of three silicone hydrogel, daily disposable contact lenses after 16 hours of wear.
- Trial name
- NCT02402127
- Testing
- Narafilcon A contact lenses, Stenfilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Presbyopia
Refitting Multifocal Contact Lens Wearers With a Different Multifocal Contact Lens
The purpose of this study was to compare ease of handling and vision acuity of two multifocal contact lenses to correct presbyopia that are currently CE marked and on the UK market.
- Trial name
- NCT06328660
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- CooperVision International Limited (CVIL)
Cataract
AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR IOLs Six months post cataract surgery.
- Trial name
- NCT01278420
- Testing
- Tecnis MF, ReSTOR
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Myopia, Hyperopia
DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study
The purpose of this study is to continuously assess the visual performance and safety of DAILIES TOTAL1 soft contact lenses in a real world setting and broader patient base through routine clinical practices.
- Conditions
- Myopia, Hyperopia, Presbyopia, Astigmatism
- Trial name
- NCT06483113
- Testing
- Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 192 people
- Sponsor
- Alcon Research
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression (CSL)
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05724186
- Testing
- Test myopia control lenses (CSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Cataract
EDoF IOLs vs Monofocal IOL
prospective, comparative (3 arms), randomized, multicentric clinical trial
- Trial name
- NCT03172351
- Testing
- EDoF1, Monofocal, EDoF2
- Where
- Germany
- Volunteers
- 216 people
- Sponsor
- Carl Zeiss Meditec AG
Myopia
Clinical Comparison of Two Soft Contact Lenses
This study was designed to gather short-term clinical performance data for 2 soft contact lenses.
- Trial name
- NCT06251154
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- CooperVision, Inc.
Cataract Surgery
A Study to Compare Ocular Safety and Tolerability of Eye Drops Containing Prednisolone Acetate in Patients With Intraocular Inflammation After Cataract Surgery
The primary objective was to demonstrate that two days of treatment with 0.5% prednisolone acetate eye-drops after cataract surgery are superior to vehicle in reducing the flare in the anterior chamber of the operated eye.
- Trial name
- NCT00170729
- Testing
- Prednisolone acetate
- Volunteers
- 62 people
- Sponsor
- Novartis
Presbyopia
Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses
This is a study to evaluate the clinical performance and subjective acceptance of an investigational contact lens (test), compared to a marketed lens (control) in an in-office setting.
- Trial name
- NCT03417557
- Testing
- Comfilcon A lens (test), Omafilcon B lens (control)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CooperVision, Inc.
Refractive Error, Myopia
A Comparison of Two Daily Disposable Contact Lenses
This study seeks to evaluate the clinical performance of a new CE marked daily disposable contact lens that contains a wetting agent to a recently improved daily disposable contact lens.
- Trial name
- NCT00634101
- Testing
- nelfilcon A, narafilcon A
- Where
- 20 sites in United Kingdom
- Volunteers
- 129 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Refractive Errors
Safety and Effectiveness of the Qualis Contact Lens
Three-month, open-label, bilateral, parallel group, randomized, daily wear contact lens dispensing study.
- Trial name
- NCT04295499
- Testing
- soft (hydrophilic) contact lens
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Unicon Optical Co. Ltd.
Cataract
Next Generation Cataract Surgery Study
The purpose of this study is to obtain device-specific safety and performance clinical data to support marketability in Europe and to collect user preference data.
- Trial name
- NCT06071104
- Testing
- Anterior segment ophthalmic surgery, UNITY VCS
- Where
- 4 sites in United States
- Volunteers
- 121 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
The Effect of Masking on Subjective Results During Daily Disposable Contact Lens Studies
The purpose of this study is to explore the effect of masking on subjective ratings for two daily disposable contact lenses.
- Trial name
- ARGON (NCT01155726)
- Testing
- Nelfilcon A contact lens, Nelfilcon A contact lens with comfort additive (DACP), unmasked, Nelfilcon A contact lens with comfort additive (DACP), masked
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- CIBA VISION
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